{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T12:56:17Z","timestamp":1781614577474,"version":"3.54.5"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,1,7]],"date-time":"2011-01-07T00:00:00Z","timestamp":1294358400000},"content-version":"vor","delay-in-days":5425,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1996,3]]},"abstract":"<jats:p><jats:bold><jats:italic>Objective<\/jats:italic><\/jats:bold> To determine whether lipid alterations in hirsute women are due to excessive androgen, low estrogen or to a combination of these abnormalities. Design. Cross sectional study.<\/jats:p><jats:p><jats:bold><jats:italic>Patients<\/jats:italic><\/jats:bold> Forty\u2010five hirsute women between 15 and 39 years of age.<\/jats:p><jats:p><jats:bold><jats:italic>Main outcome measures<\/jats:italic><\/jats:bold> FSH, LH, 17\u03b2\u2010estradiol, PRL, testosterone, androstenedione, DHEAS, 17\u2010OH\u2010progesterone, sex hormone binding globulin, cholesterol, LDL, HDL, triglycerides, and apolipoproteins A\u2010I and B.<\/jats:p><jats:p><jats:bold><jats:italic>Results<\/jats:italic><\/jats:bold> Testosterone was correlated with triglycerides (<jats:italic>r<\/jats:italic>: 0.76, <jats:italic>p<\/jats:italic> &lt; 0.01), HDL (<jats:italic>r<\/jats:italic>: \u22120.61, <jats:italic>p<\/jats:italic> &lt; 0.01) and LDL (<jats:italic>r<\/jats:italic>: 0.50, <jats:italic>p<\/jats:italic> &lt; 0.05). Both HDL (<jats:italic>r<\/jats:italic>: 0.66, <jats:italic>p<\/jats:italic> &lt; 0.01) and LDL (<jats:italic>r<\/jats:italic>: \u22120.57, <jats:italic>p<\/jats:italic> &lt; 0.01) were correlated with estradiol. Total cholesterol was also correlated with estradiol (<jats:italic>r<\/jats:italic>: \u22120.52, <jats:italic>p<\/jats:italic> &lt; 0.05). Cross adjusted correlations revealed that, after adjusting for estradiol, lipids were associated with testosterone and that estradiol was also correlated with lipids when adjusted for testosterone.<\/jats:p><jats:p><jats:bold><jats:italic>Conclusion<\/jats:italic><\/jats:bold> The results suggest that altered lipids in women with hyperandrogenism could result from independent effects of androgens and estrogens.<\/jats:p>","DOI":"10.3109\/00016349609047098","type":"journal-article","created":{"date-parts":[[2007,11,22]],"date-time":"2007-11-22T00:48:24Z","timestamp":1195692504000},"page":"261-265","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Plasma lipids, lipoproteins and apolipoproteins in hirsute women"],"prefix":"10.1111","volume":"75","author":[{"given":"Camil","family":"Castelo\u2010Branco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Casals","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J. 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