{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:32:39Z","timestamp":1761964359877},"reference-count":110,"publisher":"Informa UK Limited","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Asthma"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.3109\/02770903.2011.648298","type":"journal-article","created":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T15:09:48Z","timestamp":1326208188000},"page":"121-128","source":"Crossref","is-referenced-by-count":25,"title":["Histone Deacetylases and Their Role in Asthma"],"prefix":"10.3109","volume":"49","author":[{"given":"Simon G.","family":"Royce","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom C.","family":"Karagiannis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2012,1,10]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1358\/dot.2009.45.11.1437052"},{"issue":"7","key":"CIT0002","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1517\/13543784.16.7.1111","volume":"16","author":"Duvic M","year":"2007","journal-title":"Expert Opin Investig Drugs"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1586\/era.10.88"},{"issue":"1","key":"CIT0004","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/nbt1272","volume":"25","author":"Marks PA","year":"2007","journal-title":"Nat Biotechnol"},{"issue":"9","key":"CIT0005","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/nrd2133","volume":"5","author":"Bolden JE","year":"2006","journal-title":"Nat Rev Drug Discov"},{"issue":"10","key":"CIT0006","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1158\/1541-7786.MCR-07-0324","volume":"5","author":"Dokmanovic M","year":"2007","journal-title":"Mol Cancer Res"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1038\/nrd772"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagrm.2010.05.008"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2010.510514"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.22185"},{"issue":"2","key":"CIT0011","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/jcb.20532","volume":"96","author":"Dokmanovic M","year":"2005","journal-title":"J Cell Biochem"},{"issue":"4","key":"CIT0012","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1158\/1535-7163.MCT-06-0623","volume":"6","author":"De los Santos M","year":"2007","journal-title":"Mol Cancer Ther"},{"issue":"2","key":"CIT0013","first-page":"166","volume":"3","author":"Kim HJ","year":"2011","journal-title":"Am J Transl Res"},{"issue":"1","key":"CIT0014","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/nrc1779","volume":"6","author":"Minucci S","year":"2006","journal-title":"Nat Rev Cancer"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.4.7.1922"},{"issue":"27","key":"CIT0016","doi-asserted-by":"crossref","first-page":"3963","DOI":"10.1038\/sj.onc.1210174","volume":"26","author":"Karagiannis TC","year":"2007","journal-title":"Oncogene"},{"issue":"4","key":"CIT0017","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1182\/blood-2005-09-008086","volume":"108","author":"Sanchez-Gonzalez B","year":"2006","journal-title":"Blood"},{"issue":"7","key":"CIT0018","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1038\/sj.bjc.6605293","volume":"101","author":"Munster PN","year":"2009","journal-title":"Br J Cancer"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2011.01296.x"},{"issue":"2","key":"CIT0020","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jphotobiol.2011.02.022","volume":"103","author":"Briggs B","year":"2011","journal-title":"J Photochem Photobiol B"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208585"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-2786"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1038\/ncponc0346"},{"issue":"13","key":"CIT0024","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.drudis.2011.05.012","volume":"16","author":"Kwa FA","year":"2011","journal-title":"Drug Discov Today"},{"issue":"2","key":"CIT0025","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0960-894X(00)00605-3","volume":"11","author":"Colletti SL","year":"2001","journal-title":"Bioorg Med Chem Lett"},{"issue":"2","key":"CIT0026","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0960-894X(00)00604-1","volume":"11","author":"Colletti SL","year":"2001","journal-title":"Bioorg Med Chem Lett"},{"issue":"23","key":"CIT0027","doi-asserted-by":"crossref","first-page":"13143","DOI":"10.1073\/pnas.93.23.13143","volume":"93","author":"Darkin-Rattray SJ","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"CIT0028","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1128\/AAC.00757-07","volume":"52","author":"Andrews KT","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"CIT0029","doi-asserted-by":"crossref","first-page":"292","DOI":"10.2174\/156802609788085313","volume":"9","author":"Andrews KT","year":"2009","journal-title":"Curr Top Med Chem"},{"issue":"6","key":"CIT0030","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1172\/JCI19137","volume":"112","author":"Kook H","year":"2003","journal-title":"J Clin Invest"},{"issue":"22","key":"CIT0031","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.1161\/CIRCULATIONAHA.106.625467","volume":"113","author":"Kong Y","year":"2006","journal-title":"Circulation"},{"issue":"1","key":"CIT0032","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1161\/CIRCULATIONAHA.105.559724","volume":"113","author":"Kee HJ","year":"2006","journal-title":"Circulation"},{"issue":"1","key":"CIT0033","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1517\/14740338.7.1.53","volume":"7","author":"Berry JM","year":"2008","journal-title":"Expert Opin Drug Saf"},{"issue":"10","key":"CIT0034","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1096\/fj.08-108548","volume":"22","author":"Granger