{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:02:30Z","timestamp":1790935350725,"version":"4.1.0"},"reference-count":49,"publisher":"Informa UK Limited","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Free Radical Research"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.3109\/10715762.2011.605361","type":"journal-article","created":{"date-parts":[[2011,7,14]],"date-time":"2011-07-14T14:12:30Z","timestamp":1310652750000},"page":"1173-1183","source":"Crossref","is-referenced-by-count":34,"title":["Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia\/reperfusion injury in diabetic rat heart"],"prefix":"10.1080","volume":"45","author":[{"given":"Toru","family":"Okazaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Otani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Shimazu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Yoshioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiji","family":"Iwasaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2011,8,10]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(89)90053-3"},{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s11892-009-0013-x","volume":"9","author":"Lago RM","year":"2009","journal-title":"Curr Diab Rep"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"778","DOI":"10.2337\/diabetes.54.3.778","volume":"54","author":"Liu X","year":"2005","journal-title":"Diabetes"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvp085"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2005.01.014"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1161\/ATVBAHA.107.160754","volume":"28","author":"Sasaki N","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200314172"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0968-0004(97)01147-X","volume":"22","author":"Mayer B","year":"1997","journal-title":"Trends Biochem Sci"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"14533","DOI":"10.1074\/jbc.R100011200","volume":"276","author":"Stuehr D","year":"2001","journal-title":"J Biol Chem"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1089\/ars.2009.2453","volume":"11","author":"Otani H","year":"2009","journal-title":"Antioxid Redox Signal"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000243924.00970.cb"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1093\/cvr\/cvn095","volume":"79","author":"Soliman H","year":"2008","journal-title":"Cardiovasc Res"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.yjmcc.2010.12.010","volume":"50","author":"Okazaki T","year":"2011","journal-title":"J Mol Cell Cardiol"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1042\/cs0960185"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"529","DOI":"10.18388\/abp.2002_3812","volume":"49","author":"Gumieniczek A","year":"2002","journal-title":"Acta Biochim Pol"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.lfs.2005.04.074","volume":"78","author":"Gumieniczek A","year":"2005","journal-title":"Life Sci"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/10715760500484336","volume":"40","author":"Xia Z","year":"2006","journal-title":"Free Radic Res"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.yjmcc.2004.07.008","volume":"37","author":"Fiordaliso F","year":"2004","journal-title":"J Mol Cell Cardiol"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"H81","DOI":"10.1152\/ajpheart.01140.2003","volume":"287","author":"Kido M","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1124\/jpet.301.2.543","volume":"301","author":"Gao F","year":"2002","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1139\/Y09-103","volume":"87","author":"Saini-Chohan HK","year":"2009","journal-title":"Can J Physiol Pharmacol"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01012.2001"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"H2051","DOI":"10.1152\/ajpheart.01102.2006","volume":"292","author":"Akita Y","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1253\/circj.CJ-08-0072","volume":"72","author":"Masano T","year":"2008","journal-title":"Circ J"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jchromb.2006.07.018","volume":"851","author":"Jobgen WS","year":"2007","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","volume":"126","author":"Green LC","year":"1982","journal-title":"Anal Biochem"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.2337\/db09-0267"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1161\/CIRCULATIONAHA.106.684795","volume":"116","author":"Xu J","year":"2007","journal-title":"Circulation"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.2011.05535.x"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1042\/bj3570593","volume":"357","author":"Alderton WK","year":"2001","journal-title":"Biochem J"},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0006-2952(95)00208-H","volume":"50","author":"Haramaki N","year":"1995","journal-title":"Biochem Pharmacol"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.vph.2006.04.001","volume":"45","author":"Sicard P","year":"2006","journal-title":"Vascul Pharmacol"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"95S","DOI":"10.1016\/0002-9343(91)90291-5","volume":"91","author":"Ferrari R","year":"1991","journal-title":"Am J Med"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1161\/01.RES.77.2.424","volume":"77","author":"Chen W","year":"1995","journal-title":"Circ Res"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s00395-006-0584-5","volume":"101","author":"Penna C","year":"2006","journal-title":"Basic Res Cardiol"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1089\/ars.2007.1679","volume":"10","author":"Otani H","year":"2008","journal-title":"Antioxid Redox Signal"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1146\/annurev.pharmtox.41.1.203","volume":"41","author":"Davis KL","year":"2001","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/abbi.1998.0755","volume":"356","author":"Ischiropoulos H","year":"1998","journal-title":"Arch Biochem Biophys"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"15021","DOI":"10.1074\/jbc.M112451200","volume":"277","author":"Balafanova Z","year":"2002","journal-title":"J Biol Chem"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"30945","DOI":"10.1074\/jbc.272.49.30945","volume":"272","author":"Gray MO","year":"1997","journal-title":"J Biol Chem"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.1999.1026"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2005.02.010"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1161\/01.ATV.0000217632.98717.a0","volume":"26","author":"Handy DE","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1038\/nrm1569","volume":"6","author":"Hess DT","year":"2005","journal-title":"Nat Rev Mol Cell Biol"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.cardiores.2004.01.013","volume":"62","author":"Martinez-Ruiz A","year":"2004","journal-title":"Cardiovasc Res"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1089\/ars.2006.8.1693","volume":"8","author":"Sun J","year":"2006","journal-title":"Antioxid Redox Signal"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.605519"},{"key":"CIT0048","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1161\/01.RES.0000202707.79018.0a","volume":"98","author":"Sun J","year":"2006","journal-title":"Circ Res"},{"key":"CIT0049","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1161\/CIRCRESAHA.109.209452","volume":"106","author":"Sun J","year":"2010","journal-title":"Circ Res"}],"container-title":["Free Radical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/10715762.2011.605361","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,21]],"date-time":"2020-06-21T09:06:13Z","timestamp":1592730373000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/10715762.2011.605361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,10]]},"references-count":49,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2011,7,15]]},"published-print":{"date-parts":[[2011,10]]}},"alternative-id":["10.3109\/10715762.2011.605361"],"URL":"https:\/\/doi.org\/10.3109\/10715762.2011.605361","relation":{},"ISSN":["1071-5762","1029-2470"],"issn-type":[{"value":"1071-5762","type":"print"},{"value":"1029-2470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8,10]]}}}