{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:59:04Z","timestamp":1787025544468,"version":"build-2736575974"},"reference-count":25,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceutical Biology"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.3109\/13880209.2011.626784","type":"journal-article","created":{"date-parts":[[2011,12,23]],"date-time":"2011-12-23T11:57:37Z","timestamp":1324641457000},"page":"25-29","source":"Crossref","is-referenced-by-count":14,"title":["Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma"],"prefix":"10.1080","volume":"50","author":[{"given":"John","family":"Opoku-Ansah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tannya R.","family":"Ibarra-Rivera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Pirrung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 S.","family":"Bachmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2011,12,23]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nrc1361","volume":"4","author":"Adams J","year":"2004","journal-title":"Nat Rev Cancer"},{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.bcp.2010.03.031","volume":"80","author":"Archer CR","year":"2010","journal-title":"Biochem Pharmacol"},{"key":"CIT0003","first-page":"247","volume":"67","author":"Bachmann AS","year":"2008","journal-title":"Hawaii Med J"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1002\/cbic.200900411","volume":"10","author":"Clerc J","year":"2009","journal-title":"Chembiochem"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"6507","DOI":"10.1073\/pnas.0901982106","volume":"106","author":"Clerc J","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"3991","DOI":"10.1002\/ejoc.201000317","volume":"21","author":"Clerc J","year":"2010","journal-title":"Eur J Org Chem"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1039\/C0CC02238A","volume":"47","author":"Clerc J","year":"2011","journal-title":"Chem Commun (Camb)"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1365-2184.2006.00402.x","volume":"39","author":"Coleman CS","year":"2006","journal-title":"Cell Prolif"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1021\/ol101252y","volume":"12","author":"Dai C","year":"2010","journal-title":"Org Lett"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0301-472X(03)00023-7","volume":"31","author":"Greenstein S","year":"2003","journal-title":"Exp Hematol"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/nature06782","volume":"452","author":"Groll M","year":"2008","journal-title":"Nature"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1128\/MMBR.64.3.624-653.2000","volume":"64","author":"Hirano SS","year":"2000","journal-title":"Microbiol Mol Biol Rev"},{"key":"CIT0013","author":"Ibarra-Rivera TR","year":"2011","journal-title":"Tetrahedron"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1182\/blood-2007-08-104950","volume":"112","author":"Oerlemans R","year":"2008","journal-title":"Blood"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.7164\/antibiotics.41.1331","volume":"41","author":"Oka M","year":"1988","journal-title":"J Antibiot"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.7164\/antibiotics.41.1812","volume":"41","author":"Oka M","year":"1988","journal-title":"J Antibiot"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.7164\/antibiotics.41.1906","volume":"41","author":"Oka M","year":"1988","journal-title":"J Antibiot"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.7164\/antibiotics.41.1338","volume":"41","author":"Oka M","year":"1988","journal-title":"J Antibiot"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-2218"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1021\/ol100761z","volume":"12","author":"Pirrung MC","year":"2010","journal-title":"Org Lett"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1038\/leu.2010.137","volume":"24","author":"Ri M","year":"2010","journal-title":"Leukemia"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"783","DOI":"10.7164\/antibiotics.43.783","volume":"43","author":"Shoji J","year":"1990","journal-title":"J Antibiot"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1073\/pnas.0405495102","volume":"102","author":"Slack A","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"788","DOI":"10.7164\/antibiotics.43.788","volume":"43","author":"Terui Y","year":"1990","journal-title":"J Antibiot"},{"key":"CIT0025","first-page":"6316","volume":"9","author":"Voorhees PM","year":"2003","journal-title":"Clin Cancer Res"}],"container-title":["Pharmaceutical Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/13880209.2011.626784","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T07:48:02Z","timestamp":1497944882000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/13880209.2011.626784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,23]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2011,10,21]]},"published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.3109\/13880209.2011.626784"],"URL":"https:\/\/doi.org\/10.3109\/13880209.2011.626784","relation":{},"ISSN":["1388-0209","1744-5116"],"issn-type":[{"value":"1388-0209","type":"print"},{"value":"1744-5116","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,23]]}}}