{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:01:21Z","timestamp":1761919281115},"reference-count":99,"publisher":"Informa UK Limited","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Neuroscience"],"published-print":{"date-parts":[[1996,1]]},"DOI":"10.3109\/00207459608986695","type":"journal-article","created":{"date-parts":[[2009,12,7]],"date-time":"2009-12-07T22:59:46Z","timestamp":1260226786000},"page":"23-31","source":"Crossref","is-referenced-by-count":18,"title":["Estrogen's Impact on Cognitive Functions in Multiple Sclerosis"],"prefix":"10.1080","volume":"86","author":[{"given":"Reuven","family":"Sandyk","sequence":"first","affiliation":[{"name":"NeuroCommunication Research Laboratories, 36 Mill Plain Road, Danbury, CT, 06811, USA"},{"name":"Department of Neuroscience, Institute for Biomedical Engineering and Rehabilitation Services of Touro College, Dix Hills, NY, 11746, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,7]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1002\/ana.410360712","volume":"36","author":"Abramsky O","year":"1994","journal-title":"Annals of Neurology"},{"key":"CIT0002","first-page":"141","volume-title":"Psychopharmacology: the third generation of progress","author":"Aghajanian G. K.","year":"1987"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1126\/science.2580352","volume":"228","author":"Altar C. A.","year":"1985","journal-title":"Science"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/BF00172866","volume":"90","author":"Altman H. J.","year":"1986","journal-title":"Psychopharmacology"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/S0197-4580(88)80124-6","volume":"9","author":"Altman H. J.","year":"1988","journal-title":"Neurobiology of Aging"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0304-3940(81)90104-X","volume":"25","author":"Archer T.","year":"1981","journal-title":"Neuroscience Letters"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1055\/s-2007-1017361","volume":"18","author":"Baumgarten H. G.","year":"1985","journal-title":"Pharmacopsychiatrie"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2626(89)90006-7"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/0028-3908(77)90117-4","volume":"16","author":"Bedard P.","year":"1977","journal-title":"Neuropharmacology"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3932(68)90038-9"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0006-8993(80)90509-0","volume":"187","author":"Biegon A.","year":"1980","journal-title":"Brain Research"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1016\/0024-3205(83)90053-X","volume":"32","author":"Biegon A.","year":"1983","journal-title":"Life Sciences"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1001\/archneur.1986.00520070075022","volume":"43","author":"Birk K.","year":"1986","journal-title":"Archives of Neurology"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1990.00530070026007"},{"key":"CIT0015","first-page":"634","volume":"45","author":"Birner I. M","year":"1945","journal-title":"New York State Journal of Medicine"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1600-0773.1988.tb00930.x","volume":"63","author":"Brunello N.","year":"1988","journal-title":"Pharmacology and Toxicology"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0165-6147(87)90101-5","volume":"8","author":"Chopin P.","year":"1987","journal-title":"Trends in Pharmacological Sciences"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1136\/jnnp.37.6.715","volume":"37","author":"Claveria L. E.","year":"1974","journal-title":"Journal of Neurology, Neurosurgery and Psychiatry"},{"key":"CIT0019","unstructured":"Comings D. E. Tourette syndrome and human behavior. Hope Press, Duarte, CA 1990; 341\u2013361"},{"key":"CIT0020","first-page":"147","volume-title":"Serotonin, CNS receptors and brain function","author":"Costall B.","year":"1992"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1192\/S0007125000296190","volume":"159","author":"Cowen P. J","year":"1991","journal-title":"British Journal of Psychiatry"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1111\/j.1471-4159.1984.tb06081.x","volume":"43","author":"Cross A. J.","year":"1984","journal-title":"Journal of Neurochemistry"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1136\/jnnp.40.8.741","volume":"40","author":"Davidson D.","year":"1977","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/00006254-199205000-00002","volume":"47","author":"Davis R. K.","year":"1992","journal-title":"Obstetrics and Gynecological Survey"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3758\/BF03326704","volume":"6","author":"Dickey R. P.","year":"1978","journal-title":"Physiological Psychology"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/0306-4530(94)90019-1","volume":"19","author":"Dow R. C.","year":"1994","journal-title":"Psychoneuroendocrinology"},{"key":"CIT0027","first-page":"195","volume":"6","author":"Duquette P.","year":"1993","journal-title":"Current Opinion in Neurology and Neurosurgery"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1017\/S0317167100041664","volume":"19","author":"Duquette P.","year":"1992","journal-title":"Canadian Journal of Neurological Sciences"},{"key":"CIT0029","first-page":"311","volume":"26","author":"Eisen A. S.","year":"1990","journal-title":"Psychopharmacology Bulletin"},{"key":"CIT0030","first-page":"49","volume":"26","author":"Fahn S","year":"1979","journal-title":"Advances in Neurology"},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1126\/science.6623080","volume":"222","author":"Fischette C. T.","year":"1983","journal-title":"Science"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1093\/oxfordjournals.aje.a113188","volume":"114","author":"Fischman H. R","year":"1981","journal-title":"American Journal of Epidemiology"},{"key":"CIT0033","first-page":"1154","volume-title":"Neurology in clinical practice","author":"Francis G. S.","year":"1990"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1001\/archneur.1989.00520380066014","volume":"46","author":"Franklin G. M.","year":"1989","journal-title":"Archives of Neurology"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/00004714-199406000-00005","volume":"14","author":"Freeman E. W.","year":"1994","journal-title":"Journal of Clinical Psychopharmacology"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1159\/000115217","volume":"20","author":"Ghezzi A.","year":"1981","journal-title":"European Neurology."