{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:39:00Z","timestamp":1791322740321,"version":"4.3.1"},"reference-count":47,"publisher":"Informa UK Limited","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"published-print":{"date-parts":[[2013,4,1]]},"DOI":"10.3109\/14756366.2012.720573","type":"journal-article","created":{"date-parts":[[2012,9,27]],"date-time":"2012-09-27T18:26:58Z","timestamp":1348770418000},"page":"343-349","source":"Crossref","is-referenced-by-count":27,"title":["Synthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms"],"prefix":"10.1080","volume":"28","author":[{"given":"Fatma","family":"Allouche","sequence":"first","affiliation":[{"name":"Laboratoire de Chimie Appliqu\u00e9e: H\u00e9t\u00e9rocycles, Corps Gras et Polym\u00e8res Facult\u00e9 des Sciences de Sfax, 3018 Sfax, Tunisie"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fakher","family":"Chabchoub","sequence":"additional","affiliation":[{"name":"Laboratoire de Chimie Appliqu\u00e9e: H\u00e9t\u00e9rocycles, Corps Gras et Polym\u00e8res Facult\u00e9 des Sciences de Sfax, 3018 Sfax, Tunisie"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Carta","sequence":"additional","affiliation":[{"name":"University of Florence, dipartimento di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[{"name":"University of Florence, dipartimento di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2012,9,27]]},"reference":[{"key":"CIT0001","unstructured":"Zhu J, Bienayme H. Multicomponent Reactions. Wiley-VCH, Verlag GmbH & Co.KgaA: Weinheim, 2005: 311\u2013341."},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.2174\/0929867033368600"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1039\/B406545J","volume":"2","author":"Yamada T","year":"2004","journal-title":"Org Biomol Chem"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.5570270262"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1021\/jm00146a007"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1080\/00397911.2010.486516"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2007.06.002"},{"key":"CIT0008","first-page":"179","volume":"7","author":"Ranjana A","year":"2011","journal-title":"J Org Chem"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2008.06.054"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1016\/j.bmc.2011.01.058","volume":"19","author":"Kunal N","year":"2011","journal-title":"Bioorg Med Chem"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"5775","DOI":"10.1016\/j.bmc.2007.06.004","volume":"15","author":"Nesrin GK","year":"2007","journal-title":"Bioorg Med Chem"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2007.07.034"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2008.01.034"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2007.11.054"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2008.06.054"},{"key":"CIT0016","first-page":"33","volume":"46","author":"Guerrera F","year":"1991","journal-title":"Farmaco"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.3390\/71000756"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.5570430435"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2008.07.017"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1016\/S0968-0896(03)00145-7","volume":"11","author":"Diana P","year":"2003","journal-title":"Bioorg Med Chem"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/j.tetlet.2011.01.040","volume":"52","author":"Colomer JP","year":"2011","journal-title":"Tetrahedron Lett"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2008.07.017"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"3544","DOI":"10.1021\/jm0600390","volume":"49","author":"Domarkas J","year":"2006","journal-title":"J Med Chem"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1016\/j.tetlet.2007.05.136","volume":"48","author":"Hess S","year":"2007","journal-title":"Tetrahedron Lett"},{"key":"CIT0025","first-page":"151","volume":"16","author":"Davoodnia A","year":"2006","journal-title":"Indian J Heterocylic Chem"},{"key":"CIT0026","unstructured":"Cheng CC, Rolande KR. Potential purine antagonists. VI. Synthesis of-1-alkyl and-1-aryl-4-substituted pyrazolo[3, 4-d]pyrimidines 1956; 21: 1240\u20131256."},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"4605","DOI":"10.1021\/jo00172a033","volume":"48","author":"Press JB","year":"1983","journal-title":"J Org Chem"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2467"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3554"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.05.009"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1080\/14756360410001689540"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.11.69"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2011.00034"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1002\/med.10025"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"7057","DOI":"10.1002\/chem.200600159","volume":"12","author":"Temperini C","year":"2006","journal-title":"Chemistry"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1021\/jm1003667"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1021\/ja809683v"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1021\/jm901287j"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1021\/jm200983e"},{"key":"CIT0040","author":"Alp C","year":"2012","journal-title":"J Enzyme Inhib Med Chem"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0021-9258(18)62326-9","volume":"246","author":"Khalifah RJ","year":"1971","journal-title":"J Biol Chem"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2011.597749"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"863","DOI":"10.3109\/14756360903571685","volume":"25","author":"Baranauskiene L","year":"2010","journal-title":"J Enzyme Inhib Med Chem"},{"key":"CIT0044","author":"Maresca A","year":"2012","journal-title":"J Enzyme Inhib Med Chem"},{"key":"CIT0045","author":"Maresca A","year":"2012","journal-title":"J Enzyme Inhib Med Chem"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1021\/cr200176r"},{"key":"CIT0047","doi-asserted-by":"crossref","first-page":"7047","DOI":"10.1016\/S0040-4039(00)01130-8","volume":"41","author":"Okada M","year":"2000","journal-title":"Tetrahedron Lett"}],"container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/14756366.2012.720573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T17:54:31Z","timestamp":1643478871000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3109\/14756366.2012.720573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,27]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,4,1]]}},"alternative-id":["10.3109\/14756366.2012.720573"],"URL":"https:\/\/doi.org\/10.3109\/14756366.2012.720573","relation":{},"ISSN":["1475-6366","1475-6374"],"issn-type":[{"value":"1475-6366","type":"print"},{"value":"1475-6374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,27]]}}}