{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T07:42:05Z","timestamp":1698306125956},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,1,7]],"date-time":"2011-01-07T00:00:00Z","timestamp":1294358400000},"content-version":"vor","delay-in-days":7311,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1991,1]]},"abstract":"<jats:p>Cervical biopsy specimens were taken from 55 Pap\u2010smear\u2010negative women with external genital warts in order to diagnose a concomitant cervical <jats:italic>human papillomavirus<\/jats:italic> (HPV) infection. HPV\u2010DNA was demonstrated by in situ hybridization in 17 (31%) of the samples: HPV types 16\/18in9, HPV types 6\/11 in 5 and double infection (16\/18 and 6\/11) in 3. HPV\u2010DNA was found in 10 (43%) of 23 biopsy specimens with koilocytotic atypia and in 5 (29%) of 17 specimens showing chronic inflammatory reaction, whereas only 2 (13%) of 15 women with normal cervical histology had HPV\u2010DNA in the biopsy specimen. Overall histology and in situ hybridization indicated the presence of a cervical HPV infection in at least 30 (55%) of the 55 women examined. Colposcopic examination revealed abnormal acetowhite epithelium in 17 (74%) of 23 women with koilocytosis and\/or HPV\u2010DNA positivity, compared with 7 (32%) of 22 HPV\u2010DNA\u2010negative women with histology showing either chronic inflamatory changes or normal epithelium <jats:italic>(p<\/jats:italic> &lt; 0.01). It is concluded that a cervical focus of HPV infection is frequent among Pap\u2010smear\u2010negative women with external genital warts.<\/jats:p>","DOI":"10.3109\/00016349109006181","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:07:57Z","timestamp":1194980877000},"page":"69-71","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Human papillomavirus types in cervical biopsy specimens from Pap\u2010smear\u2010negative women with external genital warts"],"prefix":"10.1111","volume":"70","author":[{"given":"Carsten Sand","family":"Petersen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Lindeberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik Klem","family":"Thomsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.12.3812"},{"key":"e_1_2_1_3_1","first-page":"601","article-title":"The predominance of human papillomavirus type 16 in vulvar neoplasia","volume":"71","author":"Buscema J.","year":"1988","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0306-3356(21)00106-0","article-title":"Squamous neoplasia of the cervix in relation to other genital tract neoplasia","volume":"12","author":"Campion M J.","year":"1985","journal-title":"Clinics Obstetrics Gynecology"},{"key":"e_1_2_1_5_1","first-page":"476","article-title":"Noncondylomatous cervical warts virus infection","volume":"55","author":"Reid R.","year":"1980","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1990.tb00485.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.298.6665.14"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199007000-00005"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016349109006181","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016349109006181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T00:45:52Z","timestamp":1698021952000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016349109006181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1991,1]]}},"alternative-id":["10.3109\/00016349109006181"],"URL":"https:\/\/doi.org\/10.3109\/00016349109006181","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,1]]},"assertion":[{"value":"2011-01-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}