{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T16:09:32Z","timestamp":1732032572929},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,1,7]],"date-time":"2011-01-07T00:00:00Z","timestamp":1294358400000},"content-version":"vor","delay-in-days":6915,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1992,2]]},"abstract":"<jats:p>The detectability of human papillomavirus DNA from cervical smears was studied by DNA tests of varying sensitivity. The results were correlated with cervical cytologic abnormalities. A total of 326 women examined at the gynecological outpatient clinics of five Scandinavian hospitals were enrolled in the study on the basis of previous pathological cervical smear or clinically suspected human papillomavirus (HPV) infection. The cervical smears were examined for HPV\u2010DNA of types 6\/11, 16 or 18 by two direct DNA tests, the AffiProbe HPV test and the ViraType test. The proportion of HPV\u2010DNA\u2010positive women with normal cytology, benign atypia (mild nuclear and cytoplasmic changes without signs of dysplasia) and dyskaryosis were 16% (12\/77), 27% (42\/156) and 37% (30\/81), respectively. The smears negative for HPV types 6\/11, 16 or 18 and those yielding discrepant results in the two commercial tests were also analysed by the polymerase chain reaction (PCR) method. By PCR analysis, the HPV 6\/11, 16 or 18 DNA positivity increased from 27% to 41%. The increase was particularly pronounced among the women with dyskaryosis in cytology.<\/jats:p>","DOI":"10.3109\/00016349209007964","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:09:03Z","timestamp":1194980943000},"page":"98-103","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Polymerase chain reaction and direct DNA tests in detection of human papillomavirus (HPV) DNA in cytologically normal and abnormal cervical smears: From the Scandinavian Multicenter Study Group"],"prefix":"10.1111","volume":"71","author":[{"name":"SCANDINAVIAN MULTICENTER STUDY GROUP","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arja","family":"Kallio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,7]]},"reference":[{"key":"e_1_2_2_2_1","first-page":"257","volume-title":"Papillomaviruscs and human disease","author":"Koss LG","year":"1987"},{"key":"e_1_2_2_3_1","first-page":"4677","article-title":"Papillomaviruscs in anogenital cancer as a model to understand the role of viruses in human cancers","volume":"49","author":"Hausen H.","year":"1989","journal-title":"Cancer Res"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.298.6665.14"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890270413"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)92067-2"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890210410"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/icb.1987.9"},{"key":"e_1_2_2_9_1","first-page":"554","article-title":"Human papillomaviruses in women with a history of abnormal Papanicolaou smears and in their male partners","volume":"69","author":"Schneider A.","year":"1987","journal-title":"Obstet Gynecol"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91072-5"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711530206"},{"key":"e_1_2_2_12_1","first-page":"508","article-title":"Correlation of cellular atypia and human papillomavirus deoxyribonucleic acid sequences in exfoliated cells of the uterine cervix","volume":"68","author":"Lorinez A T.","year":"1986","journal-title":"Obstet Gynecol"},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.293.6557.1261"},{"key":"e_1_2_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)90353-9"},{"key":"e_1_2_2_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840060313"},{"key":"e_1_2_2_16_1","first-page":"307","article-title":"The biology and significance of human papillomavirus infections in the genital tract","volume":"61","author":"Reid R.","year":"1988","journal-title":"Yale J Biol Med"},{"key":"e_1_2_2_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890320103"},{"key":"e_1_2_2_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.28.12.2739-2743.1990"},{"key":"e_1_2_2_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)90974-C"},{"key":"e_1_2_2_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.2.2.166"},{"key":"e_1_2_2_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(88)90906-3"},{"key":"e_1_2_2_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890320105"},{"key":"e_1_2_2_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890270207"},{"key":"e_1_2_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0890-8508(90)90056-6"},{"key":"e_1_2_2_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0890-8508(90)90025-U"},{"key":"e_1_2_2_26_1","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1128\/jcm.28.9.2076-2081.1990","article-title":"Use of Affi Probe HPV test kit for detection of human papillomavirus DNA in genital scrapes","volume":"28","author":"Ranki M.","year":"1990","journal-title":"J Clin Microbiol"},{"key":"e_1_2_2_27_1","first-page":"209","article-title":"Use of polymerase chain reaction amplification for the detection of genital human papillomaviruses","volume":"7","author":"Manos M M.","year":"1989","journal-title":"Cancer Cells"},{"key":"e_1_2_2_28_1","first-page":"26","article-title":"Cytology of gynecologic condyloma acuminatum","volume":"21","author":"Purola E.","year":"1977","journal-title":"Acta Cytol"},{"key":"e_1_2_2_29_1","first-page":"505","article-title":"Condylomatous lesions of the cervix and vagina. 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