{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T21:40:18Z","timestamp":1777412418949,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1996,8,1]],"date-time":"1996-08-01T00:00:00Z","timestamp":838857600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust N Z J Psychiatry"],"published-print":{"date-parts":[[1996,8]]},"abstract":"<jats:p>Objective: A case of XXYY associated with schizophrenia is presented. Clinical picture: A European male with tall stature, hypogonadism, and mild grade intellectual handicap with significantly lower verbal than performance Intelligence Quotient (IQ) exhibited features of chronic paranoid schizophrenia, along with impulsive aggression.<\/jats:p>\n                  <jats:p>Treatment and outcome: A trial of testosterone replacement exacerbated aggression. Psychotic symptoms persisted despite antipsychotic therapy. Conclusions: This is perhaps the first report of the XXYY syndrome associated with schizophrenia. The psychosis occurs more often in XXY and XXX than normal subjects, providing a clue to locating a gene predisposing to schizophrenia.<\/jats:p>","DOI":"10.3109\/00048679609065032","type":"journal-article","created":{"date-parts":[[2007,11,21]],"date-time":"2007-11-21T20:55:49Z","timestamp":1195678549000},"page":"553-556","source":"Crossref","is-referenced-by-count":12,"title":["An XXYY Male with Schizophrenia"],"prefix":"10.1177","volume":"30","author":[{"given":"Joseph W.Y.","family":"Lee","sequence":"first","affiliation":[{"name":"Graylands Hospital, Mt Claremont, Western, Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,8,1]]},"reference":[{"key":"bibr1-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(60)91624-X"},{"key":"bibr2-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1970.tb02248.x"},{"key":"bibr3-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(70)80013-4"},{"key":"bibr4-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.153.5.675"},{"key":"bibr5-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1970.tb02102.x"},{"key":"bibr6-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1016\/0093-934X(82)90005-0"},{"key":"bibr7-00048679609065032","first-page":"99","volume":"18","author":"Steward DA","year":"1982","journal-title":"Birth Defects: Original Article Series"},{"key":"bibr8-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2626(87)90116-3"},{"key":"bibr9-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1984.01790120097012"},{"key":"bibr10-00048679609065032","first-page":"809","volume":"52","author":"Bernstein R","year":"1977","journal-title":"South Africa Medical Journal"},{"key":"bibr11-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1991.tb03051.x"},{"key":"bibr12-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1177\/070674378803300912"},{"key":"bibr13-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700044111"},{"key":"bibr14-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.126.6.814"},{"key":"bibr15-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.1982.tb02281.x"},{"key":"bibr16-00048679609065032","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association.","year":"1994","edition":"4"},{"key":"bibr17-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1177\/070674378202700204"},{"key":"bibr18-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1037\/h0046051"},{"key":"bibr19-00048679609065032","volume-title":"Schizophrenia, the epigenetic puzzle","author":"Gottesman I","year":"1982"},{"key":"bibr20-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/20.3.495"},{"key":"bibr21-00048679609065032","first-page":"89","volume":"2","author":"Kaplan AR.","year":"1970","journal-title":"Biological Psychiatry"},{"key":"bibr22-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.161.3.323"},{"key":"bibr23-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320540108"},{"key":"bibr24-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.164.2.159"},{"key":"bibr25-00048679609065032","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/20.2.277"}],"container-title":["Australian &amp; New Zealand Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3109\/00048679609065032","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3109\/00048679609065032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:50:47Z","timestamp":1777373447000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3109\/00048679609065032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,8]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,8]]}},"alternative-id":["10.3109\/00048679609065032"],"URL":"https:\/\/doi.org\/10.3109\/00048679609065032","relation":{},"ISSN":["0004-8674","1440-1614"],"issn-type":[{"value":"0004-8674","type":"print"},{"value":"1440-1614","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,8]]}}}