{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T17:24:38Z","timestamp":1698773078829},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":8776,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:p>Zinc deficiency was reported to lead to congenital malformations and abnormal fetal development, and zinc concentration in amniotic fluid has been found to be correlated with fetal birth weight. In the present study, zinc concentrations were estimated in 8 pregnant women at 15 gestational weeks and 68 pregnant women at term. Maternal serum zinc concentration in early and term pregnancy was significant!; lower than that of the non\u2010pregnant controls (mean value \u00b1SEM being 9.8\u00b10.6, 9.3\u00b10.2, and 11.5\u00b10.3 \u03bcmol\/l respectively). Maternal serum zinc concentrations reached the non\u2010pregnant level by one week <jats:italic>postpartum.<\/jats:italic> The mean serum zinc concentration in cord blood was 14.4 (\u00b10.4) \u03bcmol\/1. The zinc concentration in the amniotic fluid was very low both ii early pregnancy and at term 1.1 and 0.8 \u03bcmol\/1, respectively and no correlation was found to the birth weight. Low serum zinc content in pregnant women occurs as a normal feature and congenital malformation as a consequence of disturbed zinc metabolism is probably only to be seen in instances of extreme zinc deficiency in conjunction with malnutrition.<\/jats:p>","DOI":"10.3109\/00016348709022074","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:05:27Z","timestamp":1194980727000},"page":"653-656","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Zinc concentrations in maternal blood during pregnancy and post partum, in cord blood and amniotic fluid"],"prefix":"10.1111","volume":"66","author":[{"given":"Karel","family":"Mar\u0161\u00e1l","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Furgyik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(61)90137-1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)91772-3"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)91601-3"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-123-31578"},{"key":"e_1_2_1_6_1","first-page":"344","article-title":"Clinical and biochemical manifestation of zinc deficiency in human subjects","volume":"16","author":"Prasad A S.","year":"1985","journal-title":"J Pharmacol"},{"issue":"593","key":"e_1_2_1_7_1","article-title":"Effects of zinc deficiency in human reproduction","author":"Jameson S.","year":"1976","journal-title":"Acta Med Scand"},{"key":"e_1_2_1_8_1","first-page":"707","article-title":"Les ions metalliques dans le liquide amnioti\u2010que au cours du troisi\u00e8me trimestre de la gestation","volume":"67","author":"Favier M.","year":"1972","journal-title":"Rev Fr Gynecol Obstet"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000241337"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.282.6270.1098"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1093\/ajcn\/41.5.1032","article-title":"Zinc and copper nutrition in human pregnancy: a longitudinal study in normal primigravidae and in primigravidae at risk of delivering a growth retarded baby","volume":"41","author":"Tuttle S.","year":"1985","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00667673"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1042\/cs0440091"},{"key":"e_1_2_1_14_1","first-page":"892","article-title":"Plasmaeisen, Serumkupfer und Serum\u2010zink unter Therapie mit Ovulationshemmern","volume":"69","author":"Heinemann G.","year":"1974","journal-title":"Med Klin"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0002-9378(16)34354-X","article-title":"Zinc and copper levels in pregnant women and those taking oral contraceptives","volume":"103","author":"O'Leary J A.","year":"1969","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_16_1","first-page":"604","article-title":"\u00d6strogen\u2010 und Pregnandiolausscheidung im Wochenbett","volume":"18","author":"Napp J\u2010H","year":"1958","journal-title":"Geburtsh Frauenheilkd"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1037216"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016348709022074","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016348709022074","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T00:31:40Z","timestamp":1697934700000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016348709022074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1987,1]]}},"alternative-id":["10.3109\/00016348709022074"],"URL":"https:\/\/doi.org\/10.3109\/00016348709022074","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,1]]},"assertion":[{"value":"2011-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}