},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0149-7634(05)80158-7","volume":"14","author":"Glennon R. A","year":"1990","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0006-8993(90)90081-L","volume":"519","author":"Gross-Isseroff R.","year":"1990","journal-title":"Brain Research"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4530(90)90018-5"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1192\/bjp.164.3.288","volume":"164","author":"Harris B","year":"1994","journal-title":"British Journal of Psychiatry"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.53.1.103"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000114304","volume":"11","author":"Johansson B.","year":"1977","journal-title":"European Neurology"},{"key":"CIT0043","volume-title":"Basic histology, 4th ed","author":"Junquiera L. C.","year":"1983"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1126\/science.6258229","volume":"211","author":"Kendall D. A.","year":"1981","journal-title":"Science"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/ana.410160211","volume":"16","author":"Kom-Lubetzki I.","year":"1984","journal-title":"Annals of Neurology"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1159\/000122536","volume":"21","author":"Kueng W.","year":"1976","journal-title":"Neuroendocrinology"},{"key":"CIT0047","doi-asserted-by":"crossref","first-page":"567","DOI":"10.3928\/0048-5713-19901001-07","volume":"20","author":"Lawlor B. A","year":"1990","journal-title":"Psychiatric Annals"},{"key":"CIT0048","first-page":"12","volume":"49","author":"Leonard B. E","year":"1988","journal-title":"Journal of Clinical Psychiatry"},{"key":"CIT0049","first-page":"139","volume":"61","author":"Leysen J","year":"1983","journal-title":"Medical Biology"},{"key":"CIT0050","first-page":"79","volume-title":"Neuropharmacology of serotonin","author":"Leysen J. E","year":"1985"},{"key":"CIT0051","first-page":"153","volume":"24","author":"Luga N.","year":"1986","journal-title":"Review Roumanian Medicine\u2013Neurology and Psychiatry"},{"key":"CIT0052","first-page":"68","volume":"33","author":"Magos A.","year":"1985","journal-title":"British Journal of Hospital Medicine"},{"key":"CIT0053","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/BF00314354","volume":"235","author":"Markianos M.","year":"1988","journal-title":"Journal of Neurology"},{"key":"CIT0054","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1002\/mds.870030308","volume":"3","author":"Mayeux R.","year":"1988","journal-title":"Movement Disorders"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1600-0404.1969.tb01229.x","volume":"45","author":"McCall M.","year":"1969","journal-title":"Acta Neurologica Scandinavica"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1007\/BF02244194"},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/ana.410070513","volume":"7","author":"McEntee W. J.","year":"1980","journal-title":"Annals of Neurology"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410190403"},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/brain\/82.3.417","volume":"82","author":"Millar J. H. D.","year":"1959","journal-title":"Brain"},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1136\/jnnp.42.7.640","volume":"42","author":"Monaco F.","year":"1979","journal-title":"Journal of Neurology, Neurosurgery and Psychiatry"},{"key":"CIT0061","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/0306-4522(93)90241-7","volume":"54","author":"Morilak D. A.","year":"1993","journal-title":"Neuroscience"},{"key":"CIT0062","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1159\/000122782","volume":"26","author":"Munaro N. I","year":"1978","journal-title":"Neuroendocrinology"},{"key":"CIT0063","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0006-8993(88)90163-1","volume":"453","author":"Nilsson O. G.","year":"1988","journal-title":"Brain Research"},{"key":"CIT0064","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0006-8993(84)91459-8","volume":"293","author":"O'Connor L. H.","year":"1984","journal-title":"Brain Research"},{"key":"CIT0065","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0006-8993(85)90857-1","volume":"346","author":"Pazos A.","year":"1985","journal-title":"Brain Research"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1126\/science.7221567","volume":"212","author":"Peroutka S. J.","year":"1981","journal-title":"Science"},{"key":"CIT0067","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1176\/jnp.1.3.253","volume":"1","author":"Peroutka S. J.","year":"1989","journal-title":"Journal of Neuropsychiatry"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1990.00530010120030"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1212\/WNL.33.11.1422","volume":"33","author":"Poser