{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T06:10:15Z","timestamp":1770617415282,"version":"3.49.0"},"reference-count":260,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Critical Reviews in Biochemistry"],"published-print":{"date-parts":[[1986,1]]},"DOI":"10.3109\/10409238609084657","type":"journal-article","created":{"date-parts":[[2007,11,22]],"date-time":"2007-11-22T05:05:24Z","timestamp":1195707924000},"page":"247-305","source":"Crossref","is-referenced-by-count":162,"title":["Genes for Cytochrome P-450 and Their Regulatio"],"prefix":"10.1080","volume":"19","author":[{"given":"Milton","family":"Adesnik","sequence":"first","affiliation":[{"name":"Department of Cell Biology, New York University School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Atchison","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, New York University School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel W.","family":"Nebert","sequence":"additional","affiliation":[{"name":"Laboratory of Developmental Pharmacology National Instituter of Health, Bethesda, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2008,9,26]]},"reference":[{"issue":"10","key":"e_1_2_1_2_1","first-page":"340","article-title":"Mechanism of induction of cytochrome P-450 by phenobarbita","volume":"256","author":"Adesnik M.","year":"1981","unstructured":"Adesnik M., Bar-Nun S., Maschio F., Zunich M., Lippman A., Bard E. Mechanism of induction of cytochrome P-450 by phenobarbita. J. Biol. Chem. 1981; 256(10)340","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_3_1","volume-title":"Cytochrome P-450 Biochemistry, Biophysics and Environmental Implications","author":"Adesnik M.","year":"1982","unstructured":"Adesnik M., Rivkin E., Kumar A., Lippman A., Raphael C., Atchison M. Genes for cytochrome P-450 and their regulatio. Cytochrome P-450 Biochemistry, Biophysics and Environmental Implications, Y. E. Hietanen, M. Laitinen, O. Hanninen. Elsevier, Amsterdam 1982; 143"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(84)91353-6"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"6777","DOI":"10.1016\/S0021-9258(18)32289-0","article-title":"25-Hydroxylation of C29-steroids and vitamin D3 by a constitutive cytochrome P-450 from rat liver microsome","volume":"258","author":"Andersson S.","year":"1983","unstructured":"Andersson S., Holmberg I., Wikval K. 25-Hydroxylation of C29-steroids and vitamin D3 by a constitutive cytochrome P-450 from rat liver microsome. J. Biol. Chem. 1983; 258: 6777","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_6_1","volume-title":"Evolution of Genes and Proteins","author":"Arnheim N","year":"1983","unstructured":"Arnheim N. Concerted evolution of multigene familie. Evolution of Genes and Proteins, M. Nei, R. K. Koehn. Sinauer Associates, Sunderland, Mass 1983; 38"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.12.7323"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)44416-4"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)40218-3"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(81)90082-9"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90015-6"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)69299-9"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)68292-X"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(78)80250-6"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(79)90400-4"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0026-895X(25)14267-3","article-title":"Substrate specificity of the form of cytochrome P-450 catalyzing the 4-hydroxylation of debrisoquine in ma","volume":"23","author":"Boobis A. R.","year":"1983","unstructured":"Boobis A. R., Murray S., Kahn G. C., Robertz G.-M., Davies D. S. Substrate specificity of the form of cytochrome P-450 catalyzing the 4-hydroxylation of debrisoquine in ma. Mol. Pharmacol. 1983; 23: 474","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)50461-0"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00535a007"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/269713a0"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(78)90078-8"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.50.070181.002025"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.7.4083"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1982.tb07055.x"},{"key":"e_1_2_1_24_1","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/S0026-895X(25)14940-7","article-title":"Neonatal imprinting and hepatic cytochrome P-450. Immunochemical evidence for the presence of a sex-dependent and neonatally imprinted form(s) of heptic cytochrome P-45","volume":"21","author":"Chao H.","year":"1982","unstructured":"Chao H., Chung L. W. K. Neonatal imprinting and hepatic cytochrome P-450. Immunochemical evidence for the presence of a sex-dependent and neonatally imprinted form(s) of heptic cytochrome P-45. Mol. Pharmacol. 1982; 21: 744","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.1.1982.1.231"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)34933-0"},{"key":"e_1_2_1_27_1","first-page":"27","article-title":"Regulation of hepatic drug and steroid metabolism by androgens and estrogen","volume":"4","author":"Colby H. D","year":"1980","unstructured":"Colby H. D. Regulation of hepatic drug and steroid metabolism by androgens and estrogen. Adv. Sex. Horm. Res. 1980; 4: 27","journal-title":"Adv. Sex. Horm. Res."},{"key":"e_1_2_1_28_1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0031-6997(25)07146-7","article-title":"Pharmacological implications of microsomal enzyme inductio","volume":"19","author":"Conney A. H","year":"1967","unstructured":"Conney A. H. Pharmacological implications of microsomal enzyme inductio. Pharm. Rev. 1967; 19: 317","journal-title":"Pharm. Rev."},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1965.tb12248.x"},{"key":"e_1_2_1_30_1","first-page":"4875","article-title":"Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbon","volume":"42","author":"Conney A. H","year":"1982","unstructured":"Conney A. H. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbon. G.H.A. Clowes Memorial Lecture, Cancer Res. 1982; 42: 4875","journal-title":"G.H.A. Clowes Memorial Lecture, Cancer Res."},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(79)90224-7"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)33190-9"},{"key":"e_1_2_1_33_1","first-page":"1812","article-title":"Sex dependence and developmental regulation of cytochrome P-450 isozyme","volume":"43","author":"Dannan G. A.","year":"1984","unstructured":"Dannan G. A., Waxman D. J., Guengerich F. P. Sex dependence and developmental regulation of cytochrome P-450 isozyme. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1984; 43: 1812","journal-title":"Fed. Proc. Fed. Am. Soc. Exp. Biol."},{"key":"e_1_2_1_34_1","first-page":"9","article-title":"Atlas of Protein Sequence and Structur","volume":"5","author":"Dayhoff M. O","year":"1976","unstructured":"Dayhoff M. O. Atlas of Protein Sequence and Structur. Natl. Biomed. Res. Foun. 1976; Vol. 5: 9, Suppl. 2","journal-title":"Natl. Biomed. Res. Foun."},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-94-6-1577"},{"key":"e_1_2_1_36_1","unstructured":"Denison M. S. Harper P. A. Okey A. B. Ah receptor for 2 3 7 8-tetrachlorodibenzo-p-dioxin: co distribution of unoccupied receptor with cytosolic marker enzymes during fractionation of mouse liver rat liver and cultured Hepa-1C1 cell submitted for publication."},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(81)90436-0"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)34071-7"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.52.070183.000521"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(79)91602-4"},{"key":"e_1_2_1_41_1","doi-asserted-by":"crossref","first-page":"7000","DOI":"10.1016\/S0021-9258(19)69090-3","article-title":"Induction and synthesis of cholesterol side chain cleavage cytochrome P-450 by adrenocorticotropin in cultured bovine adrenocortical cell","volume":"256","author":"Du Bois R. N.","year":"1981","unstructured":"Du Bois R. N., Simpson E. R., Kramer R. E., Waterman M. R. Induction and synthesis of cholesterol side chain cleavage cytochrome P-450 by adrenocorticotropin in cultured bovine adrenocortical cell. J. Biol. Chem. 1981; 256: 7000","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)90362-2"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.3109\/00498258209038948"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(80)90617-0"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-105-2-555"},{"key":"e_1_2_1_46_1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/B978-0-12-452810-9.50012-7","volume-title":"Biochemical Actions of Hormones","author":"Eisen H. J.","year":"1983","unstructured":"Eisen H. J., Hannah R. R., Legraverend C., Okey A. B., Nebert D. W. The Ah receptor: controlling factor in the induction of drug-metabolizing enzymes by chemical carcinogens and other environmental pollutant. Biochemical Actions of Hormones, G. Litwack. Academic Press, New York 1983; Vol. 10: 227"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)69128-3"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)86026-X"},{"key":"e_1_2_1_49_1","article-title":"Family and population study of the genetic polymorphism of debrisoquine oxidation in a white British populatio","volume":"102","author":"Evans D. A. P.","year":"1980","unstructured":"Evans D. A. P., Mahgoub A., Sloan T. P., Idle J. R., Smith R. L. Family and population study of the genetic polymorphism of debrisoquine oxidation in a white British populatio. J. Med. Genet. 1980; 102","journal-title":"J. Med. Genet."},{"key":"e_1_2_1_50_1","unstructured":"Fagan J. B. Pastewka J. V. Chalberg S. R. Guzuka F. Guengerich F. P. Gelboin H. V. The mRNAs encoding cytochromes P-450bnf\/mc and P-450isf\/bnf-g are structurally distinct and are induced with different kinetic submitted for publication"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.45.030183.000315"},{"key":"e_1_2_1_52_1","volume-title":"Molecular Evolution","author":"Fitch W. M","year":"1976","unstructured":"Fitch W. M. Molecular evolutionary clock. Molecular Evolution, F. Ayala. Sinauer Associates, Inc., Sudnerland, Mass 1976; 161"},{"key":"e_1_2_1_53_1","first-page":"2092","article-title":"Protein evolution and the molecular cloc","volume":"35","author":"Fitch W. M.","year":"1976","unstructured":"Fitch W. M., Langley C. M. Protein evolution and the molecular cloc. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1976; 35: 2092","journal-title":"Fed. Proc. Fed. Am. Soc. Exp. Biol."},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.9.2793"},{"key":"e_1_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.jbchem.a133389"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)44681-3"},{"issue":"10","key":"e_1_2_1_57_1","first-page":"387","article-title":"Evidence for the presence of cholesterol side-chain cleavage cytochrome P-450 and adrenodoxin in fresh granulosa cell","volume":"258","author":"Funkenstein B.","year":"1983","unstructured":"Funkenstein B., Waterman M. R., Masters B. S. S., Simpson E. R. Evidence for the presence of cholesterol side-chain cleavage cytochrome P-450 and adrenodoxin in fresh granulosa cell. J. Biol. Chem. 1983; 258(10)387","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_58_1","volume-title":"The Induction of Drug Metabolism","author":"Gelboin H. V.","year":"1979","unstructured":"Gelboin H. V., Whitlock J. P., Jr. On the mechanism of mixed function oxidase inductio. The Induction of Drug Metabolism, R. W. Estabrook, E. Lindenlaub. F. K. Schattauer Verlag, Stuttgart 1979; 67"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pa.12.040172.000421"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90014-4"},{"key":"e_1_2_1_61_1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0026-895X(25)15058-X","article-title":"Differential induction of two 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-inducible forms of cytochrome P-450 in extrahepatic verses hepatic tissue","volume":"25","author":"Goldstein J. A.","year":"1984","unstructured":"Goldstein J. A., Linko P. Differential induction of two 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-inducible forms of cytochrome P-450 in extrahepatic verses hepatic tissue. Mol. Pharmacol. 