{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T15:08:11Z","timestamp":1773673691728,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["celltherapyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytotherapy"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.3109\/14653249.2012.663485","type":"journal-article","created":{"date-parts":[[2012,3,12]],"date-time":"2012-03-12T06:19:37Z","timestamp":1331533177000},"page":"630-638","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Therapeutic effects of human amniotic epithelial stem cells in Niemann\u2013Pick type C1 mice"],"prefix":"10.1016","volume":"14","author":[{"given":"Saet-Byul","family":"Hong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min-Soo","family":"Seo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-Bum","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoo-Jin","family":"Seo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong-Sung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung-Sun","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.3109\/14653249.2012.663485_bib0005","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1001\/jama.281.3.249","article-title":"Prevalence of lysosomal storage disorders","volume":"281","author":"Meikle","year":"1999","journal-title":"J American Medical Associ"},{"key":"10.3109\/14653249.2012.663485_bib0010","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1194\/jlr.M007211","article-title":"Recovery from liver disease in a Niemann\u2013Pick type C mouse model","volume":"51","author":"Sayre","year":"2010","journal-title":"J Lipid Res"},{"key":"10.3109\/14653249.2012.663485_bib0015","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1194\/jlr.P000331","article-title":"The national Niemann\u2013Pick type C1 disease database: correlation of lipid profiles, mutations, and biochemical phenotypes","volume":"51","author":"Garver","year":"2010","journal-title":"J Lipid Res"},{"key":"10.3109\/14653249.2012.663485_bib0020","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.3727\/096368910X545086","article-title":"Human umbilical cord blood-derived mesenchymal stem cells protect against neuronal cell death and ameliorate motor deficits in Niemann Pick type C1 mice","volume":"20","author":"Seo","year":"2011","journal-title":"Cell Transplant"},{"key":"10.3109\/14653249.2012.663485_bib0025","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.bbalip.2004.08.014","article-title":"The pathophysiology and mechanisms of NP-C disease","volume":"1685","author":"Sturley","year":"2004","journal-title":"Biochim Biophys Acta"},{"key":"10.3109\/14653249.2012.663485_bib0030","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s00441-010-0942-3","article-title":"Adipose tissue-derived stem cells rescue Purkinje neurons and alleviate inflammatory responses in Niemann\u2013Pick disease type C mice","volume":"340","author":"Bae","year":"2010","journal-title":"Cell Tissue Res"},{"key":"10.3109\/14653249.2012.663485_bib0035","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF03195222","article-title":"Neural stem cell implantation extends life in Niemann\u2013Pick C1 mice","volume":"48","author":"Ahmad","year":"2007","journal-title":"J Appl Genet"},{"key":"10.3109\/14653249.2012.663485_bib0040","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1155\/2008\/389815","article-title":"Stem cells in Niemann\u2013Pick disease","volume":"24","author":"Kim","year":"2008","journal-title":"Dis Markers"},{"key":"10.3109\/14653249.2012.663485_bib0045","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0022-3476(05)81695-6","article-title":"Niemann\u2013Pick disease type C: diagnosis and outcome in children, with particular reference to liver disease","volume":"123","author":"Kelly","year":"1993","journal-title":"J Pediatr"},{"key":"10.3109\/14653249.2012.663485_bib0050","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.3727\/096368910X504496","article-title":"Transplantation of human amnion epithelial cells reduces hepatic fibrosis in immunocompetent CCl-treated mice","volume":"19","author":"Manuelpillai","year":"2010","journal-title":"Cell Transplant"},{"key":"10.3109\/14653249.2012.663485_bib0055","doi-asserted-by":"crossref","first-page":"909","DOI":"10.3727\/096368910X543385","article-title":"Human amnion epithelial cells prevent bleomycin-induced lung injury and preserve lung function","volume":"20","author":"Murphy","year":"2011","journal-title":"Cell Transplant"},{"key":"10.3109\/14653249.2012.663485_bib0060","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.placenta.2008.09.009","article-title":"Human fetal membranes: a source of stem cells for tissue regeneration and repair?","volume":"30","author":"Ilancheran","year":"2009","journal-title":"Placenta"},{"key":"10.3109\/14653249.2012.663485_bib0065","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1634\/stemcells.2004-0357","article-title":"Stem