{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T10:16:32Z","timestamp":1768558592505,"version":"3.49.0"},"reference-count":70,"publisher":"Informa UK Limited","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2000,1]]},"DOI":"10.3109\/07853890009002025","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T08:34:46Z","timestamp":1260261286000},"page":"493-500","source":"Crossref","is-referenced-by-count":33,"title":["Human prion diseases"],"prefix":"10.1080","volume":"32","author":[{"given":"Matti","family":"Haltia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,8]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/214764a0","volume":"214","author":"Alper T","year":"1967","journal-title":"Nature"},{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/2151043a0","volume":"215","author":"Griffiths JS","year":"1967","journal-title":"Nature"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1126\/science.6801762","volume":"216","author":"Prusiner SB","year":"1982","journal-title":"Science"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S0968-0004(96)10063-3","volume":"21","author":"Prusiner SB","year":"1996","journal-title":"Trends Biol Sci"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1126\/science.279.5347.42","volume":"279","author":"Chesebro","year":"1998","journal-title":"Science"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"73546","DOI":"10.1016\/0092-8674(85)90333-2","volume":"40","author":"Oesch B","year":"1985","journal-title":"Cell"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0092-8674(87)90150-4","volume":"51","author":"Stahl N","year":"1987","journal-title":"Cell"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S0014-5793(97)00920-4","volume":"413","author":"Riek R","year":"1997","journal-title":"FEBS Lett"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"10086","DOI":"10.1073\/pnas.94.19.10086","volume":"94","author":"James T L","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/356577a0","volume":"356","author":"Bueler H","year":"1992","journal-title":"Nature"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/380639a0","volume":"380","author":"Tobler I","year":"1996","journal-title":"Nature"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/37733","volume":"390","author":"Brown D R","year":"1997","journal-title":"Nature"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1006\/exnr.1997.6505","volume":"146","author":"Brown D R","year":"1997","journal-title":"Exp Neurol"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1038\/380528a0","volume":"380","author":"Sakaguchi S","year":"1996","journal-title":"Nature"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"133947","DOI":"10.1016\/0092-8674(93)90360-3","volume":"73","author":"Bueler H","year":"1993","journal-title":"Cell"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"10608","DOI":"10.1073\/pnas.90.22.10608","volume":"90","author":"Prusiner S B","year":"1993","journal-title":"Proc Nutl Acad Sci USA"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"10962","DOI":"10.1073\/pnas.90.23.10962","volume":"90","author":"Pan K","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"11030","DOI":"10.1073\/pnas.95.19.11030","volume":"95","author":"Westaway D","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"19173","DOI":"10.1074\/jbc.270.32.19173","volume":"270","author":"Chen S G","year":"1995","journal-title":"J Biol Chem"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"12661","DOI":"10.1074\/jbc.271.21.12661","volume":"271","author":"Petersen R B","year":"1996","journal-title":"J Biol Chem"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/ana.410390613","volume":"39","author":"Parchi P","year":"1996","journal-title":"Ann Neurol"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1046\/j.1365-2990.2000.00253.x","volume":"26","author":"Telling GC","year":"2000","journal-title":"Neuropathol Appl Neurobiol"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1128\/JVI.66.4.2096-2101.1992","volume":"66","author":"Bessen R A","year":"1992","journal-title":"J Virol"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1126\/science.1675487","volume":"252","author":"Prusiner SB","year":"1991","journal-title":"Science"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1073\/pnas.91.7.2839","volume":"91","author":"Monari L","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1126\/science.274.5295.2079","volume":"274","author":"Telling G C","year":"1996","journal-title":"Science"},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"903244","DOI":"10.1128\/JVI.71.12.9032-9044.1997","volume":"71","author":"Scott M R","year":"1997","journal-title":"J Virol"},{"key":"CIT0028","first-page":"372","volume":"13","author":"Jakob A","year":"1921","journal-title":"Med Klin"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02866081","volume":"57","author":"Creutzfeldt HG","year":"1920","journal-title":"Z Gesamte Neurol Psychiatr"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1056\/NEJM195711142572005","volume":"257","author":"Gajdusek D C","year":"1957","journal-title":"N Engl J Med"},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0140-6736(59)92081-1","volume":"11","author":"Hadlow WJ","year":"1959","journal-title":"Lancet"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/209794a0","volume":"209","author":"Gajdusek D C","year":"1966","journal-title":"Nature"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1126\/science.161.3839.388","volume":"161","author":"Gibbs CJ","year":"1968","journal-title":"Science"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/BF02877841","volume":"92","author":"Kirschbaum WR","year":"1924","journal-title":"Z Neurol Psychiatr"},{"key":"CIT0035","first-page":"906","volume":"78","author":"Gerstmann J","year":"1928","journal-title":"Wien Med