{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:44:51Z","timestamp":1759563891138,"version":"3.41.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[1997,8,31]],"date-time":"1997-08-31T00:00:00Z","timestamp":872985600000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1997,8]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic> To assess the risk of ectopic pregnancy when using copper intrauterine devices relative to non\u2010use of coniraception and female sterilization.<\/jats:p><jats:p><jats:italic>Design.<\/jats:italic> Case\u2010control study.<\/jats:p><jats:p><jats:italic>Material and methods.<\/jats:italic> All cases diagnosed with a histologically verified extrauterine pregnancy and who became spontaneously pregnant in one Norwegian county from January 1, 1987 through to December 31, 1990 were eligible. Non\u2010pregnant control women were chosen at random from the Norwegian Population Registry. Eligible for study were sexually active women, from 20 to 39 years of age, and who defined themselves as fecund. Included in the final analyses were 168 cases and 1,169 controls, who had all been previously pregnant. <jats:italic>Statistical methods.<\/jats:italic> Chi square test and unconditional logistic regression.<\/jats:p><jats:p><jats:italic>Results.<\/jats:italic> Compared with non\u2010users of contraception, the adjusted odds ratio (aOR) among current users of copper intrauterine devices was 0.09 (95% confidence intervals (CI); 0.06 0.13). Compared with women who were sterilized, the aOR of having an ectopic pregnancy among current copper IUD users was 1.6 (95% CI; 0.7\u20103.5).<\/jats:p><jats:p><jats:italic>Conclusion.<\/jats:italic> Relative to non\u2010users of contraception, current copper IUD users had a 91% (95% CI; 87\u201094%) protection against ectopic pregnancy, while compared with women who had had a tubal sterilization, current copper IUD users had a 60% non\u2010significant increased risk of ectopic pregnancy.<\/jats:p>","DOI":"10.3109\/00016349709024611","type":"journal-article","created":{"date-parts":[[2008,3,13]],"date-time":"2008-03-13T13:06:22Z","timestamp":1205413582000},"page":"684-690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["How effectively do copper intrauterine devices prevent ectopic pregnancy?"],"prefix":"10.1111","volume":"76","author":[{"given":"Finn Egil","family":"Skjeldestad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1997,8,31]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"21","article-title":"Increase of ectopic pregnancy in Finland Combination of time and cohort effects","volume":"73","author":"M\u00e4kinen J. 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