{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T01:31:33Z","timestamp":1770946293765,"version":"3.50.1"},"reference-count":66,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Leukemia &amp; Lymphoma"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.3109\/10428190109097764","type":"journal-article","created":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T14:52:35Z","timestamp":1204901555000},"page":"1359-1366","source":"Crossref","is-referenced-by-count":1,"title":["The Presence of Circulating Clonal CD19\n                    <sup>+<\/sup>\n                    Cells in Multiple Myeloma"],"prefix":"10.1080","volume":"42","author":[{"given":"Thomas","family":"Rasmussen","sequence":"first","affiliation":[{"name":"Department of Hematology L, Herlev Hospital, University of Copenhagen, Herlev, 2730, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1985.tb00792.x"},{"issue":"1","key":"e_1_2_1_3_1","first-page":"67","article-title":"Biology and therapy of multiple myeloma (1996)","volume":"34","author":"Barlogie B.","year":"1997","unstructured":"Barlogie B., Jagannath S., Epstein J., Munshi N., Siegel D., Desikan K. R., Feinman R., Hsu R-L., Von Bremen K., Tricot G. Biology and therapy of multiple myeloma (1996). Seminars in Hematology 1997; 34((Suppl. 1))67\u201372","journal-title":"Seminars in Hematology"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199607113350204"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V90.9.3751"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1182\/blood.V89.5.1824","article-title":"CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements","volume":"89","author":"Szczepek A. J.","year":"1997","unstructured":"Szczepek A. J., Bergsagel P. L., Axelsson L., Brown C. B., Belch A. R., Pilarski L. M. CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements. Blood 1997; 89: 1824\u20131833","journal-title":"Blood"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V85.2.436.436"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428199609054775"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428199509056847"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V83.3.724.724"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(18)30346-0"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V92.8.2844"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V90.1.340"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V87.5.1972.1972"},{"key":"e_1_2_1_15_1","first-page":"1655","article-title":"Immunophenotypic characterization of plasma cells from monoclonal gammopathy of undetermined significance patients. Implications for the differential diagnosis between MGUS and multiple myeloma","volume":"152","author":"Ocqueteau M.","year":"1998","unstructured":"Ocqueteau M., Orfao A., Almeida J., Blade J., Gonzalez M., Garcia-Sanz R., Lopez-Berges C., Moro M. J., Hernandez J., Escribano L., Caballero D., Rozman M., San M. J. Immunophenotypic characterization of plasma cells from monoclonal gammopathy of undetermined significance patients. Implications for the differential diagnosis between MGUS and multiple myeloma. American Journal of Pathology 1998; 152: 1655\u20131665","journal-title":"American Journal of Pathology"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)61350-0"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V81.10.2658.2658"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1996.tb08993.x"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V84.8.2597.2597"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428199509059611"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1990.tb02579.x"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1991.tb08570.x"},{"key":"e_1_2_1_23_1","first-page":"651","article-title":"Minimal residual disease after bone marrow transplantation for multiple myeloma: evidence for cure in long-term survivors","volume":"12","author":"Bird J. M.","year":"1993","unstructured":"Bird J. M., Russell N. H., Samson D. Minimal residual disease after bone marrow transplantation for multiple myeloma: evidence for cure in long-term survivors. Bone Marrow Transplantation 1993; 12: 651\u2013654","journal-title":"Bone Marrow Transplantation"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1994.tb04985.x"},{"key":"e_1_2_1_25_1","first-page":"1879","article-title":"Detection of circulating tumor cells in multiple myeloma by a PCR-based method","volume":"7","author":"Corradini P.","year":"1993","unstructured":"Corradini P., Voena C., Omede P., Astolfi M., Boccadoro M., Dalla-Favera R., Pileri A. Detection of circulating tumor cells in multiple myeloma by a PCR-based method. Leukemia 1993; 7: 