{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T11:24:44Z","timestamp":1770463484638,"version":"3.49.0"},"reference-count":103,"publisher":"Informa UK Limited","issue":"5-6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Leukemia &amp; Lymphoma"],"published-print":{"date-parts":[[1997,1]]},"DOI":"10.3109\/10428199709050880","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T20:33:26Z","timestamp":1455568406000},"page":"421-433","source":"Crossref","is-referenced-by-count":6,"title":["Transactivation of the Interleukin-1 Alpha Promoter by Human T-cell Leukemia Virus"],"prefix":"10.3109","volume":"26","author":[{"given":"Naoki","family":"Mori","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Prager","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/315641a0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/14.8.3167"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/14.20.7897"},{"key":"e_1_2_1_5_1","first-page":"77","article-title":"Interleukin-I gene (IL1) assigned to long arm of human chromosome 2","volume":"5","author":"Webb A. C.","year":"1986","unstructured":"Webb A. C., Collins K. L., Auron P. E., Eddy R. L., Nakai H., Byers M. G., Haley L. L., Henry W. M., Shows T. B. Interleukin-I gene (IL1) assigned to long arm of human chromosome 2. Lymphokine Rex 1986; 5: 77\u201385","journal-title":"Lymphokine Rex"},{"key":"e_1_2_1_6_1","first-page":"573","article-title":"Interleukin-1: A gene expression system regulated at multiple levels","volume":"5","author":"Auron P. E.","year":"1994","unstructured":"Auron P. E., Webb A. C. Interleukin-1: A gene expression system regulated at multiple levels. Eur. Cytokine New. 1994; 5: 573\u2013592","journal-title":"Eur. Cytokine New."},{"key":"e_1_2_1_7_1","first-page":"533","article-title":"Molecular studies on interleukin-1 a","volume":"5","author":"Furutani Y","year":"1994","unstructured":"Furutani Y. Molecular studies on interleukin-1 a. Eur. Cytokine Netw. 1994; 5: 533\u2013538","journal-title":"Eur. Cytokine Netw."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.15.7245"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.4.1204"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.14.5548"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1992.10.7.1141"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V78.6.1420.1420"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V83.12.3473.3473"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/306378a0"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.14.5235"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/317395a0"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(87)90437-5"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1986.tb04583.x"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.15.5389"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/16.14.6547"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V84.9.2904.2904"},{"key":"e_1_2_1_22_1","first-page":"3592","article-title":"Production of interleukin 8 in adult T-cell leukemia cells: Possible transactivation of the interleukin 8 gene by human T-cell leukemia virus type I tax","volume":"55","author":"Mori N.","year":"1995","unstructured":"Mori N., Murakami S., Oda S., Prager D., Eto S. Production of interleukin 8 in adult T-cell leukemia cells: Possible transactivation of the interleukin 8 gene by human T-cell leukemia virus type I tax. Cancer Res. 1995; 55: 3592\u20133597","journal-title":"Cancer Res."},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V88.3.1035.bloodjournal8831035"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.8.12.5581-5587.1988"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.22.8526"},{"key":"e_1_2_1_26_1","first-page":"1023","article-title":"HTLV-1 Tax induces expression of various immediate early serum responsive genes","volume":"6","author":"Fujii M.","year":"1991","unstructured":"Fujii M., Niki T., Mori T., Matsuda T., Matsui M., Nomura N., Seiki M. HTLV-1 Tax induces expression of various immediate early serum responsive genes. Oncogene 1991; 6: 1023\u20131029","journal-title":"Oncogene"},{"key":"e_1_2_1_27_1","first-page":"1851","article-title":"Transactivation of Krox-20","volume":"6","author":"Alexandre C.","year":"1991","unstructured":"Alexandre C., Charnay P., Verrier B. Transactivation of Krox-20. Krox-24 1991; 6: 1851\u20131857, promoters by the HTLV-I Tax protein through common regulatory elements. Oncogene","journal-title":"Krox-24"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/17.11.4101"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)41998-9"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.64.1.256-263.1990"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.172.3.759"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V81.4.1017.1017"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.11.9.4635-4641.1991"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.172.1.121"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.10.6191-6193.1992"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V81.1.95.95"},{"key":"e_1_2_1_37_1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1182\/blood.V84.1.350.350","article-title":"Human T-cell leukemia virus type I Tax induces intracel-Mar adhesion molecule-I expression in T cells","volume":"84","author":"Mori