{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T19:58:46Z","timestamp":1773518326522,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":8411,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1988,1]]},"abstract":"<jats:p><jats:bold>Abstract. <\/jats:bold> The purpose of this paper is to describe the clinical characteristics of HPV\u2010vulvo\u2010vaginitis. Clinical symptoms were recorded in 74 women with the diagnosis of papilloma\u2010virus vulvovaginitis. The diagnosis was established by colposcopic examination, immunological detection of viral structural antigen, and selected biopsies. Patient data were obtained from medical records and by interviews. Discharge, itching, burning, fissures and dyspareunia were typical symptoms. Discharge was more frequent in women with vaginal localization of the HPV infection, whereas itching and burning were the predominant complaint when the HPV lesions were present on the vulva. However, 14 women were asymptomatic. Thirty\u2010nine women had atypical Pap smears. In half of these women, there was no evidence of intra\u2010epithelial neoplasia. In 15 women with atypical Pap smears there was no clinical affection of the cervix uteri. But manifestations of wart virus infection in the vagina and\/or vulva. Papillomavirus vulvovaginitis may be a subclinical infection, but many women suffer from distinct symptoms related to the location of the specific lesions. This infection of the vulva and vagina may be the sole cause of atypical Pap smears. The clinical recognition of this condition is a necessary prerequisite for a rational therapeutic approach.<\/jats:p>","DOI":"10.3109\/00016348809004188","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:05:50Z","timestamp":1194980750000},"page":"147-151","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Clinical Characteristics Of Papillomavirus\u2010Vulvovaginitis: A New Entity With Oncogenic Potential"],"prefix":"10.1111","volume":"67","author":[{"given":"Elisabeth","family":"Bod\u00e9n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Eriksson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Rylander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"von","given":"Bo","family":"Schoultz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"1045","article-title":"Genital warts, human papillomaviruses, and cervical cancer","author":"Editorial","year":"1985","journal-title":"Lancet"},{"key":"e_1_2_1_3_1","first-page":"773","article-title":"The vulvar vestibule","volume":"28","author":"Friedrich E.","year":"1983","journal-title":"J Reprod Med"},{"key":"e_1_2_1_4_1","first-page":"564","article-title":"Pruritic vulvar squamous papillomatosis: Evidence for human papillomavirus etiology","volume":"66","author":"Growdon W A.","year":"1985","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)91273-9"},{"key":"e_1_2_1_6_1","first-page":"379","article-title":"Condylomatous lesions of the cervix 11. 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