{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T23:23:19Z","timestamp":1776468199439,"version":"3.51.2"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":8411,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1988,1]]},"abstract":"<jats:p><jats:bold>Abstract. <\/jats:bold> A very serious case of anaphylactoid reaction to bupivacaine occurred during epidural analgesia. A rise in complement 3 activation products and a decrease in immunoglobulin E were observed, while bupivacaine toxicity was ruled out by normal serum concentration. Severe maternal hypotension, and a sudden decrease in the fetal heart rate were detected clinically. By a cesarean section, a baby girl was delivered, who at the age of 1 year appears normal.<\/jats:p>","DOI":"10.3109\/00016348809004196","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:05:59Z","timestamp":1194980759000},"page":"181-184","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Allergic Reaction to an Amide Local Anesthetic in Segmental Epidural ANALGESIA"],"prefix":"10.1111","volume":"67","author":[{"given":"Risto","family":"Erkkola","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jussi","family":"Kanto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juhani","family":"M\u00e4enp\u00e4\u00e4","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pentti","family":"Kero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marja","family":"Hovi\u2010Viander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markku","family":"Viander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"499","article-title":"Quantitative estimation of proteins by electrophoresis in antibody containing agarose gel","volume":"14","author":"Laurell C B.","year":"1966","journal-title":"Protid Biol Fluids Proc Colloq"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000233101"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.4049\/jimmunol.124.6.2780","article-title":"Activation of the fourth component of complement (C4): assessment by rocket immunoelectrophoresis and correlation with metabolism of C4","volume":"124","author":"Milgrom H.","year":"1980","journal-title":"J Immunol"},{"key":"e_1_2_1_5_1","first-page":"4172","article-title":"Segmental epidural analgesia. A modern method for safe and effective management of labor pains","author":"Kanto J.","year":"1984","journal-title":"Biol Res Pregn"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.293.6544.403"},{"key":"e_1_2_1_7_1","first-page":"837","article-title":"Problems associated with epidural anesthesia in obstetrics","volume":"65","author":"Corke B C.","year":"1985","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_8_1","first-page":"23","article-title":"Obstetric analgesia: pharmacokinetics and its relation to neonatal behavioral and adaptive functions","volume":"5","author":"Kanto J.","year":"1984","journal-title":"Biol Res Pregn"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198303000-00010"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1983.tb13935.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1177\/0310057X7900700110","article-title":"Intradermal testing in the diagnosis of acute anaphylaxis during anaesthesia\u2013results of five year experience","volume":"7","author":"Fisher M M.","year":"1979","journal-title":"Anaesth Intens Care"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(79)90211-2"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(75)90094-9"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/53.4.435"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-198412000-00006"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016348809004196","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016348809004196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T09:03:25Z","timestamp":1697965405000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016348809004196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,1]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1988,1]]}},"alternative-id":["10.3109\/00016348809004196"],"URL":"https:\/\/doi.org\/10.3109\/00016348809004196","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,1]]},"assertion":[{"value":"2011-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}