N.","year":"1994","unstructured":"Mori N., Murakami S., Oda S., Eto S. Human T-cell leukemia virus type I Tax induces intracel-Mar adhesion molecule-I expression in T cells. Blood 1994; 84: 350\u2013351","journal-title":"Blood"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.64.8.4002-4006.1990"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.62.12.4499-4509.1988"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/333776a0"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2497518"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.10.3.1281-1286.1990"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.6.11.2066"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)36557-2"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.67.10.6087-6095.1993"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2309119"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.48.28503"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.5.3280-3285.1996"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)31666-6"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.15.7070"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8211160"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.15.7303"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/22.15.3194"},{"key":"e_1_2_1_54_1","first-page":"779","article-title":"High levels of AP-Zbinding activity in cell lines infected with human T-cell leukemia virus type I: Possible enhancement of AP-2 binding by human T-cell leukemia virus type I tax","volume":"56","author":"Mod N.","year":"1996","unstructured":"Mod N., Prager D. High levels of AP-Zbinding activity in cell lines infected with human T-cell leukemia virus type I: Possible enhancement of AP-2 binding by human T-cell leukemia virus type I tax. Cancer Res. 1996; 56: 779\u2013782","journal-title":"Cancer Res."},{"key":"e_1_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/376606a0"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.7.4570-4575.1992"},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.4.1057"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1988.tb02840.x"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.24.8359"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1990.tb07639.x"},{"key":"e_1_2_1_61_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.12.7415"},{"key":"e_1_2_1_62_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.6.2031"},{"key":"e_1_2_1_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910350609"},{"key":"e_1_2_1_64_1","first-page":"893","article-title":"Epidemio-logical analysis of the distribution of antibody to adult T-cell leukemia-virus-associated antigen: Possible horizontal transmission of adult T-cell leukemia virus","volume":"73","author":"Tajima K.","year":"1982","unstructured":"Tajima K., Tominaga S., Suchi T., Kawagoe T., Komoda H., Hinuma Y., Oda T., Fujita K. Epidemio-logical analysis of the distribution of antibody to adult T-cell leukemia-virus-associated antigen: Possible horizontal transmission of adult T-cell leukemia virus. Jpn. J. Cancer Res. 1982; 73: 893\u2013901","journal-title":"Jpn. J. Cancer Res."},{"key":"e_1_2_1_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910430214"},{"key":"e_1_2_1_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/309640a0"},{"key":"e_1_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(88)90072-1"},{"key":"e_1_2_1_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)92734-5"},{"key":"e_1_2_1_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)91298-5"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)90038-X"},{"key":"e_1_2_1_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1992.tb00092.x"},{"key":"e_1_2_1_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91362-6"},{"key":"e_1_2_1_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92896-P"},{"key":"e_1_2_1_74_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6981847"},{"key":"e_1_2_1_75_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198608073150606"},{"key":"e_1_2_1_76_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113152"},{"key":"e_1_2_1_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1989.tb01672.x"},{"key":"e_1_2_1_78_1","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.4049\/jimmunol.138.10.3284","article-title":"Production of interleukin 1 by adult T cell leukemia (ATL) cell lines","volume":"138","author":"Yamashita U.","year":"1987","unstructured":"Yamashita U., Shirakawa F., Nakamura H. Production of interleukin 1 by adult T cell leukemia (ATL) cell lines. J. Immunol. 1987; 138: 3284\u20133289","journal-title":"J. Immunol."},{"key":"e_1_2_1_79_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.169.5.1853"},{"key":"e_1_2_1_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1995.tb01821.x"},{"key":"e_1_2_1_81_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.162.6.2169"},{"key":"e_1_2_1_82_1","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1182\/blood.V87.8.3410.bloodjournal8783410","article-title":"Transactivation of the interleukin-1 \u03b1 promoter by human T-cell leukemia virus type I and type II Tax proteins","volume":"87","author":"Mori N.","year":"1996","unstructured":"Mori N., Prager D. Transactivation of the interleukin-1 \u03b1 promoter by human T-cell leukemia virus type I and type II Tax proteins. Blood 1996; 87: 3410\u20133417","journal-title":"Blood"},{"key":"e_1_2_1_83_1","first-page":"275","article-title":"Activation of NF-k B by the HTLV-I trans-activator protein tax requires an additional factor present in lymphoid cells","volume":"1","author":"Ruben S. M.","year":"1989","unstructured":"Ruben S. M., Perkins A., Rosen C. A. Activation of NF-k B by the HTLV-I trans-activator protein tax requires an additional factor present in lymphoid cells. NewBiol. 