S.","year":"1983","journal-title":"Neurology"},{"key":"CIT0070","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1097\/00002826-198506000-00001","volume":"8","author":"Pranzatelli M.","year":"1985","journal-title":"Clinical Neuropharmacology"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1984.04210080033010"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.55.2.263"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.5.685"},{"key":"CIT0074","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/0006-8993(89)91437-6","volume":"477","author":"Richter-Levin G.","year":"1988","journal-title":"Brain Research"},{"key":"CIT0075","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0009-8981(67)90161-1","volume":"18","author":"Rose D. P","year":"1967","journal-title":"Clinica Chimica Acta"},{"key":"CIT0076","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1037\/0735-7044.102.3.456","volume":"102","author":"Sampson E.","year":"1988","journal-title":"Behavioral Neuroscience"},{"key":"CIT0077","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3109\/00207459508986338","volume":"83","author":"Sandyk R","year":"1995","journal-title":"International Journal of Neuroscience"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/89.3.419"},{"key":"CIT0079","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0006-8993(83)90729-1","volume":"276","author":"Schotte A.","year":"1983","journal-title":"Brain Research"},{"key":"CIT0080","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/0006-8993(90)91199-Q","volume":"506","author":"Sheldon P. W.","year":"1990","journal-title":"Brain Research"},{"key":"CIT0081","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0301-0082(94)90060-4","volume":"43","author":"Silvio J.","year":"1994","journal-title":"Progress in Neurobiology"},{"key":"CIT0082","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1600-0404.1981.tb04392.x","volume":"64","author":"Soininen H.","year":"1981","journal-title":"Acta Neurologica Scandinavica"},{"key":"CIT0083","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1212\/WNL.23.7.760","volume":"23","author":"Sonninen V.","year":"1973","journal-title":"Neurology"},{"key":"CIT0084","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0140-6736(83)92590-4","volume":"1","author":"Stanley M.","year":"1983","journal-title":"Lancet"},{"key":"CIT0085","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0091-3057(89)90456-5","volume":"33","author":"Strek K. F.","year":"1989","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"CIT0086","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1006\/mcne.1993.1010","volume":"4","author":"Sumner B. E. H.","year":"1993","journal-title":"Molecular Cell Neuroscience"},{"key":"CIT0087","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0960-0760(95)00075-B","volume":"54","author":"Sumner B. E. H.","year":"1995","journal-title":"Journal of Steroid Biochemistry and Molecular Biology"},{"key":"CIT0088","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/0002-9378(53)90294-4","volume":"66","author":"Sweeney W. J","year":"1955","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"CIT0089","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1212\/WNL.28.12.1249","volume":"28","author":"Tabaddor K.","year":"1978","journal-title":"Neurology"},{"key":"CIT0090","first-page":"548","volume":"28","author":"Tillman A. J. B","year":"1950","journal-title":"Research Publications of the Association for Research in Nervous and Mental Disease"},{"key":"CIT0091","first-page":"44","volume":"12","author":"Wainerdi H. R","year":"1961","journal-title":"Boston Medical Quarterly"},{"key":"CIT0092","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/0014-2999(86)90596-0","volume":"132","author":"Wander T. J.","year":"1986","journal-title":"European Journal of Pharmacology"},{"key":"CIT0093","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0031-9384(78)90215-9","volume":"20","author":"Ward M. M.","year":"1978","journal-title":"Physiology and Behavior"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1126\/science.6223371"},{"key":"CIT0095","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0091-3057(80)90378-0","volume":"12","author":"Wetzel W.","year":"1980","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"CIT0096","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1176\/jnp.2.4.422","volume":"2","author":"White R. F","year":"1990","journal-title":"Journal of Neuropsychiatry"},{"key":"CIT0097","first-page":"189","volume-title":"Multiple sclerosis: current status of research and treatment","author":"Whitham R. H","year":"1994"},{"key":"CIT0098","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0014-2999(76)90349-6","volume":"40","author":"Wirz-Justice A.","year":"1976","journal-title":"European Journal of Pharmacology"},{"key":"CIT0099","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1210\/endo-70-2-196","volume":"70","author":"Woolley D. E.","year":"1962","journal-title":"Endocrinology"}],"container-title":["International Journal of Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/00207459608986695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T09:16:37Z","timestamp":1558689397000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3109\/00207459608986695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":99,"journal-issue":{"issue":"1-2","published-online":{"date-parts":[[2009,7,7]]},"published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.3109\/00207459608986695"],"URL":"https:\/\/doi.org\/10.3109\/00207459608986695","relation":{},"ISSN":["0020-7454","1543-5245"],"issn-type":[{"value":"0020-7454","type":"print"},{"value":"1543-5245","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]}}}