{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T19:26:56Z","timestamp":1782329216765,"version":"3.54.5"},"reference-count":71,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug Metabolism Reviews"],"published-print":{"date-parts":[[1984,1]]},"DOI":"10.3109\/03602538409029973","type":"journal-article","created":{"date-parts":[[2007,11,16]],"date-time":"2007-11-16T14:22:43Z","timestamp":1195222963000},"page":"557-589","source":"Crossref","is-referenced-by-count":79,"title":["Design and Structure-Activity Relationships of Antidotes to Organophosphorus Anticholinesterase Agents"],"prefix":"10.1080","volume":"15","author":[{"given":"Allan P.","family":"Gray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2008,9,22]]},"reference":[{"key":"CIT0001","volume-title":"Medical Protection against Chemical-Warfare Agents","author":"Stockholm International Peace Research Institute","year":"1976"},{"key":"CIT0002","unstructured":"Koelle G. B. The Pharmacological Basis of Therapeutics, 4th ed., L. S. Goodman, A. Gilman. Macmillan Co., New York 1970; 442\u2013465"},{"key":"CIT0003","unstructured":"NATO Handbook on the Medical Aspects of NBC Defensive Operations. Department of the Air Force AFP161\u20133. 1973, AMedP-6, TS 17682 505\u2013733; Department of the Army FM 8\u20139; Department of the Navy NAVMEDP-5059;"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(80)90617-7"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(82)90466-0"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pa.21.040181.002455"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1042\/bj1850739"},{"key":"CIT0009","unstructured":"Cadigan F. C., Chipman M. 5\u20137, in Ref. 4"},{"key":"CIT0010","unstructured":"Main A. R. Biology of Cholinergic Function, A. M. Goldberg, I. Hanin. Raven Press, New York 1976; 269\u2013353"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-7130-2"},{"key":"CIT0012","first-page":"267","volume":"24","author":"Cavallito C. J","year":"1980","journal-title":"Progr. Drug Res."},{"key":"CIT0013","first-page":"225","volume":"47","author":"Aldridge W. N","year":"1975","journal-title":"Croat. Chem. Act."},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/0968-0004(80)90014-6"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(67)90006-9"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.3109\/01480547809016047"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(78)90615-X"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1983.tb13573.x"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.3109\/01480548009002226"},{"key":"CIT0021","first-page":"69","volume":"227","author":"Wicker L.","year":"1977","journal-title":"Arch. Int. Pharmacodyn. Ther."},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(55)90040-8"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(56)90418-0"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(56)90288-0"},{"key":"CIT0025","first-page":"752","volume":"18","author":"Wilson I. B","year":"1959","journal-title":"Fed. Proc."},{"key":"CIT0026","first-page":"1","volume":"14","author":"Luttringhaus A.","year":"1964","journal-title":"Arzneim.-Forsch."},{"key":"CIT0027","first-page":"5","volume":"14","author":"Erdmann W. D.","year":"1964","journal-title":"Arzneim.-Forsch."},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(80)90432-4"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(59)90321-X"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(65)90082-1"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1126\/science.1166305"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1021\/jm00223a017"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1021\/jm00223a018"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1021\/jm00223a019"},{"key":"CIT0036","first-page":"321","volume":"232","author":"Rump S.","year":"1978","journal-title":"Arch. Int. Pharmacodyn."},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(80)90216-1"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1021\/jo01264a067"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1021\/jm00297a024"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(81)90252-5"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2744(78)90243-7"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(76)90049-6"},{"key":"CIT0044","first-page":"85","volume":"7","author":"Schoene K","year":"1980","journal-title":"Monogr. Neural Sci."},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1021\/jm00356a006"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(77)90354-9"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1021\/jm00301a034"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1021\/jm00284a011"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-7158.1971.tb09935.x"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3908(73)90005-1"},{"key":"CIT0051","first-page":"449","author":"Eckernas S. -A","year":"1977","journal-title":"Acta Physiol. Scand."},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.3891\/acta.chem.scand.20-1240"},{"key":"CIT0055","first-page":"607","volume":"37","author":"Mager P. P.","year":"1982","journal-title":"Pharmazi."},{"key":"CIT0056","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0021-9258(18)56051-8","volume":"190","author":"Wilson I. B","year":"1951","journal-title":"J. Biol. Chem."},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0021-9258(18)44817-X","volume":"199","author":"Wilson I. B","year":"1952","journal-title":"J. Biol. Chem."},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1039\/df9552000119"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(55)90075-8"},{"key":"CIT0060","first-page":"462","volume":"10","author":"Childs A. F.","year":"1955","journal-title":"Br. J. Pharmacol."},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.3891\/acta.chem.scand.20-1240"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1038\/1821498a0"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(58)90077-8"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1002\/anie.197203071"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-7158.1967.tb09554.x"},{"key":"CIT0067","first-page":"55","volume":"20","author":"Dirks E.","year":"1970","journal-title":"Arzneim.-Forsch."},{"key":"CIT0068","first-page":"197","volume":"20","author":"Dirks E.","year":"1970","journal-title":"Arzneim.-Forsch."},{"key":"CIT0069","first-page":"450","volume":"36","author":"Mager P. P","year":"1981","journal-title":"Pharmazi."},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-060307-7.50010-9"},{"key":"CIT0071","first-page":"800","volume":"37","author":"Mager P. P","year":"1982","journal-title":"Pharmazi."},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1021\/jm00197a006"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1021\/jm00300a043"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.19753080106"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600610433"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1021\/jm00242a017"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1021\/jm00142a003"},{"key":"CIT0078","first-page":"159","volume":"31","author":"Maksimovic M.","year":"1981","journal-title":"Acta Pharm. Jugosl."}],"container-title":["Drug Metabolism Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/03602538409029973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T00:54:32Z","timestamp":1630112072000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/03602538409029973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,1]]},"references-count":71,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2008,9,22]]},"published-print":{"date-parts":[[1984,1]]}},"alternative-id":["10.3109\/03602538409029973"],"URL":"https:\/\/doi.org\/10.3109\/03602538409029973","relation":{},"ISSN":["0360-2532","1097-9883"],"issn-type":[{"value":"0360-2532","type":"print"},{"value":"1097-9883","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,1]]}}}