1879\u20131882","journal-title":"Leukemia"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V80.7.1818.1818"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V85.6.1596.bloodjournal8561596"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1996.00381.x"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V80.9.2326.2326"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V82.1.202.bloodjournal821202"},{"key":"e_1_2_1_31_1","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.4049\/jimmunol.155.5.2487","article-title":"Myeloma Ig heavy chain V region sequences reveal prior antigenic selection and marked somatic mutation but no intraclonal diversity","volume":"155","author":"Vescio R. A.","year":"1995","unstructured":"Vescio R. A., Cao J., Hong C. H., Lee J. C., Wu C. H., Der D. M., Wu V., Newman R., Lichtenstein A. K., Berenson J. R. Myeloma Ig heavy chain V region sequences reveal prior antigenic selection and marked somatic mutation but no intraclonal diversity. Journal of Immunology 1995; 155: 2487\u20132497","journal-title":"Journal of Immunology"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1128\/cdli.2.1.44-52.1995"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02989586"},{"key":"e_1_2_1_34_1","first-page":"1948","article-title":"A CD10-positive subset of malignant cells is identified in multiple myeloma using PCR with patient-specific immunoglobulin gene primers","volume":"9","author":"Cao J.","year":"1995","unstructured":"Cao J., Vescio R. A., Rettig M. B., Hong C. H., Kim A., Lee J. C., Lichtenstein A. K., Berenson J. R. A CD10-positive subset of malignant cells is identified in multiple myeloma using PCR with patient-specific immunoglobulin gene primers. Leukemia 1995; 9: 1948\u20131953","journal-title":"Leukemia"},{"key":"e_1_2_1_35_1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1365-2141.1999.01301.x","article-title":"High numbers of clonal CD19+ cells in the peripheral blood of a patient with multiple myeloma","volume":"105","author":"Rasmussen T.","year":"1999","unstructured":"Rasmussen T., Kastrup J., Knudsen L. M., Johnsen H. E. High numbers of clonal CD19+ cells in the peripheral blood of a patient with multiple myeloma. British Journal of Haematology 1999; 105: 265\u2013267","journal-title":"British Journal of Haematology"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1999.01770.x"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/028418600750063479"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V76.9.1739.1739"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0320(19960615)26:2<113::AID-CYTO3>3.0.CO;2-H"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V88.5.1780.1780"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1997.72653.x"},{"key":"e_1_2_1_42_1","doi-asserted-by":"crossref","first-page":"3551","DOI":"10.1182\/blood.V94.10.3551.422k08_3551_3558","article-title":"Enforced CD19 expression leads to growth inhibition and reduced tumorigenicity","volume":"94","author":"Mahmoud M. S.","year":"1999","unstructured":"Mahmoud M. S., Fujii R., Ishikawa H., Kawano M. M. Enforced CD19 expression leads to growth inhibition and reduced tumorigenicity. Blood 1999; 94: 3551\u20133558","journal-title":"Blood"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V91.1.3"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.178.3.1023"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.178.3.1091"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1994.tb04872.x"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1999.01233.x"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.24.13931"},{"key":"e_1_2_1_49_1","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1182\/blood.V94.8.2583.420a05_2583_2589","article-title":"Monosomy 13 is associated with the transitin of monoclonal gammopathy of undetermined significance to multiple myeloma","volume":"94","author":"Avet-Loiseau H.","year":"1999","unstructured":"Avet-Loiseau H., Li J. Y., Morineau N., Facon T., Brigaudeau C., Harousseau J. L., Grosbois B., Bataille R. Monosomy 13 is associated with the transitin of monoclonal gammopathy of undetermined significance to multiple myeloma. Blood 1999; 94: 2586\u20132589","journal-title":"Blood"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-472X(00)00514-2"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.13.4357"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2400773"},{"key":"e_1_2_1_53_1","article-title":"Controversies surrounding the circulating clonotypic B-lymphocytes in multiple myeloma","author":"Rasmussen T.","year":"2001","unstructured":"Rasmussen T., Johnsen H. E. Controversies surrounding the circulating clonotypic B-lymphocytes in multiple myeloma. Blood 2001","journal-title":"Blood"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1999.01548.x"},{"key":"e_1_2_1_55_1","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1182\/blood.V92.8.2908","article-title":"Primary myeloma cells growing in SCGD-hu mice: a