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Eight chromosomal abnormalities (29.7%) were detected, including 45, X (2 cases), trisomy 21(1 case), 46, XY, \u221213,+t(13, 13) (1 case), 47, XX, +18 (3 cases), 47, XXY (1 case). Nineteen fetuses had a normal karyotype (46, XX: 9 cases, 46, XY: 10 cases). The fetal karyotype was available within 72 h and fetal management was planned accordingly. We concluded that in fetuses with an abnormal sonogram, rapid karyotyping using fetal blood obtained under ultrasound guidance had important implications in obstetric and neonatal management and would facilitate genetic counselling.<\/jats:p>","DOI":"10.3109\/00016348809004275","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:06:30Z","timestamp":1194980790000},"page":"621-625","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rapid Karyotyping in Fetuses with Abnormal Sonogram"],"prefix":"10.1111","volume":"67","author":[{"given":"Fon\u2010Jou","family":"Hsieh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han\u2010Chuan","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsang\u2010Ming","family":"Ko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fong\u2010Ming","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsi\u2010Yao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Her\u2010Heng","family":"Jean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So\u2010Ming","family":"Chuang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1542\/peds.43.1.79","article-title":"Congenital atresia and stenosis of the duodenum","volume":"43","author":"Fonkalsrud E W.","year":"1969","journal-title":"Pediatrics"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198310063091403"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90528-7"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(81)90028-4"},{"key":"e_1_2_1_6_1","first-page":"153","article-title":"Role of amniocentesis in ultrasound\u2010detected fetal malformations","volume":"68","author":"Platt L D.","year":"1986","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bmb.a071844"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(85)80254-4"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(87)80343-5"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1981.03320070042022"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.159.1.3513249"},{"key":"e_1_2_1_12_1","first-page":"321","article-title":"Antenatal detection of hydrops fetalis by sonography: hemoglobin Bart's as a major etiological factor in Taiwan","volume":"5","author":"Chen H Y.","year":"1984","journal-title":"J Echog Med Ultrasound"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1985.tb03070.x"},{"key":"e_1_2_1_14_1","first-page":"15","article-title":"Abnormal pregnancy sonogram: Selective indication for fetal karyotype","volume":"69","author":"Williamson R A.","year":"1987","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1001\/jama.1976.03270140023016","article-title":"Midtrimester amniocentesis for prenatal diagnosis. 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