A","year":"2008","journal-title":"FASEB J"},{"issue":"31","key":"CIT0035","doi-asserted-by":"crossref","first-page":"28930","DOI":"10.1074\/jbc.M303113200","volume":"278","author":"Antos CL","year":"2003","journal-title":"J Biol Chem"},{"issue":"10","key":"CIT0036","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1038\/nrd2681","volume":"7","author":"Kazantsev AG","year":"2008","journal-title":"Nat Rev Drug Discov"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2009.06.002"},{"issue":"23","key":"CIT0038","doi-asserted-by":"crossref","first-page":"6128","DOI":"10.1523\/JNEUROSCI.0296-07.2007","volume":"27","author":"Vecsey CG","year":"2007","journal-title":"J Neurosci"},{"issue":"4","key":"CIT0039","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.cell.2007.02.005","volume":"128","author":"Kouzarides T","year":"2007","journal-title":"Cell"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1073\/pnas.51.5.786","volume":"51","author":"Allfrey VG","year":"1964","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1126\/science.144.3618.559"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagrm.2008.06.005"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev.biochem.70.1.81","volume":"70","author":"Roth SY","year":"2001","journal-title":"Annu Rev Biochem"},{"issue":"37","key":"CIT0044","doi-asserted-by":"crossref","first-page":"5541","DOI":"10.1038\/sj.onc.1210620","volume":"26","author":"Xu WS","year":"2007","journal-title":"Oncogene"},{"issue":"8","key":"CIT0045","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1002\/(SICI)1521-1878(199808)20:8<615::AID-BIES4>3.0.CO;2-H","volume":"20","author":"Kuo MH","year":"1998","journal-title":"Bioessays"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1042\/bj20021321"},{"issue":"26","key":"CIT0048","doi-asserted-by":"crossref","first-page":"14178","DOI":"10.1073\/pnas.250422697","volume":"97","author":"Tanner KG","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"issue":"10","key":"CIT0049","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1089\/ars.2009.3064","volume":"13","author":"Wood LG","year":"2010","journal-title":"Antioxid Redox Signal"},{"issue":"4","key":"CIT0050","doi-asserted-by":"crossref","first-page":"L774","DOI":"10.1152\/ajplung.00110.2004","volume":"287","author":"Donnelly LE","year":"2004","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2009.01.005"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"7134","DOI":"10.3402\/PBA.v1i0.7134","volume":"1","author":"Royce SG","year":"2011","journal-title":"Pathobiol Aging Age-Related Dis"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1038\/35106079"},{"issue":"2","key":"CIT0054","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0959-437X(03)00015-7","volume":"13","author":"Yang XJ","year":"2003","journal-title":"Curr Opin Genet Dev"},{"issue":"37","key":"CIT0055","doi-asserted-by":"crossref","first-page":"5450","DOI":"10.1038\/sj.onc.1210613","volume":"26","author":"Martin M","year":"2007","journal-title":"Oncogene"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2008.08.016"},{"issue":"15","key":"CIT0057","doi-asserted-by":"crossref","first-page":"11219","DOI":"10.1074\/jbc.M109.042754","volume":"285","author":"Gao YS","year":"2010","journal-title":"J Biol Chem"},{"issue":"6887","key":"CIT0058","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1038\/417455a","volume":"417","author":"Hubbert C","year":"2002","journal-title":"Nature"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00939-5"},{"issue":"1","key":"CIT0060","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/ni.1673","volume":"10","author":"Villagra A","year":"2009","journal-title":"Nat Immunol"},{"issue":"2","key":"CIT0061","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/onc.2009.334","volume":"29","author":"Villagra A","year":"2010","journal-title":"Oncogene"},{"issue":"28","key":"CIT0062","doi-asserted-by":"crossref","first-page":"17174","DOI":"10.1016\/S0021-9258(17)44885-X","volume":"265","author":"Yoshida M","year":"1990","journal-title":"J Biol Chem"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.24.6969"},{"issue":"5","key":"CIT0064","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1002\/med.10017","volume":"22","author":"Blaheta RA","year":"2002","journal-title":"Med Res Rev"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-0186(00)00013-9"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-007-7079-x"},{"issue":"1","key":"CIT0067","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1365-2222.2004.02006.x","volume":"35","author":"Choi JH","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200305-659OC"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2110060"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2007.07.016"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1177\/1753465809348648"},{"issue":"3","key":"CIT0072","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.jaci.2007.12.1156","volume":"121","author":"Bhavsar P","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00117504"},{"issue":"2","key":"CIT0074","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.pharmthera.2007.06.009","volume":"116","author":"Ito K","year":"2007","journal-title":"Pharmacol Ther"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1080\/15412550500346683"},{"issue":"8","key":"CIT0076","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1096\/fj.04-2303fje","volume":"19","author":"Waltregny D","year":"2005","journal-title":"FASEB J"},{"issue":"5","key":"CIT0077","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1093\/emboj\/cdg115","volume":"22","author":"Zhang Y","year":"2003","journal-title":"EMBO