{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T09:44:55Z","timestamp":1785750295900,"version":"3.56.0"},"reference-count":46,"publisher":"Informa UK Limited","issue":"10","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Xenobiotica"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.3109\/00498254.2014.903532","type":"journal-article","created":{"date-parts":[[2014,3,21]],"date-time":"2014-03-21T13:37:37Z","timestamp":1395409057000},"page":"893-901","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":31,"title":["Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs"],"prefix":"10.3109","volume":"44","author":[{"given":"Takashi","family":"Koyanagi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Yamaura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Yano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soonih","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2014,3,21]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.106.012088"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.30.10.1059"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1172\/JCI107647","volume":"53","author":"Branch RA","year":"1974","journal-title":"J Clin Invest"},{"key":"CIT0004","first-page":"391","volume":"9","author":"Chang T","year":"1974","journal-title":"Res Commun Chem Pathol Pharmacol"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.2174\/092986710790416326"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1476-5381.1977.tb08423.x","volume":"61","author":"Curry SH","year":"1977","journal-title":"Br J Pharmacol"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1023\/A:1018943613122","volume":"10","author":"Davies B","year":"1993","journal-title":"Pharm Res"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1002\/jps.2600550706","volume":"55","author":"De Silva JA","year":"1966","journal-title":"J Pharm Sci"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1982.tb07093.x"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(68)90187-1"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-135-35157"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1023\/A:1015827908309","volume":"7","author":"Dressman JB","year":"1990","journal-title":"Pharm Res"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0140-6736(87)90167-X","volume":"1","author":"Elseviers MM","year":"1987","journal-title":"Lancet"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9236(96)90001-6"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/22.1.37"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/S0022-3565(25)32906-X","volume":"220","author":"Greenblatt DJ","year":"1982","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1973.tb08339.x"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03550080069041"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1248\/bpb.26.1442","volume":"26","author":"Ikegami K","year":"2003","journal-title":"Biol Pharm Bull"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1080\/03602530902722679"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0022-3565(25)30657-9","volume":"199","author":"Klotz U","year":"1976","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1172\/JCI107938","volume":"55","author":"Klotz U","year":"1975","journal-title":"J Clin Invest"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF00542199","volume":"32","author":"Kumana CR","year":"1987","journal-title":"Eur J Clin Pharmacol"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.31.9.1338"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0014-2999(70)90308-0","volume":"9","author":"Marcucci F","year":"1970","journal-title":"Eur J Pharmacol"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0014-2999(68)90036-8","volume":"4","author":"Marcucci F","year":"1968","journal-title":"Eur J Pharmacol"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glr118"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1124\/pr.56.2.4"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1248\/cpb.38.2224","volume":"38","author":"Mizuta H","year":"1990","journal-title":"Chem Pharm Bull (Tokyo)"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1248\/cpb.38.2810","volume":"38","author":"Mizuta H","year":"1990","journal-title":"Chem Pharm Bull (Tokyo)"},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/BF02280765","volume":"43","author":"Molinaro M","year":"1992","journal-title":"Eur J Clin Pharmacol"},{"key":"CIT0032","first-page":"1185","volume":"32","author":"Okazaki O","year":"1984","journal-title":"Chemotherapy (Tokyo)"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1984.tb02548.x"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1990.tb03691.x"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/BF01959460","volume":"11","author":"Rademaker CM","year":"1989","journal-title":"Pharm Weekbl Sci"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1023\/A:1018970323716","volume":"10","author":"Russell TL","year":"1993","journal-title":"Pharm Res"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0022-3565(25)27131-2","volume":"149","author":"Schwartz MA","year":"1965","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1016\/0006-2952(68)90134-2","volume":"17","author":"Schwartz MA","year":"1968","journal-title":"Biochem Pharmacol"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/0006-2952(89)90314-6","volume":"28","author":"Seddon T","year":"1989","journal-title":"Biochem Pharmacol"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0021-9258(18)56808-3","volume":"179","author":"Soberman R","year":"1949","journal-title":"J Biol Chem"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"789","DOI":"10.3181\/00379727-74-18050","volume":"74","author":"Soberman RJ","year":"1950","journal-title":"Proc Soc Exp Biol Med"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0009-9236(97)90166-1","volume":"61","author":"Sotaniemi EA","year":"1997","journal-title":"Clin Pharmacol Ther"},{"key":"CIT0043","first-page":"1203","volume":"32","author":"Sudo K","year":"1984","journal-title":"Chemotherapy (Tokyo)"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/cpt1975184425","volume":"18","author":"Vestal RE","year":"1975","journal-title":"Clin Pharmacol Ther"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1365-2125.1992.tb04039.x","volume":"33","author":"Viani A","year":"1992","journal-title":"Br J Clin Pharmacol"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0090-9556(25)08738-0","volume":"17","author":"Vickers FF","year":"1989","journal-title":"Drug Metab Dispos"}],"container-title":["Xenobiotica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/00498254.2014.903532","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T03:47:17Z","timestamp":1746157637000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/00498254.2014.903532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,21]]},"references-count":46,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2014,4,29]]},"published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.3109\/00498254.2014.903532"],"URL":"https:\/\/doi.org\/10.3109\/00498254.2014.903532","relation":{},"ISSN":["0049-8254","1366-5928"],"issn-type":[{"value":"0049-8254","type":"print"},{"value":"1366-5928","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,21]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ixen20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ixen20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}