{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:56:14Z","timestamp":1757703374895},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,1,7]],"date-time":"2011-01-07T00:00:00Z","timestamp":1294358400000},"content-version":"vor","delay-in-days":5760,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1995,4]]},"abstract":"<jats:p><jats:italic>Background.<\/jats:italic> In ovum donation programs oocytes can be requested from infertile women going through an <jats:italic>in vitro<\/jats:italic> fertilization cycle. Currently, when embryos can be cryopreserved, these donors have virtually disappeared. Instead, most donors have been healthy fertile volunteers willing to go through an IVF attempt solely for the purpose of donating all oocytes.<\/jats:p><jats:p><jats:italic>Methods.<\/jats:italic> Sixty\u2010four patients had 93 started cycles of oocyte donation from 59 donors. Twenty recipients had primary ovarian failure, 24 had secondary ovarian failure, 15 had had repeated failures in earlier IVF attempts and five were carriers of genetic diseases. The donors were 51 healthy volunteers recruited through the press. Eight patients from an IVF program donated excess oocytes. Donors were not paid and their mean age was 30 years. To minimize discomfort of the treatment, a long\u2010acting GnRH\u2010agonist, goserelin, was used for down\u2010regulation.<\/jats:p><jats:p><jats:italic>Results.<\/jats:italic> The pregnancy rate per transfer with fresh embryos was 28.4% (23\/81) and with frozen\u2010thawed embryos, 17% (3\/18). Twenty\u2010one healthy infants have been born including one set of triplets and three sets of twins. Nine pregnancies ended in abortion and one in intrauterine fetal death. The most common complications of pregnancy were pre\u2010eclampsia and pregnancy\u2010induced hypertension (41.2%, 7\/17). Ten of 17 patients delivered by cesarean section (58.8%).<\/jats:p><jats:p><jats:italic>Conclusion.<\/jats:italic> It was possible, through the press, to obtain highly motivated oocyte donors, who go through IVF treatment solely for altruistic reasons. Oocyte recipients appear to have many complications in their pregnancies. Until more data are available, these patients need a high standard of obstetric care.<\/jats:p>","DOI":"10.3109\/00016349509024451","type":"journal-article","created":{"date-parts":[[2007,11,22]],"date-time":"2007-11-22T00:47:04Z","timestamp":1195692424000},"page":"288-292","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["An oocyte donation program with goserelin down\u2010regulation of voluntary donors"],"prefix":"10.1111","volume":"74","author":[{"given":"Viveca","family":"S\u00f6derstrom\u2010Anttila","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Outi","family":"Hovatta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/307174a0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/3.suppl_2.85"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)92762-1"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1093\/oxfordjournals.humrep.a137209","article-title":"A report on 100 cycles of oocyte donation factors affecting the outcome","volume":"5","author":"Abdalla H. J.","year":"1990","journal-title":"Hum Reprod"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90427-Q"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01203958"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a137980"},{"key":"e_1_2_1_9_1","volume-title":"Medstat, statistical program for the analysis of the results of controlled therapeutic trials and other types of clinical research","author":"Wulff H. R.","year":"1991"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1991.tb37936.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90132-Z"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)93060-M"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/oxfordjournals.humrep.a137649","article-title":"Comparison of attitudes of donors and recipients to oocyte donation","volume":"7","author":"Kirkland A.","year":"1992","journal-title":"Hum Reprod"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)60913-5"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1093\/oxfordjournals.humrep.a137326","article-title":"A comparison of pregnancy rates for 131 donor oocyte transfers using either a sequental or fixed regime of steroid replacement therapy","volume":"6","author":"Leeton J.","year":"1991","journal-title":"Hum Reprod"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a137138"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)55617-9"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a138509"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a138541"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016349509024451","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016349509024451","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T17:41:13Z","timestamp":1698255673000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016349509024451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,4]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,4]]}},"alternative-id":["10.3109\/00016349509024451"],"URL":"https:\/\/doi.org\/10.3109\/00016349509024451","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,4]]},"assertion":[{"value":"2011-01-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}