1984; 25: 185","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)83872-3"},{"key":"e_1_2_1_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)89176-1"},{"key":"e_1_2_1_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(84)90057-X"},{"key":"e_1_2_1_65_1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0026-895X(25)15074-8","article-title":"Structural gene products of the Ah locus. Transcriptional regulation of cytochrome P1-450 and P3-450 mRNA levels by 3-methylcholanthren","volume":"26","author":"Gonzalez F. J.","year":"1984","unstructured":"Gonzalez F. J., Tukey R. H., Nebert D. W. Structural gene products of the Ah locus. Transcriptional regulation of cytochrome P1-450 and P3-450 mRNA levels by 3-methylcholanthren. Mol. Pharmacol. 1984; 26: 117","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/93.3.807"},{"key":"e_1_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00266a045"},{"key":"e_1_2_1_68_1","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0026-895X(25)11539-3","article-title":"Immunological comparison of hepatic and extrahepatic cytochromes P-45","volume":"15","author":"Guengerich F. P.","year":"1979","unstructured":"Guengerich F. P., Mason P. S. Immunological comparison of hepatic and extrahepatic cytochromes P-45. Mol. Pharmacol. 1979; 15: 154","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_69_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00536a035"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(77)90026-0"},{"key":"e_1_2_1_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1978.tb12697.x"},{"key":"e_1_2_1_72_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.8138129"},{"key":"e_1_2_1_73_1","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1016\/S0021-9258(19)42875-5","article-title":"Regulation and properties of a sex-specific hydroxylase system in female rat liver microsomes active on steroid sulfates. I. General characteristic","volume":"249","author":"Gustafsson J.-A.","year":"1974","unstructured":"Gustafsson J.-A., Ingelman-Sundberg M. Regulation and properties of a sex-specific hydroxylase system in female rat liver microsomes active on steroid sulfates. I. General characteristic. J. Biol. Chem. 1974; 249: 1940","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_74_1","doi-asserted-by":"crossref","first-page":"3451","DOI":"10.1016\/S0021-9258(19)41536-6","article-title":"Regulation and substrate specificity of a steroid sulfate specific hydroxylase system in female rat liver microsome","volume":"250","author":"Gustafsson J.-A.","year":"1975","unstructured":"Gustafsson J.-A., Ingelman-Sundberg M. Regulation and substrate specificity of a steroid sulfate specific hydroxylase system in female rat liver microsome. J. Biol. Chem. 1975; 250: 3451","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_75_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-98-4-922"},{"key":"e_1_2_1_76_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.45.030183.000411"},{"key":"e_1_2_1_77_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-95-3-891"},{"key":"e_1_2_1_78_1","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0021-9258(19)42988-8","article-title":"Irreversible androgenic programming at birth of microsomal and soluble rat liver enzymes active on 4-androstene-3, 17-dione and 5\u03b1-androstane-3\u03b1-,17\u03b2-dio","volume":"249","author":"Gustafsson J.-A.","year":"1974","unstructured":"Gustafsson J.-A., Stenberg A. Irreversible androgenic programming at birth of microsomal and soluble rat liver enzymes active on 4-androstene-3, 17-dione and 5\u03b1-androstane-3\u03b1-,17\u03b2-dio. J. Biol. Chem. 1974; 249: 711","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_79_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.5.1462"},{"key":"e_1_2_1_80_1","first-page":"5131","article-title":"Immunochemical detection and quantitation of microsomal cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate: cytochrome P-450 reductase in the rat ventral prostat","volume":"43","author":"Haaparanta T.","year":"1983","unstructured":"Haaparanta T., Halpert J., Glaumann H., Gustafsson J.-A. Immunochemical detection and quantitation of microsomal cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate: cytochrome P-450 reductase in the rat ventral prostat. Cancer Res. 1983; 43: 5131","journal-title":"Cancer Res."},{"key":"e_1_2_1_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(82)91053-1"},{"key":"e_1_2_1_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(84)90202-9"},{"key":"e_1_2_1_83_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.14.4298"},{"key":"e_1_2_1_84_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.1.373"},{"key":"e_1_2_1_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01542983"},{"key":"e_1_2_1_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01543050"},{"key":"e_1_2_1_87_1","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1016\/S0021-9258(18)89662-4","article-title":"Mutations affecting the regulation of transcription of the cytochrome P1-450 gene in the mouse Hepa-1-cell line (1985","volume":"260","author":"Hankinson O.","year":"1985","unstructured":"Hankinson O., Anderson R. D., Birren B. W., Sander F., Negishi M, Nebert D. W. Mutations affecting the regulation of transcription of the cytochrome P1-450 gene in the mouse Hepa-1-cell line (1985. J. Biol. Chem. 1985; 260: 1798","journal-title":"J. Biol. Chem."},{"issue":"10","key":"e_1_2_1_88_1","first-page":"182","article-title":"Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone-16\u2013\u03b1 carbonitrile: characterization of its mRNA, gene and induction respons","volume":"258","author":"Hardwick J. P.","year":"1983","unstructured":"Hardwick J. P., Gonzales F. J., Kasper C. B. Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone-16\u2013\u03b1 carbonitrile: characterization of its mRNA, gene and induction respons. J. Biol. Chem. 1983; 258(10)182","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(20)82030-4"},{"key":"e_1_2_1_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)33722-5"},{"issue":"14","key":"e_1_2_1_91_1","first-page":"988","article-title":"The covalent structure of rabbit phenobarbital-induced cytochrome P-450. Partial amino acid sequence and order of cyanogen bromide peptide","volume":"257","author":"Heinemann F. S.","year":"1982","unstructured":"Heinemann F. S., Ozols J. The covalent structure of rabbit phenobarbital-induced cytochrome P-450. Partial amino acid sequence and order of cyanogen bromide peptide. J. Biol. Chem. 1982; 257(14)988","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-128X(66)90137-1"},{"key":"e_1_2_1_93_1","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0026-895X(25)14931-6","article-title":"Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16\u03b1-carbonitrile or other steroidal or non-steroidal agent","volume":"21","author":"Heuman D. M.","year":"1982","unstructured":"Heuman D. M., Gallagher E. J., Barwick J. L., Elshourbagy N. A., Guzelian P. S. Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16\u03b1-carbonitrile or other steroidal or non-steroidal agent. Mol. Pharmacol. 1982; 21: 753","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2760(81)90026-6"},{"key":"e_1_2_1_95_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ge.09.120175.001513"},{"key":"e_1_2_1_96_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1983.tb07524.x"},{"key":"e_1_2_1_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)91022-7"},{"key":"e_1_2_1_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-128X(69)90042-7"},{"key":"e_1_2_1_99_1","first-page":"1","volume-title":"Genetic Engineering","author":"Jeffreys A. J","year":"1981","unstructured":"Jeffreys A. J. Recent studies of gene evolution using recombinant DN. Genetic Engineering, R. Williamson. Academic Press, New York 1981; Vol. 2: 1"},{"key":"e_1_2_1_100_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.18.5628"},{"key":"e_1_2_1_101_1","doi-asserted-by":"publisher","DOI":"10.1159\/000455531"},{"key":"e_1_2_1_102_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1982.tb01430.x"},{"key":"e_1_2_1_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(83)90087-5"},{"key":"e_1_2_1_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/308513a0"},{"key":"e_1_2_1_105_1","doi-asserted-by":"publisher","DOI":"10.3109\/03602537408993737"},{"key":"e_1_2_1_106_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.6.1649"},{"key":"e_1_2_1_107_1","first-page":"1465","article-title":"Molecular cloning of a complementary DNA to 3-methylcholanthrene-inducible cytochrome P-450 mRNA from rat live","volume":"94","author":"Kawajiri K.","year":"1983","unstructured":"Kawajiri K., Sogawa K., Gotoh O., Tagashira Y., Muramatsu M., Fujii-Kuriyama Y. Molecular cloning of a complementary DNA to 3-methylcholanthrene-inducible cytochrome P-450 mRNA from rat live. J. Biochem. 1983; 94: 1465","journal-title":"J. Biochem."},{"key":"e_1_2_1_108_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/12.6.2917"},{"issue":"10","key":"e_1_2_1_109_1","first-page":"705","article-title":"The murine Ah locus. Comparison of the complete cytochrome P1-450 and PJ-450 cDNA nucleotide and amino acid sequence","volume":"259","author":"Kimura S.","year":"1984","unstructured":"Kimura S., Gonzalez F. J., Nebert D. W. The murine Ah locus. Comparison of the complete cytochrome P1-450 and PJ-450 cDNA nucleotide and amino acid sequence. J. Biol. Chem. 1984; 259(10)705","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_110_1","doi-asserted-by":"publisher","DOI":"10.1038\/307745a0"},{"key":"e_1_2_1_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/289144a0"},{"key":"e_1_2_1_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(77)90233-9"},{"issue":"14","key":"e_1_2_1_113_1","first-page":"921","article-title":"Adrenodoxin biosynthesis by bovine adrenal cells in monolayer cultur","volume":"257","author":"Kramer R. E.","year":"1982","unstructured":"Kramer R. E., Anderson C. M., Peterson J. A., Simpson E. R., Waterman M. R. Adrenodoxin biosynthesis by bovine adrenal cells in monolayer cultur. J. Biol. Chem. 1982; 257(14)921","journal-title":"J. Biol. Chem."},{"issue":"14","key":"e_1_2_1_114_1","first-page":"921","article-title":"Adrenodoxin biosynthesis by bovine adrenal cells in monolayer culture: induction by adrenocorticotropi","volume":"257","author":"Kramer R. E.","year":"1982","unstructured":"Kramer R. E., Anderson C. M., Peterson J. A., Simpson E. R., Waterman M. R. Adrenodoxin biosynthesis by bovine adrenal cells in monolayer culture: induction by adrenocorticotropi. J. Biol. Chem. 1982; 257(14)921","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(82)90106-0"},{"key":"e_1_2_1_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)43515-0"},{"key":"e_1_2_1_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)32820-5"},{"key":"e_1_2_1_118_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.16.4997"},{"key":"e_1_2_1_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)86205-1"},{"issue":"11","key":"e_1_2_1_120_1","first-page":"280","article-title":"Cloned cytochrome P-450 cDNA, nucleotide sequence and homology to multiple phenobarbital-induced mRNA specie","volume":"258","author":"Kumar A.","year":"1983","unstructured":"Kumar A., Raphael C., Adesnik M. Cloned cytochrome P-450 cDNA, nucleotide sequence and homology to multiple phenobarbital-induced mRNA specie. J. Biol. Chem. 1983; 258(11)280","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_121_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.jbchem.a134660"},{"key":"e_1_2_1_122_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00307a039"},{"key":"e_1_2_1_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90429-4"},{"key":"e_1_2_1_124_1","volume-title":"Biochemistry, Biophysics and Regulation of Cytochrome P-450","author":"Lefevre A.","year":"1980","unstructured":"Lefevre A., Hall P. F., Hanson A., Gustafsson J.