{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T13:18:14Z","timestamp":1725542294054},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":8776,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:p>The effect of luteinizing hormone releasing hormone (LHRH) on progesterone and estradiol production was studied in human luteal tissue. Tissue slices were incubated in Ham's F\u201010 medium under an atmosphere of 95% O<jats:sub>2<\/jats:sub>; 5% CO<jats:sub>2<\/jats:sub> at 37 \u00b0C for 4 h. Slices were treated with or without human chorionic gonadotropin (HCG) in the presence or absence of LHRH. HCG stimulated progesterone and estradiol production by human luteal tissue in a time\u2010and dose\u2010related manner. LHRH stimulated the basal progesterone production in five (one early luteal and four mid\u2010luteal) of 17 corpora lutea, and stimulated the basal estradiol production in three (all mid\u2010luteal) of 16 corpora lutea. On the other hand, LHRH inhibited HCG\u2013stimulated progesterone production in four (two early heal and two mid\u2013luteal) of 22 corpora lutea. and inhibited HCG\u2010stimulated estradiol production in four (one early luteal and three mid\u2010luteal) of 18 corpora lutea. In the acute short\u2010term incubations of human luteal tissue, therefore, LHRH had little effect on basal and HCG\u2010stimulated steroidogenesis. However, in a few corpora lutea taken in the early or mid\u2010luteal phase, LHRH 5timulated basal steroidogenesis and inhibited HCG\u2010stimulated steroidogenesis.<\/jats:p>","DOI":"10.3109\/00016348709004145","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:05:35Z","timestamp":1194980735000},"page":"695-699","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Effect of Luteinizing Hormone Releasing Hormone (Lhrh) on Steroidogenesis by the Human Luteal Tissue"],"prefix":"10.1111","volume":"66","author":[{"given":"Hisao","family":"Ikoma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mareo","family":"Yamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryosuke","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-2-4-437"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(80)90494-4"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/282090a0"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)46105-4"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0670411"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1010163"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0015-0282(16)47955-0","article-title":"Studies on the effect of gonadotropin\u2010releasing hormone and its agonist on human luteal steroidogenesis in vitro","volume":"42","author":"Casper R F.","year":"1984","journal-title":"Fertil Steril"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-54-5-1078"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-128X(71)90082-1"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-38-1-42"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-55-1-102"},{"key":"e_1_2_1_13_1","first-page":"110146","article-title":"Stimulation of progesterone and prostaglandin E accumulation by luteinizing hormone\u2010releasing hormone (LHRH) and LHRH analogs in rat granulosa cells","author":"Clark M R.","year":"1982","journal-title":"Endocrinology"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-107-2-407"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-107-3-656"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/299056a0"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(83)90844-6"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-61-5-834"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016348709004145","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016348709004145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T10:20:29Z","timestamp":1697797229000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016348709004145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1987,1]]}},"alternative-id":["10.3109\/00016348709004145"],"URL":"https:\/\/doi.org\/10.3109\/00016348709004145","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,1]]},"assertion":[{"value":"2011-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}