{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T23:55:49Z","timestamp":1787270149342,"version":"build-2736575974"},"reference-count":44,"publisher":"Informa UK Limited","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Maternal-Fetal & Neonatal Medicine"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.3109\/14767058.2012.733766","type":"journal-article","created":{"date-parts":[[2012,10,4]],"date-time":"2012-10-04T09:10:43Z","timestamp":1349341843000},"page":"491-496","source":"Crossref","is-referenced-by-count":78,"title":["The severity of hypoxic changes and oxidative DNA damage in the placenta of early-onset preeclamptic women and fetal growth restriction"],"prefix":"10.1080","volume":"26","author":[{"given":"Chiharu","family":"Kimura","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazushi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Iwasaki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshitaka","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Shinohara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Wakatsuki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2012,11,8]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)01223-0"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90665-0"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90778-3"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2009.222"},{"key":"e_1_3_2_6_1","first-page":"3225","article-title":"Augmented placental production of leptin in preeclampsia: possible involvement of placental hypoxia.","volume":"83","author":"Mise H","year":"1998","unstructured":"Mise H, Sagawa N, Matsumoto T, Yura S, Nanno H, Itoh H, Mori T, et al. Augmented placental production of leptin in preeclampsia: possible involvement of placental hypoxia. J Clin Endocrinol Metab 1998;83:3225\u20133229.","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.1310070206"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.294.6579.1051"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-999316"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2011.02.004"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2006.01.008"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1081\/PRG-100100138"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.07.049"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17987-2"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1081\/PRG-120021060"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.107607"},{"key":"e_1_3_2_17_1","first-page":"37","article-title":"Performance and clinical application of a new, fast method for the detection of hydroperoxides in serum","volume":"44","author":"Trotti R","year":"2002","unstructured":"Trotti R, Carratelli M, Barbieri M. Performance and clinical application of a new, fast method for the detection of hydroperoxides in serum. Panminerva Med 2002:44:37\u201340.","journal-title":"Panminerva Med"},{"key":"e_1_3_2_18_1","first-page":"59","article-title":"Normal values of reactive oxygen metabolites on the cord-blood of full-term infants with a colorimetric method.","volume":"71","author":"Parmigiani S","year":"2000","unstructured":"Parmigiani S, Payer C, Massari A, Bussolati G, Bevilacqua G. Normal values of reactive oxygen metabolites on the cord-blood of full-term infants with a colorimetric method. Acta Biomed Ateneo Parmense 2000;71:59\u201364.","journal-title":"Acta Biomed Ateneo Parmense"},{"key":"e_1_3_2_19_1","first-page":"127","article-title":"A simple test to monitor oxidative stress","volume":"18","author":"Cesarone MR","year":"1998","unstructured":"Cesarone MR, Belcaro G, Carratelli M, Cornelli U, De Sanctis MT, Incandela I, Barsotti A, et al. A simple test to monitor oxidative stress. Int Angiol 1998:18:127\u2013130.","journal-title":"Int Angiol"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/10715768909087933"},{"key":"e_1_3_2_21_1","first-page":"99","volume-title":"Oxidative Stress: Oxidants and Antioxidants","author":"Kasai H","year":"1991","unstructured":"Kasai H, Nishimura S. Formation of 8-hydroxydeoxy-guanosine in DNA by oxygen radicals and its biological significance. In: Sies H, editor. Oxidative Stress: Oxidants and Antioxidants. London: Academic Press Ltd.; 1991. pp 99\u2013116."},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0921-8777(90)90004-O"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1992.tb05097.x"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(94)34086-2"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.24.11450"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.20.5519"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.5.1087"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/360741a0"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.12.12.5447-5454.1992"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod63.2.559"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI8316"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2004.02.011"},{"key":"e_1_3_2_33_1","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1053\/plac.2002.0815","article-title":"Adriana and Luisa Castellucci Award Lecture 2001. Hypoxia inducible factor-1: oxygen regulation of trophoblast differentiation in normal and pre-eclamptic pregnancies-a review","volume":"23","author":"Caniggia I","year":"2002","unstructured":"Caniggia I, Winter JL. Adriana and Luisa Castellucci Award Lecture 2001. Hypoxia inducible factor-1: oxygen regulation of trophoblast differentiation in normal and pre-eclamptic pregnancies-a review. Placenta. 2002;23 (Suppl A):S47\u2013S57.","journal-title":"Placenta"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1550"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2008.03.006"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa055352"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031884"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20060161"},{"key":"e_1_3_2_39_1","doi-asserted-by":"crossref","first-page":"175 e171","DOI":"10.1016\/j.ajog.2007.08.052","article-title":"Circulatory soluble endoglin and its predictive value for preeclampsia in second-trimester pregnancies with abnormal uterine perfusion","volume":"198","author":"Stepan H","year":"2008","unstructured":"Stepan H, Geipel A, Schwarz F, Kramer T, Wessel N, Faber R. Circulatory soluble endoglin and its predictive value for preeclampsia in second-trimester pregnancies with abnormal uterine perfusion. Am J Obstet Gynecol 2008:198:175 e171\u2013176.","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050701830480"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1042"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2008.070640"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00794.2005"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M207160200"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/275613"}],"container-title":["The Journal of Maternal-Fetal & Neonatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/14767058.2012.733766","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T21:52:50Z","timestamp":1770933170000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3109\/14767058.2012.733766"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,8]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.3109\/14767058.2012.733766"],"URL":"https:\/\/doi.org\/10.3109\/14767058.2012.733766","relation":{},"ISSN":["1476-7058","1476-4954"],"issn-type":[{"value":"1476-7058","type":"print"},{"value":"1476-4954","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,8]]}}}