{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T15:23:00Z","timestamp":1772810580914,"version":"3.50.1"},"reference-count":108,"publisher":"Informa UK Limited","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"DOI":"10.3109\/14756366.2015.1036051","type":"journal-article","created":{"date-parts":[[2015,4,20]],"date-time":"2015-04-20T14:34:29Z","timestamp":1429540469000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":32,"title":["Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin"],"prefix":"10.3109","author":[{"given":"Hulya","family":"Gocer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fevzi","family":"Topal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meryem","family":"Topal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"K\u00fc\u00e7\u00fck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilek","family":"Teke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130lhami","family":"G\u00fcl\u00e7in","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saleh H.","family":"Alwasel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2015,4,20]]},"reference":[{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-011-0774-2"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.molstruc.2014.03.010","volume":"1067","author":"Makarova K","year":"2014","journal-title":"J Mol Struct"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1080\/14756360601164903"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2008.05.003"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-079X.2002.20920.x"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-079X.2003.00042.x"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.27.613"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2003.07.012"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2005.05.006"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1007\/s00217-006-0265-5"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.3109\/09637486.2011.585963"},{"key":"CIT0013","first-page":"1283","volume":"17","author":"G\u00fcl\u00e7in \u0130","year":"2008","journal-title":"Fresen Environ Bull"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1007\/s00226-008-0234-1"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.2174\/092986609787049394"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2005.09.011"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2005.05.103"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.3109\/14756360903425239"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-006-0379-x"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1080\/14756360701626223"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1080\/10942912.2010.511924"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2008.09.023"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/j.ifset.2009.07.002"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2010.0197"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1039\/b300099k"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2012.03.035"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297909030092"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s11373-005-9031-0","volume":"13","author":"Wang YH","year":"2006","journal-title":"J Biomed Sci"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.61.651"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.11.013"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-012-9497-4"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0031-6997(24)01472-8","volume":"52","author":"Middleton E","year":"2000","journal-title":"Pharmacol Rev"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.2174\/138920006778520570"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.3945\/an.110.000026"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.3109\/00498254.2012.670737"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2007.04.020"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ejmech.2013.10.081","volume":"71","author":"Zolnowska B","year":"2014","journal-title":"Eur J Med Chem"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2013.03.077"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201300273"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1080\/14756360310001656736"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.30.2257"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2467"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2012.750311"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201400257"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2012.763163"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201300349"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.10.5.575"},{"key":"CIT0048","doi-asserted-by":"crossref","unstructured":"Mincione F, Scozzafava A, Supuran CT. In drug design of zinc-enzyme inhibitors: functional, structural, and disease applications. Hoboken: Wiley; 2009:139","DOI":"10.1002\/9780470508169.ch5"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.05.009"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.04.007"},{"key":"CIT0051","first-page":"408","volume":"13","author":"G\u00fcl\u00e7in I","year":"2013","journal-title":"Mini Rev Med Chem"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2012.670807"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.2174\/138161208783877820"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2014.07.009"},{"key":"CIT0055","doi-asserted-by":"crossref","unstructured":"Scozzafava A, Passaponti M, Supuran CT, G\u00fcl\u00e7in \u0130, Carbonic anhydrase inhibitors: guaiacol and catechol derivatives effectively inhibit certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII). J Enzyme Inhib Med Chem 2015; DOI:10.3109\/14756366.2014.956310","DOI":"10.3109\/14756366.2014.956310"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.01.031"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1021\/jm501573b"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-894X(03)00581-X"},{"key":"CIT0059","doi-asserted-by":"crossref","unstructured":"Taslimi