{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:57:51Z","timestamp":1777438671200,"version":"3.51.4"},"reference-count":48,"publisher":"Informa UK Limited","issue":"5","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Free Radical Research"],"published-print":{"date-parts":[[2016,5,3]]},"DOI":"10.3109\/10715762.2016.1149171","type":"journal-article","created":{"date-parts":[[2016,2,5]],"date-time":"2016-02-05T08:37:19Z","timestamp":1454661439000},"page":"514-522","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":7,"title":["Simvastatin prevents vascular complications in the chronic reactive oxygen species murine model of systemic sclerosis"],"prefix":"10.3109","volume":"50","author":[{"given":"Alessandra","family":"Bitto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Luca","family":"Bagnato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Pizzino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William Neal","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Irrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letteria","family":"Minutoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppina","family":"Russo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Squadrito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonino","family":"Saitta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Filippo","family":"Bagnato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenica","family":"Altavilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2016,3,17]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1002\/art.37988"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(75)90017-7"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-011-0219-1"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2006.12.006"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken307"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-73-2-317"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh478"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1186\/ar2986"},{"key":"CIT0009","first-page":"S76","volume":"30","author":"Zeng Y","year":"2012","journal-title":"Clin Exp Rheumatol"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.4081\/reumatismo.2012.360"},{"key":"CIT0011","first-page":"iii26","volume":"45","author":"Distler JH","year":"2006","journal-title":"Rheumatology (Oxford)"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200011)43:11<2437::AID-ANR10>3.0.CO;2-U"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1423.070"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1186\/ar4285"},{"key":"CIT0015","first-page":"1801","volume":"35","author":"Abou-Raya A","year":"2008","journal-title":"J Rheumatol"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1002\/art.21723"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket144"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0803705"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5446.1946"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1161\/hh1701.096614"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1080\/09629350400008794"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-857X(05)70295-7"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70014-K"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-008-0125-4"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1136\/ard.50.Suppl_4.866"},{"key":"CIT0026","first-page":"1325","volume":"20","author":"Blann AD","year":"1993","journal-title":"J Rheumatol"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2012.667566"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2014.12.006"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.03.204"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-011-1879-4"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1007\/s10517-007-0015-0"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2007.05.006"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2013.02.023"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1002\/art.37873"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1186\/ar4300"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.4103\/2045-8932.105028"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1097\/FJC.0b013e3180a72606"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-011-2183-5"},{"key":"CIT0039","first-page":"1323","volume":"35","author":"Del Papa N","year":"2008","journal-title":"J Rheumatol"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq003"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1002\/art.21899"},{"key":"CIT0042","author":"Huang J","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2007.05.013"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1002\/art.34354"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1186\/ar3445"},{"key":"CIT0046","first-page":"S-154","volume":"32","author":"Domsic RT","year":"2014","journal-title":"Clin Exp Rheumatol"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2014.03.014"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1186\/ar4267"}],"container-title":["Free Radical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/10715762.2016.1149171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,12,13]],"date-time":"2016-12-13T18:33:26Z","timestamp":1481654006000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/10715762.2016.1149171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,17]]},"references-count":48,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016,3,21]]},"published-print":{"date-parts":[[2016,5,3]]}},"alternative-id":["10.3109\/10715762.2016.1149171"],"URL":"https:\/\/doi.org\/10.3109\/10715762.2016.1149171","relation":{},"ISSN":["1071-5762","1029-2470"],"issn-type":[{"value":"1071-5762","type":"print"},{"value":"1029-2470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,17]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifra20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifra20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}