{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:25:19Z","timestamp":1777616719006,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":8776,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:p>In a prospective study of 129 women undergoing induced first\u2010trimester abortion, 14 (10.9%) contracted postabortal pelvic inflammatory disease (PID). Samples of vaginal secretion for quantitation of secretory immunoglo\u2010bulin A (slgA) as well as isolates from cervix\/urethra for the culture of anaerobes and aerobes, including <jats:italic>Bacteroides fragilis et melaninogenicus<\/jats:italic> and <jats:italic>Gardnerella vaginalis<\/jats:italic>, were obtained at the preoperative visit. Two blood samples from each woman with postabortal PID were analysed for antibodies against <jats:italic>G. vaginalis<\/jats:italic>. Twenty\u2010five per cent of women with a history of PID developed postabortal PID, and 25% with vaginitis contracted postabortal infection (p&lt; 0.001 and p&lt;0.005).<\/jats:p><jats:p>Twenty\u2010five per cent of women harboring <jats:italic>C. trachomatis<\/jats:italic> at the time of abortion developed infection. The presence of anaerobes or <jats:italic>G. vaginalis<\/jats:italic> was not associated with the frequency of postabortal PID (all p\u2010values &gt;0.1). One woman with postabortal PID produced a culture positive for <jats:italic>G. vaginalis<\/jats:italic> and a rise in specific antibody titer. The levels of vaginal sIgA were not significantly associated with a positive history of PID (p &gt;0.6), with postabortal PID (p &gt;0.4) or with the presence of anaerobes or <jats:italic>G. vaginalis<\/jats:italic> at the time of abortion (p&gt;0.3). However, significantly elevated levels of slgA were found in women harboring <jats:italic>C. trachomatis<\/jats:italic> (p &lt;0.05). Thus, the study could not demonstrate any correlation between vaginal slgA and PID, but increased sIgA in Chlamydia\u2010positive women. A history of PID and vaginitis entailed a significant risk of contracting postabortal PID.<\/jats:p>","DOI":"10.3109\/00016348709083027","type":"journal-article","created":{"date-parts":[[2007,11,22]],"date-time":"2007-11-22T00:44:14Z","timestamp":1195692254000},"page":"99-102","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The Role of Vaginal Secretory Immunoglobulin a, <i>Gardnerella Vaginalis<\/i>, Anaerobes, and <i>Chlamydia Trachomatis<\/i> in Post Abort al Pelvic Inflammatory Disease"],"prefix":"10.1111","volume":"66","author":[{"given":"Lars","family":"Heisterberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Poul Erik","family":"Branebjerg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie","family":"Bremmelgaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Scheibel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lene","family":"H\u00f8j","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197209072871008"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/S0022-5347(17)57347-4","article-title":"The role of vaginal immunoglobulin A in girls with recurrent urinary tract infections","volume":"120","author":"Tuttle J P.","year":"1978","journal-title":"J Urol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(76)90512-3"},{"key":"e_1_2_1_5_1","first-page":"182","article-title":"Therapeutic abortion and Chlamydia trachomatis infection","volume":"58","author":"Qvigstad E.","year":"1982","journal-title":"Br J Vener Dis"},{"key":"e_1_2_1_6_1","first-page":"322","article-title":"Significance of cervical Chlamydia trachomatis infection in postabor\u2010tal pelvic inflammatory disease","volume":"60","author":"Westergaard L.","year":"1982","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_7_1","first-page":"210","article-title":"Pelvic infection after elective abortion associated with Chlamydia trachomatis","volume":"59","author":"Meller B R.","year":"1982","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-198504000-00004"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(81)90488-9"},{"key":"e_1_2_1_10_1","first-page":"129","article-title":"Secretion rates of immunoglobulins, albumin, haptoglobin, and complement C3 and C4 in the perfused jejunum and ileum of human Salmonella carriers","volume":"92","author":"Lene H\u00f8j","year":"1984","journal-title":"Acta Pathol Microbiol Immunol Scand Sect C"},{"key":"e_1_2_1_11_1","first-page":"879","article-title":"Chlamydia trachomatis ved gonoroisk og non\u2010gonoroisk uretrit","volume":"142","author":"Scheibel J H.","year":"1980","journal-title":"Ugeskr L\u00e6g"},{"key":"e_1_2_1_12_1","volume-title":"Bakteriologiske unders\u00f8gelsesmetoder","author":"Lautrop H.","year":"1979"},{"key":"e_1_2_1_13_1","first-page":"371","article-title":"Metronidazole prophylaxis in elective first trimester abortion","volume":"65","author":"Heisterberg L.","year":"1985","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(84)90670-7"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1984.tb05904.x"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016347809156522"},{"key":"e_1_2_1_17_1","volume-title":"The Ljubljana abortion study. National Institutes of Health","author":"Andolsek L.","year":"1974"},{"issue":"26","key":"e_1_2_1_18_1","first-page":"101","article-title":"Investigation of the prophylactic effect of ti\u2010nidazole on the postoperative infection rate of patients undergoing vacuum aspiration","author":"Krohn K.","year":"1981","journal-title":"Scand J Infect Dis"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016348709083027","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016348709083027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T22:06:22Z","timestamp":1697925982000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016348709083027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1987,1]]}},"alternative-id":["10.3109\/00016348709083027"],"URL":"https:\/\/doi.org\/10.3109\/00016348709083027","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,1]]},"assertion":[{"value":"2011-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}