-A. Partial purification of the 15\u2013\u03b2-hydroxylase in female rat live. Biochemistry, Biophysics and Regulation of Cytochrome P-450, J. A. Gustafsson, J. Carlstedt-Duke, A. Mode, J. Rather. Elsevier, Amsterdam 1980; 533"},{"key":"e_1_2_1_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(20)65155-9"},{"key":"e_1_2_1_126_1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/genetics\/107.3.447","article-title":"Aryl hydrocarbon hydroxylase induction by benzo[a]anthracene: regulatory gene localized to the distal portion of mouse chromosome 1","volume":"107","author":"Legraverend C.","year":"1984","unstructured":"Legraverend C., Karenlampi S. O., Bigelow S. W., Lalley P. A., Kozak C. A., Womack J. E., Nebert D. W. Aryl hydrocarbon hydroxylase induction by benzo[a]anthracene: regulatory gene localized to the distal portion of mouse chromosome 1. Genetics 1984; 107: 447","journal-title":"Genetics"},{"key":"e_1_2_1_127_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00297a005"},{"issue":"11","key":"e_1_2_1_128_1","first-page":"165","article-title":"Differential induction and tissue specific expression of closely related members of the phenobarbital-inducible rabbit cytochrome P-450 gene famil","volume":"259","author":"Leighton J. K.","year":"1984","unstructured":"Leighton J. K., Kemper B. Differential induction and tissue specific expression of closely related members of the phenobarbital-inducible rabbit cytochrome P-450 gene famil. J. Biol. Chem. 1984; 259(11)165","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_129_1","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S0026-895X(25)10626-3","article-title":"Neonatal imprinting and the turnover of cytochrome P-450 in rat live","volume":"11","author":"Levin W.","year":"1975","unstructured":"Levin W., Ryan D., Kuntzman R., Conney A. H. Neonatal imprinting and the turnover of cytochrome P-450 in rat live. Mol. Pharmacol. 1975; 11: 190","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_130_1","volume-title":"Evolution of Genes and Proteins","author":"Li W.-M","year":"1983","unstructured":"Li W.-M. Evolution of duplicate genes and pseudogene. Evolution of Genes and Proteins, M. Nei, R. K. Koehn. Sinauer Associates, Sunderland, Mass 1983; 14"},{"key":"e_1_2_1_131_1","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0026-895X(25)14556-2","article-title":"Differential induction by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin of multiple forms of rabbit microsomal cytochrome P-450: evidence for tissue specificit","volume":"18","author":"Liem H. H.","year":"1980","unstructured":"Liem H. H., Muller-Eberhard U., Johnson E. F. Differential induction by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin of multiple forms of rabbit microsomal cytochrome P-450: evidence for tissue specificit. Mol. Pharmacol. 1980; 18: 565","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(82)90045-9"},{"key":"e_1_2_1_133_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6774414"},{"key":"e_1_2_1_134_1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0031-6997(25)06835-8","article-title":"Multiplicity of mammalian cytochromes P-45","volume":"31","author":"Lu A. Y. H.","year":"1980","unstructured":"Lu A. Y. H., West S. B. Multiplicity of mammalian cytochromes P-45. Pharmacol. Rev. 1980; 31: 277","journal-title":"Pharmacol. Rev."},{"key":"e_1_2_1_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)91430-1"},{"key":"e_1_2_1_136_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1982.tb06518.x"},{"key":"e_1_2_1_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(83)90557-X"},{"key":"e_1_2_1_138_1","doi-asserted-by":"publisher","DOI":"10.1038\/306792a0"},{"issue":"15","key":"e_1_2_1_139_1","first-page":"245","article-title":"Boundaries of gene conversion within the duplicated human \u03b1-globin genes. Concerted evolution by segmential recombinatio","volume":"258","author":"Michelson A. M.","year":"1983","unstructured":"Michelson A. M., Orkin S. H. Boundaries of gene conversion within the duplicated human \u03b1-globin genes. Concerted evolution by segmential recombinatio. J. Bid. Chem. 1983; 258(15)245","journal-title":"J. Bid. Chem."},{"key":"e_1_2_1_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)32693-0"},{"key":"e_1_2_1_141_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.4.2143"},{"key":"e_1_2_1_142_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00274a036"},{"key":"e_1_2_1_143_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.13.3958"},{"key":"e_1_2_1_144_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-113-4-1250"},{"key":"e_1_2_1_145_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-108-6-2103"},{"key":"e_1_2_1_146_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.5.4.698-704.1985"},{"key":"e_1_2_1_147_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.15.4647"},{"key":"e_1_2_1_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)32752-2"},{"key":"e_1_2_1_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(80)90319-8"},{"key":"e_1_2_1_150_1","first-page":"1517","article-title":"Contributions of cytoplasmic free and membrane-bound ribosomes to the synthesis of mitochondrial cytochrome P-450(scc) and P-450(11\u03b2) and microsomal cytochrome P-450(C-21) in bovine adrenal corte","volume":"94","author":"Nabi N.","year":"1983","unstructured":"Nabi N., Kominami S., Takemori S., Omura T. Contributions of cytoplasmic free and membrane-bound ribosomes to the synthesis of mitochondrial cytochrome P-450(scc) and P-450(11\u03b2) and microsomal cytochrome P-450(C-21) in bovine adrenal corte. J. Biochem. 1983; 94: 1517","journal-title":"J. Biochem."