P, Gulcin \u0130, Ozgeris B, et al. The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives. J Enzyme Inhib Med Chem 2015; DOI:10.3109\/14756366.2015.1014476","DOI":"10.3109\/14756366.2015.1014476"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201300228"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1002\/etc.5620200104"},{"key":"CIT0063","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.mehy.2007.03.032","volume":"69","author":"Allam AR","year":"2007","journal-title":"Med Hypotheses"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1385\/JMN:20:3:369"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.03.006"},{"key":"CIT0066","first-page":"403","volume":"54","author":"Hobbiger F","year":"1961","journal-title":"Proc R Soc Med"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(93)90040-Y"},{"key":"CIT0068","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.foodchem.2011.11.093","volume":"132","author":"Ryu HW","year":"2012","journal-title":"Food Chem"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2478\/v10222-012-0089-x","volume":"64","author":"Szwajgier D","year":"2014","journal-title":"Pol J Food Nutr Sci"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1021\/jf9029332"},{"key":"CIT0071","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.lfs.2013.11.014","volume":"96","author":"Gutierres JM","year":"2013","journal-title":"Life Sci"},{"key":"CIT0072","doi-asserted-by":"crossref","first-page":"9403","DOI":"10.3390\/molecules19079403","volume":"19","author":"Pervin M","year":"2014","journal-title":"Molecules"},{"key":"CIT0073","doi-asserted-by":"crossref","first-page":"9999","DOI":"10.3390\/molecules19079999","volume":"19","author":"Zhang DB","year":"2014","journal-title":"Molecules"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1556\/AVet.52.2004.4.4"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1080\/14756360701474780"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2011.01104.x"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2012.08.072"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1080\/1475636032000141890"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1080\/09712119.2005.9706791"},{"key":"CIT0081","first-page":"841","volume":"29","author":"Hisar O","year":"2005","journal-title":"Turk J Vet Anim Sci"},{"key":"CIT0082","doi-asserted-by":"crossref","first-page":"4221","DOI":"10.1016\/S0021-9258(18)95800-X","volume":"242","author":"Verpoorte JA","year":"1967","journal-title":"J Biol Chem"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2009.07.019"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.7813\/2075-4124.2013\/5-4\/A.21"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.2174\/092986608784246506"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.31.2036"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1021\/ja01318a036"},{"key":"CIT0089","doi-asserted-by":"crossref","unstructured":"Y\u0131ld\u0131r\u0131m A, Atmaca U, Keskin A, et al. N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II. Bioorg Med Chem 2015; DOI:10.1016\/j.bmc.2014.12.054","DOI":"10.1016\/j.bmc.2014.12.054"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201100272"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201300054"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.05.071"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(61)90145-9"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.3906\/kim-1403-5"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.07.038"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2010.01.076"},{"key":"CIT0097","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/j.bmcl.2008.01.077","volume":"18","author":"Innocenti A","year":"2008","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2010.00965.x"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.3390\/molecules18022328"},{"key":"CIT0100","doi-asserted-by":"crossref","first-page":"3659","DOI":"10.1021\/ja00087a086","volume":"116","author":"Nair SK","year":"1994","journal-title":"J Am Chem Soc"},{"key":"CIT0101","doi-asserted-by":"crossref","first-page":"7424","DOI":"10.1016\/j.bmc.2008.06.013","volume":"16","author":"Innocenti A","year":"2008","journal-title":"Bioorg Med Chem"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2009.11.021"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1080\/1475636040001704461"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2012.715287"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2013.01.019"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0702899104"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1021\/bi9007512"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.3109\/14756360903514164"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.3390\/molecules190710103"},{"key":"CIT0110","doi-asserted-by":"crossref","unstructured":"Scozzafava A, Kal\u0131n P, Supuran CT, et al. The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX and XII). J Enzyme Inhib Med Chem 2015; DOI: 10.3109\/14756366.2014.999236","DOI":"10.3109\/14756366.2014.999236"}],"container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/14756366.2015.1036051","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T19:23:51Z","timestamp":1747941831000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/14756366.2015.1036051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,20]]},"references-count":108,"alternative-id":["10.3109\/14756366.2015.1036051"],"URL":"https:\/\/doi.org\/10.3109\/14756366.2015.1036051","relation":{},"ISSN":["1475-6366","1475-6374"],"issn-type":[{"value":"1475-6366","type":"print"},{"value":"1475-6374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,20]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ienz20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ienz20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}