{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T06:44:45Z","timestamp":1697957085552},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":8776,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:p>Fourteen consecutive patients (mean gestational age 18.1 weeks, range 15\u201023 weeks) referred for therapeutic termination of pregnancy were induced into abortion by intra\u2010amniotic PGF<jats:sub>2\u03b1<\/jats:sub> 40 mg followed by oxytocin stimulation. 14 other patients (mean gestational age 17.9 weeks, range 15\u201023 weeks) were pretreated with intracervical PGE<jats:sub>2<\/jats:sub> 1.0 mg in gel for 4 h prior to induction of abortion with intra\u2010amniotic PGF<jats:sub>2\u03b1<\/jats:sub> 40 mg without further stimulation. The induction\u2010abortion interval for patients treated with intra\u2010amniotic PGF<jats:sub>2\u03b1<\/jats:sub> and oxytocin, was 19.1 \u00b1 2.94 h (\u00b1SE, n=14) with a success rate of 80% after 24 h. After pretreatment with intracervical PGE<jats:sub>2\u03b1<\/jats:sub> 1.0 mg in viscous gel, intra\u2010amniotic PGF<jats:sub>2\u03b1<\/jats:sub> 40 mg induced abortion after 11.2 \u00b1 1.12 h (\u00b1 SE, n = 14) with a 100% success rate after 24 h. No systemic side effects of the PGE<jats:sub>2<\/jats:sub> pretreatment were noted. No cervical laceration was observed. The results need further confirmation, but still suggest cervical priming with intracervical PGE<jats:sub>2<\/jats:sub> 1.0 mg in gel and subsequent induction of abortion by intra\u2010amniotic PGF<jats:sub>2\u03b1<\/jats:sub> 40 mg as an attractive principle for 2nd trimester abortion.<\/jats:p>","DOI":"10.3109\/00016348709022064","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:05:31Z","timestamp":1194980731000},"page":"603-605","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Combined Intracervical PGE<sub>2<\/sub> and Intra\u2010Amniotic PGF<sub>2\u03b1<\/sub> for Induction of 2nd Trimester Abortion"],"prefix":"10.1111","volume":"66","author":[{"given":"Jim","family":"Allen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svend","family":"Maigaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Forman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Ulmsten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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