},{"key":"e_1_2_1_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(80)90318-6"},{"key":"e_1_2_1_152_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1983.tb07525.x"},{"key":"e_1_2_1_153_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00849277"},{"key":"e_1_2_1_154_1","doi-asserted-by":"crossref","first-page":"6373","DOI":"10.1016\/S0021-9258(18)62620-1","article-title":"Genetic differences in the extent of aryl hydrocarbon hydroxylase induction in mouse fetal cell culture","volume":"245","author":"Nebert D. W.","year":"1970","unstructured":"Nebert D. W., Bausserman L. L. Genetic differences in the extent of aryl hydrocarbon hydroxylase induction in mouse fetal cell culture. J. Biol. Chem. 1970; 245: 6373","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(84)90446-5"},{"key":"e_1_2_1_156_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pa.21.040181.002243"},{"key":"e_1_2_1_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(69)90253-7"},{"key":"e_1_2_1_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/newbio236107a0"},{"key":"e_1_2_1_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(82)90523-8"},{"key":"e_1_2_1_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2660(08)60296-5"},{"key":"e_1_2_1_161_1","doi-asserted-by":"crossref","first-page":"4791","DOI":"10.1016\/S0021-9258(17)30459-3","article-title":"Coordinated polypeptide synthesis and insertion of protoheme in cytochrome P-450 during development of endoplasmic reticulum membrane","volume":"253","author":"Negishi M.","year":"1978","unstructured":"Negishi M., Kreibich G. Coordinated polypeptide synthesis and insertion of protoheme in cytochrome P-450 during development of endoplasmic reticulum membrane. J. Biol. Chem. 1978; 253: 4791","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_162_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1981.tb06243.x"},{"issue":"11","key":"e_1_2_1_163_1","first-page":"015","article-title":"Structural gene products of Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthren","volume":"254","author":"Negishi M.","year":"1979","unstructured":"Negishi M., Nebert D. W. Structural gene products of Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthren. J. Biol. Chem. 1979; 254(11)015","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)69727-9"},{"key":"e_1_2_1_165_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.2.800"},{"key":"e_1_2_1_166_1","volume-title":"The Metabolic Basis of Inherited Disease","author":"New M. I.","year":"1982","unstructured":"New M. I., Dupont B., Grumbach K., Levine L. S. The Metabolic Basis of Inherited Disease, J. B. Stanbury, J. B. Wyngaarden, D. S. Fredrickson, J. L. Goldstein, M. S. Brown. McGraw-Hill, New York 1982; 973"},{"key":"e_1_2_1_167_1","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0026-895X(25)10638-X","article-title":"Induction of aryl hydrocarbon hydroxylase activity in various cell cultures by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxi","volume":"11","author":"Niwa A.","year":"1975","unstructured":"Niwa A., Kumaki K., Nebert D. W. Induction of aryl hydrocarbon hydroxylase activity in various cell cultures by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxi. Mol. Pharmacol. 1975; 11: 398","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_168_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-112-3-1076"},{"key":"e_1_2_1_169_1","first-page":"1711","article-title":"Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450s from adrenal corte","volume":"94","author":"Ogishima T.","year":"1983","unstructured":"Ogishima T., Okada Y., Kominami S., Takemori S., Omura T. Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450s from adrenal corte. J. Biochem. 1983; 94: 1711","journal-title":"J. Biochem."},{"key":"e_1_2_1_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)43407-7"},{"key":"e_1_2_1_171_1","volume-title":"Cytochrome P-450. Biophys. Biochem. and Environmental Implications","author":"Ohyama T.","year":"1982","unstructured":"Ohyama T., Tukey R. H., Nebert D. W., Negishi M. Genetic regulation of mouse liver microsomal P2-450 induction by isosafrole and 3-methylcholanthren. Cytochrome P-450. Biophys. Biochem. and Environmental Implications, E. Hietanen, M. Laitinen, O. Hanninen. Elsevier, Amsterdam 1982; 177"},{"issue":"11","key":"e_1_2_1_172_1","first-page":"636","article-title":"Regulatory gene product of the Ah locu","volume":"254","author":"Okey A. B.","year":"1979","unstructured":"Okey A. B., Bondy G. P., Mason M. E., Kahl G. F., Eisen H. J., Guenthner T. M., Nebert D. W. Regulatory gene product of the Ah locu. J. Biol. Chem. 1979; 254(11)636","journal-title":"J. Biol. Chem."},{"issue":"11","key":"e_1_2_1_173_1","first-page":"415","article-title":"Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in continuous cell culture line","volume":"255","author":"Okey A. B.","year":"1980","unstructured":"Okey A. B., Bondy G. P., Mason M. E., Nebert D. W., Forster-Gibson C. J., Muncan J., Dufresne M. J. Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in continuous cell culture line. J. Biol. Chem. 1980; 255(11)415","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_174_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1982.tb06834.x"},{"key":"e_1_2_1_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90471-3"},{"key":"e_1_2_1_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(83)90478-2"},{"key":"e_1_2_1_177_1","volume-title":"The Induction of Drug Metabolism","author":"Omura T","year":"1979","unstructured":"Omura T. Biosynthesis and drug-induced increase of microsomal enzyme. The Induction of Drug Metabolism, R. W. Estabrook, E. Linden. F. K. Schattauer Verlag, Stuttgart 1979; 161"},{"key":"e_1_2_1_178_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.25.3.627"},{"issue":"11","key":"e_1_2_1_179_1","first-page":"405","article-title":"Amino acid sequence of analogous peptide from two forms of cytochrome P-45","volume":"256","author":"Ozols J.","year":"1981","unstructured":"Ozols J., Heinmann F. S., Johnson E. F. Amino acid sequence of analogous peptide from