{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:25:01Z","timestamp":1770823501629,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1989,1,1]],"date-time":"1989-01-01T00:00:00Z","timestamp":599616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology"],"published-print":{"date-parts":[[1989]]},"DOI":"10.3109\/00313028909059522","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T11:57:01Z","timestamp":1196423821000},"page":"11-15","source":"Crossref","is-referenced-by-count":36,"title":["Immunoperoxidase staining in the detection of lymph node metastases in stage i breast cancer"],"prefix":"10.1016","volume":"21","author":[{"given":"Wendy A.","family":"Raymond","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony S-Y.","family":"Leong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.3109\/00313028909059522_bib0005","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1002\/1097-0142(19821115)50:10<2131::AID-CNCR2820501027>3.0.CO;2-A","article-title":"The pathologic findings of breast cancer in patients surviving 25 years after radical mastectomy","volume":"50","author":"Dawson","year":"1982","journal-title":"Cancer"},{"key":"10.3109\/00313028909059522_bib0010","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1002\/1097-0142(19820901)50:5<962::AID-CNCR2820500526>3.0.CO;2-X","article-title":"Blood vessel invasion and axillary lymph node involvement as prognostic indication for human breast cancer","volume":"50","author":"Weigand","year":"1982","journal-title":"Cancer"},{"key":"10.3109\/00313028909059522_bib0015","first-page":"839","article-title":"Axillary micrometastasis and macrometastasis in carcinoma of the breast","volume":"144","author":"Attiyeh","year":"1977","journal-title":"Surg Gynecol Obstet"},{"key":"10.3109\/00313028909059522_bib0020","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1002\/1097-0142(197810)42:4<2025::AID-CNCR2820420452>3.0.CO;2-J","article-title":"Detection and significance of occult axillary node metastases in patients with invasive breast cancer","volume":"42","author":"Fisher","year":"1978","journal-title":"Cancer"},{"key":"10.3109\/00313028909059522_bib0025","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1038\/bjc.1980.250","article-title":"The use of antisera to epithelial membrane antigen in detecting micrometastases in histological sections","volume":"42","author":"Sloane","year":"1980","journal-title":"Br J Cancer"},{"key":"10.3109\/00313028909059522_bib0030","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/bjc.1984.162","article-title":"The immunocytochemical detection of axillary micrometastases in breast cancer","volume":"50","author":"Wells","year":"1984","journal-title":"Br J Cancer"},{"key":"10.3109\/00313028909059522_bib0035","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/bjc.1986.219","article-title":"The immunohistochemical detection of lymph node metastases from infiltrating lobular carcinoma of the breast","volume":"54","author":"Bussolati","year":"1986","journal-title":"Br J Cancer"},{"key":"10.3109\/00313028909059522_bib0040","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/path.1711460404","article-title":"Microwave irradiation as a form of fixation for light and electron microscopy","volume":"146","author":"AS-Y","year":"1985","journal-title":"J Pathol"},{"key":"10.3109\/00313028909059522_bib0045","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3109\/00313028609059463","article-title":"A method of rapid fixation of large biopsy specimens using microwave irradiation","volume":"18","author":"AS-Y","year":"1986","journal-title":"Pathology"},{"key":"10.3109\/00313028909059522_bib0050","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0092-8674(82)90234-3","article-title":"Correlation of specific keratins with different types of epithelial differentiation: Monoclonal antibody studies","volume":"30","author":"Tseng","year":"1982","journal-title":"Cell"},{"key":"10.3109\/00313028909059522_bib0055","first-page":"243","article-title":"Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: Strategies, applications and limitation","volume":"52","author":"Cooper","year":"1985","journal-title":"Lab Invest"},{"key":"10.3109\/00313028909059522_bib0060","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0092-8674(82)90400-7","article-title":"The catalogue of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells","volume":"31","author":"Moll","year":"1982","journal-title":"Cell"},{"key":"10.3109\/00313028909059522_bib0065","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1136\/jcp.37.9.975","article-title":"Monoclonal antibody to cytokeratin for use in routine histopathology","volume":"37","author":"Makin","year":"1984","journal-title":"J Clin Pathol"},{"key":"10.3109\/00313028909059522_bib0070","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1136\/jcp.32.1.35","article-title":"A