model for studying the biology and treatment of myeloma and its manifestations","volume":"92","author":"Yaccoby S.","year":"1998","unstructured":"Yaccoby S., Epstein J. Primary myeloma cells growing in SCGD-hu mice: a model for studying the biology and treatment of myeloma and its manifestations. Blood 1998; 92: 2908\u20132913","journal-title":"Blood"},{"key":"e_1_2_1_56_1","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1182\/blood.V94.10.3576.422k01_3576_3582","article-title":"The proliferative potential of myeloma plasma cells manifest in the SCID-hu host","volume":"94","author":"Yaccoby S.","year":"1999","unstructured":"Yaccoby S., Epstein J. The proliferative potential of myeloma plasma cells manifest in the SCID-hu host. Blood 1999; 94: 3576\u20133582","journal-title":"Blood"},{"key":"e_1_2_1_57_1","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1182\/blood.V94.3.1070.415k25_1070_1076","article-title":"VH gene analysis of IgM-secreting myeloma indicates an origin from a memory cell undergoing isotype switch events","volume":"94","author":"Sahota S.","year":"1999","unstructured":"Sahota S., Garand R., Mahroof R., Smith A., Juge-Morineau N., Stevenson F. K., Bataille R. VH gene analysis of IgM-secreting myeloma indicates an origin from a memory cell undergoing isotype switch events. Blood 1999; 94: 1070\u20131076","journal-title":"Blood"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1999.01603.x"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V91.7.2459"},{"key":"e_1_2_1_60_1","doi-asserted-by":"crossref","first-page":"4020","DOI":"10.1182\/blood.V95.12.4020","article-title":"Levels of circulating CD19+ cells in patients with multiple myeloma","volume":"95","author":"Rasmussen T.","year":"2000","unstructured":"Rasmussen T., Jensen L., Johnsen H. E. Levels of circulating CD19+ cells in patients with multiple myeloma. Blood 2000; 95: 4020\u20134021","journal-title":"Blood"},{"key":"e_1_2_1_61_1","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1182\/blood.V88.3.1125a.1125a","article-title":"Circulating clonal lymphocytes in myeloma determined by mRNA in situ hybridization","volume":"88","author":"Joshua D. E.","year":"1996","unstructured":"Joshua D. E., Brown R. D., Luo X. F., Gibson J. Circulating clonal lymphocytes in myeloma determined by mRNA in situ hybridization. Blood 1996; 88: 1125","journal-title":"Blood"},{"key":"e_1_2_1_62_1","first-page":"585","article-title":"In multiple myeloma, circulating hyperdiploid B cells have clonotypic immunoglobulin heavy chain rearrangements and may mediate spread of disease","volume":"6","author":"Pilarski L. M.","year":"2000","unstructured":"Pilarski L. M., Giannakopoulos N. V., Szczepek A., Masellis-Smith A., Mant M. J., Belch A. J. In multiple myeloma, circulating hyperdiploid B cells have clonotypic immunoglobulin heavy chain rearrangements and may mediate spread of disease. Clinical Cancer Research 2000; 6: 585\u2013596","journal-title":"Clinical Cancer Research"},{"key":"e_1_2_1_63_1","first-page":"4001","article-title":"Circulating CD19+ blood cell levels in myeloma","volume":"86","author":"Pilarski L. M","year":"1995","unstructured":"Pilarski L. M. Circulating CD19+ blood cell levels in myeloma. Blood 1995; 86: 4001","journal-title":"Blood"},{"key":"e_1_2_1_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1994.tb06732.x"},{"key":"e_1_2_1_65_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V84.10.3283.3283"},{"issue":"5","key":"e_1_2_1_66_1","first-page":"S41-S46","article-title":"A rationale for positive selection of peripheral blood stem cells in multiple myeloma: highly purified CD34+ cell fractions of leukapheresis products do not contain malignant cells","volume":"11","author":"Cremer F. W.","year":"1997","unstructured":"Cremer F. W., Kiel K., Sucker C., Wacker J., Atzberger A., Haas R., Goldschmidt H., Moos M. A rationale for positive selection of peripheral blood stem cells in multiple myeloma: highly purified CD34+ cell fractions of leukapheresis products do not contain malignant cells. Leukemia 1997; 11(5)S41-S46","journal-title":"Leukemia"},{"key":"e_1_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1700697"}],"container-title":["Leukemia &amp; Lymphoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/10428190109097764","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:54:52Z","timestamp":1770944092000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3109\/10428190109097764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":66,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["10.3109\/10428190109097764"],"URL":"https:\/\/doi.org\/10.3109\/10428190109097764","relation":{},"ISSN":["1042-8194","1029-2403"],"issn-type":[{"value":"1042-8194","type":"print"},{"value":"1029-2403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}