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Subjective discomfort, clinical examination of the breast lesions, echomam\u2010mography and breast thermography were evaluated before, during and after 3 months of treatment and in a further follow\u2010up. Plasma levels of estradiol, progesterone and prolactin were measured over the same time. Significant reduction of mastodynia and significant improvement of the breast lesions were observed in the group given bromocriptine, though echomammography and breast thermography did not reveal any significant differences between the two groups. Plasma prolactin levels were significantly reduced by bromocriptine administration.<\/jats:p>","DOI":"10.3109\/00016348709015721","type":"journal-article","created":{"date-parts":[[2007,11,22]],"date-time":"2007-11-22T00:44:37Z","timestamp":1195692277000},"page":"483-488","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Bromocriptine for Treatment of Benign Breast Disease: A double\u2010blind clinical trial versus placebo"],"prefix":"10.1111","volume":"66","author":[{"given":"E.","family":"Parlati","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Polinari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Salvi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Giorlandino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Liberale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Fiorella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Dell'acqua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12678099"},{"key":"e_1_2_1_3_1","first-page":"17P","article-title":"Prolactin receptors in human breast cancer","volume":"73","author":"Morgan L.","year":"1977","journal-title":"J Endocrinol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1400301"},{"key":"e_1_2_1_5_1","first-page":"4115","article-title":"Mastopathies benignes: etude hormonale chez 125 malades","volume":"6","author":"Mauvais\u2010Jarvis P.","year":"1977","journal-title":"Nouv Presse Med"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2964(77)90122-0"},{"key":"e_1_2_1_7_1","first-page":"73","article-title":"La prolactine, son dosage radioim\u2010munologique dans le cancer du sein et les mastopathies benignes de la femme","volume":"3","author":"Gorins A.","year":"1974","journal-title":"Nouv Presse Med"},{"key":"e_1_2_1_8_1","first-page":"4650","article-title":"Disordered nocturnal prolactin regulation in women with breast cancer","volume":"37","author":"Malarkey W B.","year":"1977","journal-title":"Cancer Res"},{"key":"e_1_2_1_9_1","first-page":"101","article-title":"Circadian variations of serum prolactin and TSH of women in health or with mammary carcinoma, fibroadenoma or fibrocystic mastopathy","volume":"7","author":"Tarquini B.","year":"1980","journal-title":"Int J Chronobiol"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/003693308002500449"},{"key":"e_1_2_1_11_1","first-page":"703","article-title":"Treatment of fibrocystic disease of the breast with a prolactin inhibitor: 2\u2010Br\u2010alpha\u2010Ergocryptine (CB\u2010154)","volume":"48","author":"Martin\u2010Comin J.","year":"1976","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03349282"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00673151"},{"key":"e_1_2_1_14_1","first-page":"567","article-title":"Radioimmunoassay of oestrone and oestradiol in human plasma","volume":"69","author":"Emment Y.","year":"1972","journal-title":"Acta Endocrinol"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4731(72)90018-0"},{"issue":"5","key":"e_1_2_1_16_1","first-page":"48","article-title":"Aspects of fibrocystic disease of the breast. 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