two forms of cytochrome P-45. J. Biol. Chem. 1981; 256(11)405","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_180_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(78)90023-0"},{"key":"e_1_2_1_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-2797(80)90147-7"},{"key":"e_1_2_1_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(80)90339-1"},{"key":"e_1_2_1_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(83)90024-3"},{"key":"e_1_2_1_184_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7414320"},{"key":"e_1_2_1_185_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(83)90034-3"},{"key":"e_1_2_1_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(82)90681-7"},{"key":"e_1_2_1_187_1","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S0026-895X(25)14014-5","article-title":"Chlorinated dibenzo-p-dioxins: potent inducers of \u03b1-aminolevulinic acid synthetase and aryl hydrocarbon hydroxylase. II. A study of the structure-activity relationshi","volume":"9","author":"Poland A.","year":"1973","unstructured":"Poland A., Glover E. Chlorinated dibenzo-p-dioxins: potent inducers of \u03b1-aminolevulinic acid synthetase and aryl hydrocarbon hydroxylase. II. A study of the structure-activity relationshi. Mol. Pharmacol. 1973; 9: 736","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_188_1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0026-895X(25)10636-6","article-title":"Genetic expression of aryl hydrocarbon hydroxylase by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. Evidence for a receptor mutation in genetically non-responsive mic","volume":"11","author":"Poland A.","year":"1975","unstructured":"Poland A., Glover E. Genetic expression of aryl hydrocarbon hydroxylase by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. Evidence for a receptor mutation in genetically non-responsive mic. Mol. Pharmacol. 1975; 11: 389","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)33205-2"},{"key":"e_1_2_1_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(20)79769-3"},{"key":"e_1_2_1_191_1","doi-asserted-by":"publisher","DOI":"10.1038\/263211a0"},{"key":"e_1_2_1_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(73)90427-X"},{"key":"e_1_2_1_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90016-8"},{"key":"e_1_2_1_194_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.21.6542"},{"key":"e_1_2_1_195_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)34875-0"},{"key":"e_1_2_1_196_1","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0026-895X(25)14410-6","article-title":"The relationship between increases in the hepatic content of cytochrome P-450, form 5, and the metabolism of aromatic amines to mutagenic products following treatment of rabbits with phenobarbita","volume":"24","author":"Robertson I. G.C.","year":"1983","unstructured":"Robertson I. G.C., Serabjit-Singh C., Croft J., Philpot R. M. The relationship between increases in the hepatic content of cytochrome P-450, form 5, and the metabolism of aromatic amines to mutagenic products following treatment of rabbits with phenobarbita. Mol. Pharmacol. 1983; 24: 156","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_197_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(20)79896-0"},{"key":"e_1_2_1_198_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.45.030183.000345"},{"key":"e_1_2_1_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(84)90489-2"},{"key":"e_1_2_1_200_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)43594-0"},{"key":"e_1_2_1_201_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)34211-4"},{"key":"e_1_2_1_202_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)43925-2"},{"key":"e_1_2_1_203_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(82)90212-0"},{"key":"e_1_2_1_204_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)43508-3"},{"key":"e_1_2_1_205_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)83602-5"},{"key":"e_1_2_1_206_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6767272"},{"key":"e_1_2_1_207_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)44531-5"},{"key":"e_1_2_1_208_1","doi-asserted-by":"publisher","DOI":"10.1139\/o83-088"},{"key":"e_1_2_1_209_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)69810-8"},{"key":"e_1_2_1_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(80)90426-2"},{"key":"e_1_2_1_211_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.16.5066"},{"key":"e_1_2_1_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(81)90175-6"},{"key":"e_1_2_1_213_1","doi-asserted-by":"publisher","DOI":"10.1530\/acta.0.0780294"},{"key":"e_1_2_1_214_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.1984.3.129"},{"key":"e_1_2_1_215_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90331-8"},{"key":"e_1_2_1_216_1","volume-title":"Molecular Evolution, Protein Polymorphism and the Neutral Theory","author":"Takahata N","year":"1982","unstructured":"Takahata N. The disappearance of duplicate gene expressio. Molecular Evolution, Protein Polymorphism and the Neutral Theory, M. Kimura. Japan Scientific Societies Press, Tokyo 1982; 169, Springer-Verlag. Berlin"},{"key":"e_1_2_1_217_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.21.6552"},{"key":"e_1_2_1_218_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)32871-5"},{"key":"e_1_2_1_219_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00486177"},{"key":"e_1_2_1_220_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(79)90122-X"},{"key":"e_1_2_1_221_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00486400"},{"key":"e_1_2_1_222_1","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S0026-895X(25)12445-0","article-title":"Accessibility of cytochrome P-450 in microsomal membranes: inhibition of metabolism by antibodies to cytochrome P-45","volume":"13","author":"Thomas P. E.","year":"1977","unstructured":"Thomas P. E., Lu A. Y. H., West S. B., Ryan D., Miwa G. T., Levin W. Accessibility of cytochrome P-450 in microsomal membranes: inhibition of metabolism by antibodies to cytochrome P-45. Mol. Pharmacol. 