{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:55:52Z","timestamp":1761540952597},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":10967,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1981,1]]},"abstract":"<jats:p><jats:bold>Abstract. <\/jats:bold> Seven new cases of pregnancy combined with von Willebrand's disease have been reported. Altogether the patients had 11 deliveries, and one abortion after 10 weeks' gestation. The diagnosis was based on the determination of the bleeding time, factor VIII coagulant activity (VIII C), factor VIII\u2010related antigen (VIII RAg) and the ristocetin co\u2010factor (VIII RCoF). Two of our 6 parturients showed profuse bleeding at delivery; in addition one patient showed bleeding after abortion at 10 weeks' gestation. Vaginal delivery is generally safe in patiens with von Willebrand's disease. There is a great risk of copious bleeding especially in connection with early abortion, when factor VIII levels are low.<\/jats:p>","DOI":"10.3109\/00016348109155470","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T18:02:15Z","timestamp":1260295335000},"page":"507-509","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["VON WILLEBRAND'S DISEASE AND PREGNANCY"],"prefix":"10.1111","volume":"60","author":[{"given":"R.","family":"Punnonen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Nyman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gr\u00f6nroos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Wall\u00e9n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-44-2-241"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000239850"},{"key":"e_1_2_1_4_1","first-page":"541","article-title":"A propos d'une h\u00e9morrhagie de la d\u00e9livrance due \u00e0 une maladie de Willebrand","volume":"16","author":"Henrion R.","year":"1964","journal-title":"Bull Fed Gyn Obstet Franc"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1968.tb00143.x"},{"key":"e_1_2_1_6_1","first-page":"2236","article-title":"von Willebrand's disease. A critical evaluation of diagnostic criteria","volume":"65","author":"Horowitz H.","year":"1965","journal-title":"New York J Med"},{"key":"e_1_2_1_7_1","first-page":"242","article-title":"Blood clotting factors in pregnancy: factor VIII concentrations in normal and AHF\u2010deficient women","volume":"24","author":"Kasper C. 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