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In 61 cases exchange transfusion of the newborn was needed and in 115 cases diagnostic amniocentesis was done during pregnancy. Intrauterine transfusions were performed in 10 cases. Fetal and neonatal mortality was 4% in these moderate to severe cases, all due to immunization against D. Immunization against D was due to failure to give immunoglobulin anti\u2010D in about 2\/3 of the cases. Systematic prophylactic treatment with anti\u2010D during pregnancy would probably not be cost\u2010effective in this population.<\/jats:p>","DOI":"10.3109\/00016349209021051","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T19:09:19Z","timestamp":1194980959000},"page":"273-277","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Allo\u2010immunization during pregnancy: Clinical results from 1983 to 1989 in a Scandinavian University Hospital"],"prefix":"10.1111","volume":"71","author":[{"given":"Patrick","family":"Belfrage","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Thomassen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Floberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olof","family":"\u00c5kerblom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Broberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-43-11151"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.1964.tb02824.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5365.1107"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.284.6313.373"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)36265-2"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/0002-9378(81)90083-1","article-title":"Rh isoimmunization: A 24 ycar cxperience at Duke University Medical Center","volume":"140","author":"Gall S.","year":"1981","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_8_1","first-page":"613","volume-title":"Maternal\u2010fetal medicine","author":"Bowman J.","year":"1989"},{"issue":"274","key":"e_1_2_1_9_1","article-title":"Prevention of Rh immunization in Finland. 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