1977; 13: 819","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_223_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)70085-4"},{"key":"e_1_2_1_224_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)32664-4"},{"key":"e_1_2_1_225_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)43181-4"},{"key":"e_1_2_1_226_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(83)90095-4"},{"key":"e_1_2_1_227_1","doi-asserted-by":"publisher","DOI":"10.1038\/302591a0"},{"key":"e_1_2_1_228_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)90527-X"},{"key":"e_1_2_1_229_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(82)90427-5"},{"key":"e_1_2_1_230_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.10.3163"},{"key":"e_1_2_1_231_1","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S0026-895X(25)15195-X","article-title":"Quantitation of cytochrome P1-450 mRNA with the use of a cloned DNA probe: effects of various inducers in C57BL\/6N and DBA\/2N mic","volume":"22","author":"Tukey R. H.","year":"1982","unstructured":"Tukey R. H., Negishi H., Nebert D. W. Quantitation of cytochrome P1-450 mRNA with the use of a cloned DNA probe: effects of various inducers in C57BL\/6N and DBA\/2N mic. Mol. Pharmacol. 1982; 22: 779","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_232_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00320a016"},{"key":"e_1_2_1_233_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)69085-X"},{"key":"e_1_2_1_234_1","first-page":"6031","article-title":"Single step phototoxic selection procedure isolating cells that possess aryl hydrocarbon hydroxylas","volume":"43","author":"Van Gurp J. R.","year":"1983","unstructured":"Van Gurp J. R., Hankinson O. Single step phototoxic selection procedure isolating cells that possess aryl hydrocarbon hydroxylas. Cancer Res. 1983; 43: 6031","journal-title":"Cancer Res."},{"key":"e_1_2_1_235_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.4.8.1597-1604.1984"},{"key":"e_1_2_1_236_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00533a033"},{"key":"e_1_2_1_237_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00267a038"},{"key":"e_1_2_1_238_1","doi-asserted-by":"publisher","DOI":"10.1038\/306557a0"},{"key":"e_1_2_1_239_1","doi-asserted-by":"publisher","DOI":"10.3109\/00498258209038949"},{"key":"e_1_2_1_240_1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0021-9258(17)42574-9","article-title":"Rat hepatic cytochrome P-450 isoenzyme 2c: identification as a male-specific, developmentally-induced steroid 16\u03b1-hydroxylase and comparison to a female specific isoenzym","volume":"259","author":"Waxman D","year":"1984","unstructured":"Waxman D. Rat hepatic cytochrome P-450 isoenzyme 2c: identification as a male-specific, developmentally-induced steroid 16\u03b1-hydroxylase and comparison to a female specific isoenzym. J. Biol. Chem. 1984; 259: 15","journal-title":"J. Biol. Chem."},{"issue":"11","key":"e_1_2_1_241_1","first-page":"937","article-title":"Regio selectivity and stereo selectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat live","volume":"258","author":"Waxman D. J.","year":"1983","unstructured":"Waxman D. J., Ko A., Walsh C. Regio selectivity and stereo selectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat live. J. Biol. Chem. 1983; 258(11)937","journal-title":"J. Biol. Chem."},{"issue":"10","key":"e_1_2_1_242_1","first-page":"446","article-title":"Phenobarbital-induced rat liver cytochrome P-45","volume":"257","author":"Waxman D. J.","year":"1982","unstructured":"Waxman D. J., Walsh C. Phenobarbital-induced rat liver cytochrome P-45. J. Biol. Chem. 1982; 257(10)446","journal-title":"J. Biol. Chem."},{"key":"e_1_2_1_243_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00289a035"},{"key":"e_1_2_1_244_1","doi-asserted-by":"publisher","DOI":"10.1038\/297289a0"},{"key":"e_1_2_1_245_1","doi-asserted-by":"publisher","DOI":"10.1038\/307747a0"},{"key":"e_1_2_1_246_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.7.1986"},{"key":"e_1_2_1_247_1","doi-asserted-by":"publisher","DOI":"10.1038\/312465a0"},{"key":"e_1_2_1_248_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.49.070180.001531"},{"key":"e_1_2_1_249_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)43554-X"},{"key":"e_1_2_1_250_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2795(80)90082-3"},{"key":"e_1_2_1_251_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)50812-7"},{"key":"e_1_2_1_252_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)50462-2"},{"key":"e_1_2_1_253_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)32132-X"},{"key":"e_1_2_1_254_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)50463-4"},{"key":"e_1_2_1_255_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.16.5031"},{"key":"e_1_2_1_256_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/12.6.2929"},{"key":"e_1_2_1_257_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.8.2623"},{"key":"e_1_2_1_258_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-63-6-887"},{"key":"e_1_2_1_259_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6356359"},{"key":"e_1_2_1_260_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00270a021"},{"key":"e_1_2_1_261_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.5.1169"}],"container-title":["Critical Reviews in Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/10409238609084657","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T18:43:03Z","timestamp":1770403383000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3109\/10409238609084657"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,1]]},"references-count":260,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1986,1]]}},"alternative-id":["10.3109\/10409238609084657"],"URL":"https:\/\/doi.org\/10.3109\/10409238609084657","relation":{},"ISSN":["1040-8355"],"issn-type":[{"value":"1040-8355","type":"print"}],"subject":[],"published":{"date-parts":[[1986,1]]}}}