J"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041892"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2010.01199.x"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60326-3"},{"issue":"3","key":"CIT0081","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/nri2254","volume":"8","author":"Barnes PJ","year":"2008","journal-title":"Nat Rev Immunol"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0706736"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200512-1930OC"},{"issue":"3","key":"CIT0084","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1183\/09031936.94.07030579","volume":"7","author":"Barnes PJ","year":"1994","journal-title":"Eur Respir J"},{"issue":"4","key":"CIT0085","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1183\/09031936.95.08040637","volume":"8","author":"Rabe KF","year":"1995","journal-title":"Eur Respir J"},{"issue":"2","key":"CIT0086","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1164\/ajrccm.164.2.2006043","volume":"164","author":"Lim S","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"CIT0087","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1164\/ajrccm\/147.3.518","volume":"147","author":"Ward AJ","year":"1993","journal-title":"Am Rev Respir Dis"},{"issue":"3","key":"CIT0088","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1183\/09031936.96.09030456","volume":"9","author":"Jaffar ZH","year":"1996","journal-title":"Eur Respir J"},{"issue":"8904","key":"CIT0089","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/S0140-6736(94)90127-9","volume":"343","author":"Sullivan P","year":"1994","journal-title":"Lancet"},{"issue":"8","key":"CIT0090","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1183\/09031936.96.09081672","volume":"9","author":"Finnerty JP","year":"1996","journal-title":"Eur Respir J"},{"issue":"2","key":"CIT0091","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1365-2222.1988.tb02853.x","volume":"18","author":"Brenner M","year":"1988","journal-title":"Clin Allergy"},{"issue":"6","key":"CIT0092","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1164\/ajrccm.151.6.7767539","volume":"151","author":"Kidney J","year":"1995","journal-title":"Demonstration by withdrawal of therapy. Am J Respir Crit Care Med"},{"issue":"6","key":"CIT0093","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.2165\/00003495-199856060-00018","volume":"56","author":"Markham A","year":"1998","journal-title":"Drugs"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199711133372002"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10122754"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.132556899"},{"key":"CIT0098","first-page":"385","volume":"3","author":"Burton B","year":"1882","journal-title":"Am Chem J"},{"key":"CIT0099","first-page":"457","volume":"19","author":"Lebreton S","year":"1964","journal-title":"Therapie"},{"key":"CIT0100","first-page":"451","volume":"19","author":"Lebreton S","year":"1964","journal-title":"Therapie"},{"key":"CIT0101","first-page":"435","volume":"18","author":"Meunier H","year":"1963","journal-title":"Therapie"},{"issue":"20","key":"CIT0102","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1001\/jama.1978.03290200068031","volume":"240","author":"Lewis JR","year":"1978","journal-title":"J Am Med Assoc"},{"issue":"3","key":"CIT0103","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1528-1157.1965.tb03789.x","volume":"6","author":"Stevens H","year":"1965","journal-title":"Epilepsia"},{"issue":"7550","key":"CIT0104","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/S0140-6736(68)91150-1","volume":"1","author":"Sayar B","year":"1968","journal-title":"Lancet"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M101287200"},{"issue":"13","key":"CIT0106","doi-asserted-by":"crossref","first-page":"3411","DOI":"10.1093\/emboj\/cdg315","volume":"22","author":"Kramer OH","year":"2003","journal-title":"EMBO J"},{"issue":"6","key":"CIT0107","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.pupt.2009.08.005","volume":"22","author":"Dombrowsky H","year":"2009","journal-title":"Pulm Pharmacol Ther"},{"issue":"13","key":"CIT0108","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1016\/j.intimp.2008.08.017","volume":"8","author":"Assem ESK","year":"2008","journal-title":"Int Immunopharmacol"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0430973100"},{"issue":"46","key":"CIT0110","doi-asserted-by":"crossref","first-page":"20003","DOI":"10.1073\/pnas.1013754107","volume":"107","author":"Namdar M","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"28","key":"CIT0111","doi-asserted-by":"crossref","first-page":"9633","DOI":"10.1073\/pnas.0803749105","volume":"105","author":"Parmigiani RB","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"issue":"9","key":"CIT0112","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1016\/j.bmcl.2011.01.134","volume":"21","author":"Tang W","year":"2011","journal-title":"Bioorg Med Chem Lett"}],"container-title":["Journal of Asthma"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10256018808623883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T12:08:19Z","timestamp":1686658099000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/02770903.2011.648298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,10]]},"references-count":110,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2012,1,25]]},"published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.3109\/02770903.2011.648298"],"URL":"https:\/\/doi.org\/10.3109\/02770903.2011.648298","relation":{},"ISSN":["0277-0903","1532-4303"],"issn-type":[{"value":"0277-0903","type":"print"},{"value":"1532-4303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,10]]}}}