new antigen on the epithelial membrane: Its immunoperoxidase localization in normal and neoplastic tissue","volume":"32","author":"Heyderman","year":"1979","journal-title":"J Clin Pathol"},{"key":"10.3109\/00313028909059522_bib0075","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/path.1711480209","article-title":"Rapid immunoperoxidase staining of lymphocyte antigens using microwave irradiation","volume":"148","author":"AS-Y","year":"1986","journal-title":"J Pathol"},{"key":"10.3109\/00313028909059522_bib0080","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/bjc.1957.43","article-title":"Histologic grading and prognosis in breast cancer: A study of 1409 cases of which 359 have been followed for 15 years","volume":"11","author":"Bloom","year":"1957","journal-title":"Br J Cancer"},{"key":"10.3109\/00313028909059522_bib0085","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/S0140-6736(83)91150-9","article-title":"Detection of micrometastases in patients with primary breast cancer","volume":"2","author":"Redding","year":"1983","journal-title":"Lancet"},{"key":"10.3109\/00313028909059522_bib0090","first-page":"3079","article-title":"Potential pathological application of immunocytochemical methods to the detection of micrometastases","volume":"40","author":"Sloane","year":"1980","journal-title":"Cancer Res"},{"key":"10.3109\/00313028909059522_bib0095","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1093\/ajcp\/85.3.269","article-title":"Are keratin proteins a better tumor marker than epithelial membrane antigen?","volume":"85","author":"Pinkus","year":"1986","journal-title":"Am J Clin Pathol"},{"key":"10.3109\/00313028909059522_bib0100","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/S0046-8177(87)80244-7","article-title":"Keratins versus epithelial membrane antigen in tumor diagnosis: An immunohistocehmical comparison of five monoclonal antibodies","volume":"18","author":"Thomas","year":"1987","journal-title":"Hum Pathol"},{"key":"10.3109\/00313028909059522_bib0105","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/S0140-6736(84)91558-7","article-title":"Human lymphoid cells express epithelial membrane antigen","volume":"2","author":"Delsol","year":"1984","journal-title":"Lancet"},{"key":"10.3109\/00313028909059522_bib0110","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1002\/1097-0142(197810)42:4<2032::AID-CNCR2820420453>3.0.CO;2-O","article-title":"Pathologic findings from the National Surgical Adjuvant Breast Project (Protocol No 4). V. Significance of axillary nodal micro- and macrometastases","volume":"42","author":"Fisher","year":"1978","journal-title":"Cancer"},{"key":"10.3109\/00313028909059522_bib0115","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1002\/1097-0142(196111\/12)14:6<1266::AID-CNCR2820140617>3.0.CO;2-9","article-title":"Significance of occult metastases. A study of breast cancer","volume":"14","author":"Pickren","year":"1961","journal-title":"Cancer"},{"key":"10.3109\/00313028909059522_bib0120","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/00000658-197101000-00006","article-title":"Significance of axillary macrometastases and micrometastases in mammary cancer","volume":"173","author":"Huvos","year":"1971","journal-title":"Ann Surg"},{"key":"10.3109\/00313028909059522_bib0125","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/00000658-198111000-00006","article-title":"Axillary micro- and macrometastases in breast cancer","volume":"194","author":"Rosen","year":"1981","journal-title":"Ann Surg"},{"key":"10.3109\/00313028909059522_bib0130","first-page":"67","article-title":"Occult axillary lymph node metastases in invasive breast carcinoma: Characteristics of the primary tumour and significance of the metastases","volume":"2","author":"Wilkinson","year":"1982","journal-title":"Pathol Ann"},{"key":"10.3109\/00313028909059522_bib0135","doi-asserted-by":"crossref","first-page":"296","DOI":"10.3109\/00313028609059480","article-title":"Antibody probes in the diagnosis of anaplastic tumours. I. Malignant round cell tumours","volume":"18","author":"AS-Y","year":"1986","journal-title":"Pathology"}],"container-title":["Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031302516365175?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031302516365175?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T16:56:18Z","timestamp":1546448178000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031302516365175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1989]]}},"alternative-id":["S0031302516365175"],"URL":"https:\/\/doi.org\/10.3109\/00313028909059522","relation":{},"ISSN":["0031-3025"],"issn-type":[{"value":"0031-3025","type":"print"}],"subject":[],"published":{"date-parts":[[1989]]}}}