{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T21:40:19Z","timestamp":1777412419766,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1996,8,1]],"date-time":"1996-08-01T00:00:00Z","timestamp":838857600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust N Z J Psychiatry"],"published-print":{"date-parts":[[1996,8]]},"abstract":"<jats:p>Objective: There are reports of alprazolam-induced hypomania\/mania. Here is a case report of a patient who developed hypomania during treatment with alprazolam, but not with diazepam, another benzodiazepine derivative. Clinical picture: The illness was of 2 months' duration and the patient received a diagnosis of anxious depression. Following treatment with alprazolam, the patient developed hypomania characterised by euphoria, overactivity, overtalkativity, racing thoughts, oversocialisation, enhanced self-confidence and disturbed sleep.<\/jats:p>\n                  <jats:p>Treatment: Hypomania subsided when alprazolam was withdrawn. There was no recurrence with fluoxetine or diazepam that ameliorated the primary condition.<\/jats:p>\n                  <jats:p>Outcome: The patient was symptom-free on follow-up.<\/jats:p>\n                  <jats:p>Conclusions: Alprazolam can induce hypomania\/mania and, perhaps, it differs from other benzodiazepines in its mode of action. Clinicians have to be alert to the possibility of their patients developing hypomania\/mania while on alprazolam.<\/jats:p>","DOI":"10.3109\/00048679609065031","type":"journal-article","created":{"date-parts":[[2007,11,21]],"date-time":"2007-11-21T20:55:48Z","timestamp":1195678548000},"page":"550-552","source":"Crossref","is-referenced-by-count":7,"title":["Alprazolam-Induced Hypomania"],"prefix":"10.1177","volume":"30","author":[{"given":"Janardhan Y.C.","family":"Reddy","sequence":"first","affiliation":[{"name":"Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumant","family":"Khanna","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uday","family":"Anand","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amiya","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,8,1]]},"reference":[{"key":"bibr1-00048679609065031","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1988.01800290027004"},{"key":"bibr2-00048679609065031","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.160.2.191"},{"key":"bibr3-00048679609065031","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1993.01820130053009"},{"key":"bibr4-00048679609065031","first-page":"347","volume":"42","author":"Cohn JB.","year":"1981","journal-title":"Journal of Clinical Psychiatry"},{"key":"bibr5-00048679609065031","doi-asserted-by":"publisher","DOI":"10.1007\/BF03259411"},{"key":"bibr6-00048679609065031","doi-asserted-by":"publisher","DOI":"10.1007\/BF02244440"},{"key":"bibr7-00048679609065031","volume-title":"Psychopharmacology: a generation of progress","author":"Bunney WE.","year":"1978"},{"key":"bibr8-00048679609065031","first-page":"49","volume":"54","author":"Cole JO","year":"1993","journal-title":"Journal of Clinical Psychiatry"},{"key":"bibr9-00048679609065031","volume-title":"The ICD-10 classification of mental and behavioural disorders. Clinical descriptions and diagnostic guidelines","author":"World Health Organization.","year":"1992"},{"key":"bibr10-00048679609065031","first-page":"117","volume":"48","author":"Goodman WK","year":"1987","journal-title":"Journal of Clinical Psychiatry"},{"key":"bibr11-00048679609065031","doi-asserted-by":"publisher","DOI":"10.1007\/BF00652229"},{"key":"bibr12-00048679609065031","unstructured":"Sethy VH, Hodges DH. Antidepressant activity of alprazolam and adinazolam in reserpine-induced model of depression. Presented at the 14th Congress of the College of International Neuropsychopharmacology. Florence, Italy, 1984."},{"key":"bibr13-00048679609065031","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(84)90247-4"}],"container-title":["Australian &amp; New Zealand Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3109\/00048679609065031","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3109\/00048679609065031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:50:47Z","timestamp":1777373447000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3109\/00048679609065031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,8]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,8]]}},"alternative-id":["10.3109\/00048679609065031"],"URL":"https:\/\/doi.org\/10.3109\/00048679609065031","relation":{},"ISSN":["0004-8674","1440-1614"],"issn-type":[{"value":"0004-8674","type":"print"},{"value":"1440-1614","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,8]]}}}