{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T01:21:32Z","timestamp":1698542492745},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":9141,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1986,1]]},"abstract":"<jats:p>In order to evaluate renal tubular function, \u03b2<jats:sub>2<\/jats:sub>\u2010microglobulin was measured in serum and urine from 15 patients with severe pre\u2010eclampsia and 13 normal pregnant women. in the pre\u2010eclamptic group, the serum \u03b2<jats:sub>2<\/jats:sub>\u2010microglo\u2010bulin level was significantly higher (p &lt;0.05) and urinary excretion\/2411 significantly lower (p&lt;0.05), than in the normal pregnant group. A positive linear correlation between serum uric acid and \u03b2<jats:sub>2<\/jats:sub>\u2010microglobulin was observed both in the pre\u2010eclamptic group (r = 0.79, p&lt;0.001) and in the normal pregnant group &lt;r = 0.58, p&lt;0.05). This may indicate that production and renal handling of these two substances are interdependent. Tubular function is reduced in normal pregnancy, whereas increased \u201cnet tubular reabsorption\u201d of uric acid and \u03b2<jats:sub>2<\/jats:sub>\u2010microglobulin occurs in pre\u2010eclampsia. the cause of the observed changes in tubular function is still obscure.<\/jats:p>","DOI":"10.3109\/00016348609158362","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T17:56:20Z","timestamp":1260294980000},"page":"103-106","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Serum Uric Acid Correlates with \u03b2<sub>2<\/sub>\u2010Microglobulin in Pre\u2010Eclampsia"],"prefix":"10.1111","volume":"65","author":[{"given":"P\u00e5l","family":"\u00d8ian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans\u2010Peter","family":"Monrad\u2010Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Martin","family":"Maltau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"856","article-title":"Blood chemistry in pre\u2010eclampsia and eclampsia","volume":"28","author":"Stander H J.","year":"1934","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196012000-00002"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)93024-5"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016348409156277"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-009-8697-8_47"},{"issue":"154","key":"e_1_2_1_7_1","first-page":"27","article-title":"\u03b22\u2010microglobuIin in clinical medicine","volume":"40","author":"Karlsson F A.","year":"1980","journal-title":"Scand J Clin Lab Invest"},{"key":"e_1_2_1_8_1","first-page":"161","volume-title":"Radioimmunoassay and related procedures in medicine","author":"Paus E.","year":"1982"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000396023"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)37509-3"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1977.tb12459.x"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016347409156888"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000180203"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365517209081057"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365518109090529"},{"key":"e_1_2_1_16_1","first-page":"304","volume-title":"Clinical Physiology in Obstetrics","author":"Hytten F.","year":"1980"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(68)90107-1"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107462"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(78)90816-5"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016348609158362","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016348609158362","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T21:12:38Z","timestamp":1697836358000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016348609158362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,1]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1986,1]]}},"alternative-id":["10.3109\/00016348609158362"],"URL":"https:\/\/doi.org\/10.3109\/00016348609158362","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,1]]},"assertion":[{"value":"2011-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}