{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T06:44:01Z","timestamp":1697957041671},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":8045,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1989,1]]},"abstract":"<jats:p>A total of 323 pairs of specimens from women with Papanicolau class II or III cytology were examined for human papillomavirus (HPV) types 6, 11, 16 and 18 by spot hybridization. Each pair consisted of a representative biopsy specimen and a smear specimen from cervical, vaginal or, more rarely, vulvar lesions. We found a close correlation between HPV findings in biopsies and smears. In 83.9% (271) of the cases, both specimens were either positive for a given HPV type or negative. No discordant HPV\u2010types in the two types of specimens were found. In 15.8% (51) of the cases, one specimen proved positive for a given HPV\u2010type while the other specimen from the same patient was negative. In 8.0% (26) of the cases, the biopsy specimen proved positive and the corresponding smear specimen was negative. On the other hand, in 7.7% (25) of the cases we were able to detect HPV DNA in the smear specimen, whereas the corresponding biopsy specimen was negative. We suggest that a smear specimen would be advantageous for screening large groups of patients for the presence of a HPV infection in the genital tract. By using smear specimens together with biopsy specimens it is possible to maximize the number of HPV infection diagnoses.<\/jats:p>","DOI":"10.3109\/00016348909013282","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:07:02Z","timestamp":1194980822000},"page":"627-631","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of Smear Specimens with Biopsy Specimens in a Nucleic Acid Hybridization Test for Human Papilloma Virus (HPV) Infection"],"prefix":"10.1111","volume":"68","author":[{"given":"Eeva","family":"Auvinen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veijo","family":"Hukkanen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorma","family":"Lehmijoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuula","family":"Salmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pertti","family":"Arstila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/321246a0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.12.3812"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1984.tb01944.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.2.560"},{"key":"e_1_2_1_6_1","first-page":"671","article-title":"Oncogenic association of specific human papillomavirus types with cervical neoplasia","volume":"79","author":"Lorincz A T.","year":"1987","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910410109"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1985.tb03019.x"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91072-5"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-66-7-1515"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-65-11-2003"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.16.5540"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(85)90164-3"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1128\/jvi.58.3.979-982.1986","article-title":"Cloning of monomeric human papillomavirus type 16 DNA integrated within cell DNA from a cervical carcinoma","volume":"58","author":"Matsukura T.","year":"1986","journal-title":"J Virol"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/314111a0"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.61.4.1061-1066.1987"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.13.4680"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910370405"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-71097-1_2"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(78)90284-2"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.8.3683"},{"key":"e_1_2_1_22_1","first-page":"561","article-title":"Labeling deoxyribonucleic acids to high specific activity in vitro by nick translation with DNA polymerase I","volume":"174","author":"Rigby P W. 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