{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:55:58Z","timestamp":1791366958723,"version":"4.3.1"},"reference-count":64,"publisher":"MJS Publishing, Medical Journals Sweden AB","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Oncologica"],"published-print":{"date-parts":[[1993,1]]},"DOI":"10.3109\/02841869309083904","type":"journal-article","created":{"date-parts":[[2007,11,21]],"date-time":"2007-11-21T20:02:02Z","timestamp":1195675322000},"page":"149-154","source":"Crossref","is-referenced-by-count":8,"title":["Islet Amyloid Polypeptide\u2014Hen or EGG in Type 2 Diabetes Pathogenesis?"],"prefix":"10.2340","volume":"32","author":[{"given":"Christer","family":"Betsholtz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Christmanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Gebre-Medhin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Westermark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2009,7,8]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1517\/03009734000000014","volume":"77","author":"Westermark P","year":"1972","journal-title":"Upsala J Med Sci"},{"key":"CIT0002","first-page":"291","volume":"81","author":"Westermark P","year":"1973","journal-title":"Acta Pathol Microbiol Scand A"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/0014-4827(89)90407-2","volume":"183","author":"Betsholtz C","year":"1989","journal-title":"Exp Cell Res"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/BF00401195","volume":"35","author":"Westermark P","year":"1992","journal-title":"Diabetologia"},{"key":"CIT0005","first-page":"203","volume":"2","author":"Bretherton-Watt D","year":"1991","journal-title":"TEM"},{"key":"CIT0006","first-page":"295","volume":"15","author":"Leighton B","year":"1990","journal-title":"TIBS"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"17243","DOI":"10.1016\/S0021-9258(19)77825-9","volume":"263","author":"Sanke T","year":"1988","journal-title":"J Biol Chem"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/0014-5793(89)81260-8","volume":"247","author":"Mosselman S","year":"1989","journal-title":"FEBS Lett"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0014-5793(89)81467-X","volume":"251","author":"Betsholtz C","year":"1989","journal-title":"FEBS Lett"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.15.5738"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"118","DOI":"10.2337\/diacare.39.1.118","volume":"39","author":"Betsholtz C","year":"1990","journal-title":"Diabetes"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.1073\/pnas.87.13.5036","volume":"87","author":"Westermark P","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/0006-291X(90)90359-U","volume":"169","author":"Jordan K","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1007\/BF00400208","volume":"33","author":"Nishi M","year":"1990","journal-title":"Diabetologia"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"8628","DOI":"10.1073\/pnas.84.11.3881","volume":"84","author":"Westermark P","year":"1987","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"8628","DOI":"10.1073\/pnas.84.23.8628","volume":"84","author":"Cooper G JS","year":"1987","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"2778","DOI":"10.1210\/endo.130.5.1572293","volume":"130","author":"Braas K M","year":"1992","journal-title":"Endocrinology"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1210\/mend-3-11-1775","volume":"3","author":"Nishi M","year":"1989","journal-title":"Mol Endocrinol"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/0014-5793(90)80314-9","volume":"267","author":"Christmanson L","year":"1990","journal-title":"FEBS Lett"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0167-4781(90)90210-S","volume":"1087","author":"Van Mansfeld A DM","year":"1990","journal-title":"Biochim Biophys Acta"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0014-5793(88)80922-0","volume":"239","author":"Mosselman S","year":"1988","journal-title":"FEBS Lett"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1210\/mend-5-1-143","volume":"5","author":"Madsen O","year":"1991","journal-title":"Mol Endocrinol"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1677\/jme.0.003R001","volume":"3","author":"Ferrier G JM","year":"1989","journal-title":"J Mol Endocrinol"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/0006-291X(89)91732-4","volume":"164","author":"Nakasato M","year":"1989","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/0006-291X(90)90400-H","volume":"169","author":"Asai J","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/BF00305236","volume":"262","author":"Toshimori H","year":"1990","journal-title":"Cell Tissue Res"},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/BF00285291","volume":"32","author":"Lukinius A","year":"1989","journal-title":"Diabetologia"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0014-5793(89)81527-3","volume":"259","author":"Kanatsuka A","year":"1989","journal-title":"FEBS Lett"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/0006-291X(90)90389-5","volume":"169","author":"Nakazato M","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/BF00404025","volume":"34","author":"Hartter E","year":"1991","journal-title":"Diabetologia"},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF00500385","volume":"34","author":"Sanker T","year":"1991","journal-title":"Diabetologia"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"639","DOI":"10.2337\/diab.39.5.639","volume":"39","author":"Mitsukawa