{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T03:58:42Z","timestamp":1792209522105,"version":"4.4.0"},"reference-count":42,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Leukemia & Lymphoma"],"published-print":{"date-parts":[[2015,6,3]]},"DOI":"10.3109\/10428194.2014.974040","type":"journal-article","created":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T08:53:00Z","timestamp":1412931180000},"page":"1763-1770","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":29,"title":["Efficacy, safety, pharmacokinetics and pharmacodynamics of SAR245409 (voxtalisib, XL765), an orally administered phosphoinositide 3-kinase\/mammalian target of rapamycin inhibitor: a phase 1 expansion cohort in patients with relapsed or refractory lymphoma"],"prefix":"10.1080","volume":"56","author":[{"given":"Kyriakos P.","family":"Papadopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coumaran","family":"Egile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Ruiz-Soto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiliang","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frauke","family":"Bentzien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drew","family":"Rasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pau","family":"Abrisqueta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie M.","family":"Vose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Tabernero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2014,11,19]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2013.780288"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-013-1770-9"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2010.08123.x"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404873"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1305656110"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-1543"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-3215"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3937"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.188"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.240"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-1060"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2010.154"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-13-250"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2867-13-48"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1254\/jphs.12149FP"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1314583"},{"issue":"1","key":"CIT0017","doi-asserted-by":"crossref","first-page":"8518","DOI":"10.1200\/jco.2013.31.15_suppl.8518","volume":"31","author":"Horwitz SM","year":"2013","journal-title":"J Clin Oncol"},{"issue":"1","key":"CIT0018","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1182\/blood.V122.21.87.87","volume":"122","author":"Dreyling M","year":"2013","journal-title":"Blood"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-11-537555"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-11-538546.There"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.20.7977"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.2813"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2010.226"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.053173"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-10-460832"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28206"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-2925"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-13-0709"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1200\/jco.2013.31.15_suppl.2012","volume":"31","author":"Cloughesy TF","year":"2013","journal-title":"J Clin Oncol"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noq193"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-12-0015"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-2403"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.2403"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1314608110"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds011"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.36.1360"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"3097","DOI":"10.1200\/jco.2012.30.15_suppl.3097","volume":"30","author":"Arkenau H-T","year":"2012","journal-title":"J Clin Oncol"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"3020","DOI":"10.1200\/jco.2011.29.15_suppl.3020","volume":"29","author":"Wagner AJ","year":"2011","journal-title":"J Clin Oncol"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-0714"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-13-0611"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1182\/blood.V116.21.1777.1777","volume":"116","author":"Kahl B","year":"2010","journal-title":"Blood"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1182\/blood.V122.21.86.86","volume":"122","author":"Brown JR","year":"2013","journal-title":"Blood"}],"container-title":["Leukemia & Lymphoma"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/10428194.2014.974040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T17:45:04Z","timestamp":1598377504000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/10428194.2014.974040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,19]]},"references-count":42,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,1,14]]},"published-print":{"date-parts":[[2015,6,3]]}},"alternative-id":["10.3109\/10428194.2014.974040"],"URL":"https:\/\/doi.org\/10.3109\/10428194.2014.974040","relation":{},"ISSN":["1042-8194","1029-2403"],"issn-type":[{"value":"1042-8194","type":"print"},{"value":"1029-2403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ilal20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ilal20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}