cell characteristics of amniotic epithelial cells","volume":"23","author":"Miki","year":"2005","journal-title":"Stem Cells"},{"key":"10.3109\/14653249.2012.663485_bib0070","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1002\/hep.24255","article-title":"Hepatic differentiation of amniotic epithelial cells","volume":"53","author":"Marongiu","year":"2011","journal-title":"Hepatology"},{"key":"10.3109\/14653249.2012.663485_bib0075","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/S0140-6736(81)91212-5","article-title":"Immunogenicity of human amniotic epithelial cells after transplantation into volunteers","volume":"2","author":"Akle","year":"1981","journal-title":"Lancet"},{"key":"10.3109\/14653249.2012.663485_bib0080","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1002\/hep.20868","article-title":"Cholesterol accumulation and liver cell death in mice with Niemann\u2013Pick type C disease","volume":"42","author":"Beltroy","year":"2005","journal-title":"Hepatology"},{"key":"10.3109\/14653249.2012.663485_bib0085","first-page":"263","article-title":"Bone marrow osteogenic stem cells: in vitro cultivation and transplantation in diffusion chambers","volume":"20","author":"Friedenstein","year":"1987","journal-title":"Cell Tissue Kinet"},{"key":"10.3109\/14653249.2012.663485_bib0090","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s12015-008-9010-8","article-title":"Sources of stem cells for regenerative medicine","volume":"4","author":"Hipp","year":"2008","journal-title":"Stem Cell Rev"},{"key":"10.3109\/14653249.2012.663485_bib0095","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.3727\/096368909X471288","article-title":"Protocols for hematopoietic stem cell expansion from umbilical cord blood","volume":"18","author":"Koestenbauer","year":"2009","journal-title":"Cell Transplant"},{"key":"10.3109\/14653249.2012.663485_bib0100","first-page":"441","article-title":"Isolation and characterization of stem cells from the placenta and the umbilical cord","volume":"49","author":"Mihu","year":"2008","journal-title":"Rom J Morphol Embryol"},{"key":"10.3109\/14653249.2012.663485_bib0105","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1634\/stemcells.2007-0594","article-title":"Concise review. Isolation and characterization of cells from human term placenta: outcome of the first international workshop on placenta derived stem cells","volume":"26","author":"Parolini","year":"2008","journal-title":"Stem Cells"},{"key":"10.3109\/14653249.2012.663485_bib0110","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1749-0774.2010.00096.x","article-title":"Value of human amniotic epithelial cells in tissue engineering for cornea","volume":"23","author":"Fatimah","year":"2010","journal-title":"Hum Cell"},{"key":"10.3109\/14653249.2012.663485_bib0115","doi-asserted-by":"crossref","first-page":"G300","DOI":"10.1152\/ajpgi.00568.2004","article-title":"Liver disease with altered bile acid transport in Niemann\u2013Pick C mice on a high-fat, 1% cholesterol diet","volume":"289","author":"Erickson","year":"2005","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.3109\/14653249.2012.663485_bib0120","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/stem.401","article-title":"Bone marrow-derived mesenchymal stem cells prevent the loss of Niemann\u2013Pick type C mouse Purkinje neurons by correcting sphingolipid metabolism and increasing sphingosine-1-phosphate","volume":"28","author":"Lee","year":"2010","journal-title":"Stem Cells"},{"key":"10.3109\/14653249.2012.663485_bib0125","doi-asserted-by":"crossref","first-page":"14470","DOI":"10.1523\/JNEUROSCI.4823-07.2007","article-title":"Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse","volume":"27","author":"Repa","year":"2007","journal-title":"J Neurosci"}],"container-title":["Cytotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1465324912706758?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1465324912706758?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T22:16:10Z","timestamp":1761430570000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1465324912706758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["S1465324912706758"],"URL":"https:\/\/doi.org\/10.3109\/14653249.2012.663485","relation":{},"ISSN":["1465-3249"],"issn-type":[{"value":"1465-3249","type":"print"}],"subject":[],"published":{"date-parts":[[2012,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic effects of human amniotic epithelial stem cells in Niemann\u2013Pick type C1 mice","name":"articletitle","label":"Article Title"},{"value":"Cytotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3109\/14653249.2012.663485","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}