T","year":"1990","journal-title":"Diabetes"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0014-5793(90)80210-A","volume":"262","author":"Fehmann H C","year":"1990","journal-title":"FEBS Lett"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0168-8227(90)90043-S","volume":"10","author":"Inoue K","year":"1990","journal-title":"Diabetes Res Clin Pract"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"634","DOI":"10.2337\/diab.39.5.634","volume":"39","author":"Kahn S E","year":"1990","journal-title":"Diabetes"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"752","DOI":"10.2337\/diab.39.6.752","volume":"39","author":"Butler P C","year":"1990","journal-title":"Diabetes"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/0140-6736(90)90197-D","volume":"1","author":"van Jaarsveld B C","year":"1990","journal-title":"Lancet"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/0024-3205(91)90546-N","volume":"48","author":"Gill A M","year":"1991","journal-title":"Life Sci"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1677\/joe.0.1260425","volume":"126","author":"Jamal H","year":"1990","journal-title":"J Endocrinol"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1210\/endo-128-6-2739","volume":"128","author":"Tokuyama Y","year":"1991","journal-title":"Endocrinology"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.2337\/diab.40.12.1701","volume":"40","author":"O'Brien T D","year":"1991","journal-title":"Diabetes"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/BF00297454","volume":"32","author":"Bretherton-Watt D","year":"1989","journal-title":"Diabetologia"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1172\/JCI114528","volume":"85","author":"Ogawa A","year":"1990","journal-title":"J Clin Invest"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/0006-291X(89)92529-1","volume":"160","author":"Ohsawa H","year":"1989","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0167-0115(90)90192-Y","volume":"31","author":"Silvestre R A","year":"1990","journal-title":"Regul Pept"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/0006-291X(90)90524-Q","volume":"170","author":"O'Brien T D","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0047","doi-asserted-by":"crossref","first-page":"871","DOI":"10.2337\/diab.39.7.871","volume":"39","author":"Nagamatsu S","year":"1990","journal-title":"Diabetes"},{"key":"CIT0048","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/0006-291X(90)90636-2","volume":"167","author":"Fehmann H-C","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0049","doi-asserted-by":"crossref","first-page":"R9","DOI":"10.1677\/joe.0.124R009","volume":"124","author":"Ghatei M A","year":"1990","journal-title":"J Endocrinol"},{"key":"CIT0050","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0167-0115(88)90419-3","volume":"23","author":"Pettersson M","year":"1988","journal-title":"Regul Pept"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"875","DOI":"10.2337\/diabetes.39.7.875","volume":"39","author":"Morishita T","year":"1990","journal-title":"Diabetes"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/335632a0","volume":"335","author":"Leighton B","year":"1988","journal-title":"Nature"},{"key":"CIT0053","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/0006-291X(90)92053-3","volume":"167","author":"Johnson K H","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1007\/BF00401051"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"568","DOI":"10.2337\/diab.40.5.568","volume":"40","author":"Frontoni S","year":"1991","journal-title":"Diabetes"},{"key":"CIT0056","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1042\/bj2690019","volume":"269","author":"Leighton B","year":"1990","journal-title":"Biochem J"},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/BF00400848","volume":"35","author":"Zierath J","year":"1992","journal-title":"Diabetologia"},{"key":"CIT0058","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/0006-291X(91)91476-S","volume":"174","author":"Deems R O","year":"1991","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(91)80380-L"},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/0006-291X(89)92391-7","volume":"162","author":"Datta H K","year":"1989","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/0196-9781(91)90148-I"},{"key":"CIT0062","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/0196-9781(91)90038-Q","volume":"12","author":"Balasubramaniam A","year":"1991","journal-title":"Peptides"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(91)91644-G"},{"key":"CIT0064","doi-asserted-by":"crossref","first-page":"395","DOI":"10.2337\/diab.40.3.395","volume":"40","author":"Stephens T W","year":"1991","journal-title":"Diabetes"}],"container-title":["Acta Oncologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/02841869309083904","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:38:03Z","timestamp":1791365883000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicaljournalssweden.se\/actaoncologica\/article\/view\/28525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1]]},"references-count":64,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2009,7,8]]},"published-print":{"date-parts":[[1993,1]]}},"alternative-id":["10.3109\/02841869309083904"],"URL":"https:\/\/doi.org\/10.3109\/02841869309083904","relation":{},"ISSN":["0284-186X","1651-226X"],"issn-type":[{"value":"0284-186X","type":"print"},{"value":"1651-226X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,1]]}}}