Wochenschr"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1007\/BF02865827","volume":"154","author":"Gerstmann J","year":"1936","journal-title":"Z Neurol Psychiatr"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/brain\/96.1.1","volume":"96","author":"Roos R","year":"1973","journal-title":"Brain"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1093\/brain\/104.3.559","volume":"104","author":"Masters C L","year":"1981","journal-title":"Bruin"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1056\/NEJM199202133260704","volume":"326","author":"Medori R","year":"1992","journal-title":"N Engl J Med"},{"key":"CIT0040","first-page":"465","volume-title":"Prion biology and diseases","author":"Will R G","year":"1999"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0022-510X(81)90015-0","volume":"52","author":"Monreal J","year":"1981","journal-title":"J Neurol Sci"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/BF00162311","volume":"1","author":"Brown P","year":"1985","journal-title":"Eur J Epidemiol"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1056\/NEJM199812313392707","volume":"339","author":"Johnson R T","year":"1998","journal-title":"N Engl J Med"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1001\/archneur.1996.00550020074017","volume":"53","author":"Steinhoff B J","year":"1996","journal-title":"Arch Neurol"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1148\/radiology.199.3.8638007","volume":"199","author":"Finkenstaedt M","year":"1996","journal-title":"Radiology"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1056\/NEJM199609263351303","volume":"335","author":"Hsich G","year":"1996","journal-title":"N Engl J Med"},{"key":"CIT0047","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/ana.410360307","volume":"36","author":"Haltia M","year":"1994","journal-title":"Ann Neurol"},{"key":"CIT0048","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1750-3639.1995.tb00625.x","volume":"5","author":"Budka H","year":"1995","journal-title":"Brain Pathol"},{"key":"CIT0049","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/brain\/101.2.333","volume":"101","author":"Masters C L","year":"1978","journal-title":"Brain"},{"key":"CIT0050","first-page":"1411","volume":"140","author":"Muramoto T","year":"1992","journal-title":"Am J Pathol"},{"key":"CIT0051","first-page":"692","volume":"290","author":"Duffy P","year":"1974","journal-title":"N Engl J Med"},{"key":"CIT0052","first-page":"466","volume":"8","author":"Uchiyama K","year":"1994","journal-title":"Dementia"},{"key":"CIT0053","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1136\/jnnp.63.3.388","volume":"63","author":"Heckmann J G","year":"1997","journal-title":"J Neurol Neurosurg Psychiatr"},{"key":"CIT0054","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/S0140-6736(77)91958-4","author":"Bernoulli C","year":"1977","journal-title":"Lancet"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1056\/NEJM198509193131206","volume":"313","author":"Koch T K","year":"1985","journal-title":"N Engl J Med"},{"key":"CIT0056","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/ana.410430611","volume":"43","author":"Will R G","year":"1998","journal-title":"Ann Neurol"},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0022-510X(79)90171-0","volume":"42","author":"Haltia M","year":"1979","journal-title":"J Neurol Sci"},{"key":"CIT0058","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0140-6736(91)91198-4","volume":"337","author":"Goldfarb L G","year":"1991","journal-title":"Lancet"},{"key":"CIT0059","first-page":"509","volume-title":"Prion biology and diseases","author":"Gambetti P","year":"1999"},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/338342a0","volume":"338","author":"Hsiao K","year":"1989","journal-title":"Nature"},{"key":"CIT0061","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0140-6736(89)91713-3","author":"Owen F","year":"1989","journal-title":"Lancet"},{"key":"CIT0062","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/352340a0","volume":"352","author":"Palmer M S","year":"1991","journal-title":"Nature"},{"key":"CIT0063","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0140-6736(96)91412-9","volume":"347","author":"Will R G","year":"1996","journal-title":"Lancet"},{"key":"CIT0064","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/383685a0","volume":"383","author":"Collinge J","year":"1996","journal-title":"Nature"},{"key":"CIT0065","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/381743a0","volume":"381","author":"Lasmkzas C I","year":"1996","journal-title":"Nature"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/39057","volume":"389","author":"Bruce M E","year":"1997","journal-title":"Nature"},{"key":"CIT0067","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/38925","volume":"389","author":"Hill A F","year":"1997","journal-title":"Nature"},{"key":"CIT0068","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0140-6736(00)02559-9","volume":"356","author":"Andrews N J","year":"2000","journal-title":"Lancet"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S0140-6736(99)11419-3","volume":"355","author":"Soto C","year":"2000","journal-title":"Lancet"},{"key":"CIT0070","first-page":"229","volume-title":"Prion biology and diseases","author":"Wickner R B","year":"1999"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/07853890009002025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,24]],"date-time":"2020-05-24T03:55:40Z","timestamp":1590292540000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/07853890009002025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":70,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2009,7,8]]},"published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.3109\/07853890009002025"],"URL":"https:\/\/doi.org\/10.3109\/07853890009002025","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}