1989; 1: 275","journal-title":"NewBiol."},{"key":"e_1_2_1_84_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198308043090501"},{"key":"e_1_2_1_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)92200-0"},{"key":"e_1_2_1_86_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.138.5.1464"},{"key":"e_1_2_1_87_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-124-5-2172"},{"key":"e_1_2_1_88_1","first-page":"4284","article-title":"Production of bone-resorbing activity corresponding to inter-leukin-1 \u03b1 by adult T-cell leukemia cells in humans","volume":"48","author":"Shirakawa F.","year":"1988","unstructured":"Shirakawa F., Yamashita U., Tanaka Y., Watanabe K., Sato K., Haratake J., Fujihira T., Oda S., Eto S. Production of bone-resorbing activity corresponding to inter-leukin-1 \u03b1 by adult T-cell leukemia cells in humans. Cancer Res. 1988; 48: 4284\u20134287","journal-title":"Cancer Res."},{"key":"e_1_2_1_89_1","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1182\/blood.V50.3.481.481","article-title":"Adult T-cell leukemia: Clinical and hematologic features of 16 cases","volume":"50","author":"Uchiyama T.","year":"1997","unstructured":"Uchiyama T., Yodoi J., Sagawa K., Takatsuki K., Uchino H. Adult T-cell leukemia: Clinical and hematologic features of 16 cases. Blood 1997; 50: 481\u2013492","journal-title":"Blood"},{"key":"e_1_2_1_90_1","first-page":"858","article-title":"Absolute neutrophilia in adult T cell leukemia","volume":"77","author":"Yamamoto S.","year":"1986","unstructured":"Yamamoto S., Hattori T., Asou N., Nishimura H., Kawano F., Yodoi J., Takatsuki K. Absolute neutrophilia in adult T cell leukemia. Jpn. J. Cancer Res. 1986; 77: 858\u2013861","journal-title":"Jpn. J. Cancer Res."},{"key":"e_1_2_1_91_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V87.6.2095.bloodjournal8762095"},{"key":"e_1_2_1_92_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1887217"},{"key":"e_1_2_1_93_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.155.3.1588"},{"key":"e_1_2_1_94_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117735"},{"key":"e_1_2_1_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(90)90068-K"},{"key":"e_1_2_1_96_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116862"},{"key":"e_1_2_1_97_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V75.12.2388.2388"},{"key":"e_1_2_1_98_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.153.10.4766"},{"key":"e_1_2_1_99_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V85.7.1865.bloodjournal8571865"},{"key":"e_1_2_1_100_1","first-page":"1732","article-title":"Transcriptional activator Tax of HTLV-I binds to the NF- k B precursor p105","volume":"7","author":"Hirai H.","year":"1992","unstructured":"Hirai H., Fujisawa J., Suzuki T., Ueda K., Muramatsu M., Tsuboi A., Arai N., Yoshida M. Transcriptional activator Tax of HTLV-I binds to the NF- k B precursor p105. Oncogene 1992; 7: 1732\u20131742","journal-title":"Oncogene"},{"key":"e_1_2_1_101_1","first-page":"2391","article-title":"A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF- k B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF- k B site and CArG box","volume":"8","author":"Suzuki T.","year":"1993","unstructured":"Suzuki T., Hirai H., Fujisawa J., Fujita T., Yoshida M. A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF- k B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF- k B site and CArG box. Oncogene 1993; 8: 2391\u20132397","journal-title":"Oncogene"},{"key":"e_1_2_1_102_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.9.3584"},{"key":"e_1_2_1_103_1","first-page":"1199","article-title":"Tax protein of HTLV-1 destabilizes the complexes of NF-k B and I k B-\u03b1 and induces nuclear translocation of NF- k B for transcriptional activation","volume":"10","author":"Suzuki T.","year":"1995","unstructured":"Suzuki T., Hirai H., Murakami T., Yoshida M. Tax protein of HTLV-1 destabilizes the complexes of NF-k B and I k B-\u03b1 and induces nuclear translocation of NF- k B for transcriptional activation. Oncogene 1995; 10: 1199\u20131207","journal-title":"Oncogene"},{"key":"e_1_2_1_104_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1299224"}],"container-title":["Leukemia &amp; Lymphoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/10428199709050880","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T16:37:25Z","timestamp":1770395845000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3109\/10428199709050880"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":103,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[1997,1]]}},"alternative-id":["10.3109\/10428199709050880"],"URL":"https:\/\/doi.org\/10.3109\/10428199709050880","relation":{},"ISSN":["1042-8194","1029-2403"],"issn-type":[{"value":"1042-8194","type":"print"},{"value":"1029-2403","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,1]]}}}