{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T06:40:46Z","timestamp":1769150446630,"version":"3.49.0"},"reference-count":39,"publisher":"Informa UK Limited","issue":"9","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Toxicology Mechanisms and Methods"],"published-print":{"date-parts":[[2015,11,22]]},"DOI":"10.3109\/15376516.2015.1077361","type":"journal-article","created":{"date-parts":[[2015,11,16]],"date-time":"2015-11-16T07:06:26Z","timestamp":1447657586000},"page":"708-717","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":14,"title":["Mechanism of protective effect of phyllanthin against carbon tetrachloride-induced hepatotoxicity and experimental liver fibrosis in mice"],"prefix":"10.3109","volume":"25","author":[{"given":"Rajesh","family":"Krithika","sequence":"first","affiliation":[{"name":"Department of Zoology, University School of Sciences, Gujarat University, Ahmedabad, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasavan","family":"Jyothilakshmi","sequence":"additional","affiliation":[{"name":"Department of Medical Biochemistry, Dr. A.L.M.Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai, India, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karunakar","family":"Prashantha","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, PES Institute of Technology, BSK III Stage, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramtej J.","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Zoology, University School of Sciences, Gujarat University, Ahmedabad, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2015,8,31]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.3923\/jbs.2006.457.468"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1126\/science.1071809"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1515\/znc-2001-7-826"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2007.01.008"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1042\/bj20020894"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2010.01.003"},{"key":"CIT0007","first-page":"237","volume":"117","author":"Constandinou C","year":"2005","journal-title":"Methods Mol Med"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0706172"},{"key":"CIT0009","volume-title":"The PyMOL molecular graphics system","author":"DeLano WL","year":"2002"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1021\/jm0400247"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1177\/153537020222700502","volume":"227","author":"Ghosh AK","year":"2002","journal-title":"Exp Biol Med"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80555-3"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.088690"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfh120"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1177\/0748233714532996"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2009.06.014"},{"key":"CIT0017","first-page":"439","volume":"66","author":"Krithika R","year":"2009","journal-title":"Acta Pol Pharm Drug Res"},{"key":"CIT0018","first-page":"579","volume":"66","author":"Krithika R","year":"2009","journal-title":"Acta Pol Pharm Drug Res"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"S64","DOI":"10.1016\/S2222-1808(14)60416-3","volume":"4","author":"Krithika R","year":"2013","journal-title":"Asia Pac J Trop Dis"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/S0973-6883(11)60123-0"},{"key":"CIT0021","doi-asserted-by":"crossref","unstructured":"Laping NJ, Huet S. (2006). TGF-\u03b2 receptor kinase inhibitors for treatment of fibrosis. In: Dijke P, Haldin CH, eds. Smad signal transduction: Smads in proliferation, differentiation and disease. Vol. 5. Berlin, Germany: Springer Verlag, 443\u201359","DOI":"10.1007\/1-4020-4709-6_22"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1007\/s12079-008-0029-z"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2005.01192.x"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840110412"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-987X(19981115)19:14<1639::AID-JCC10>3.0.CO;2-B"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.05.183"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.7.2572"},{"key":"CIT0028","first-page":"57","volume":"17","author":"Sanner MF","year":"1999","journal-title":"J Mol Graphics Mod"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00432-X"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i15.2269"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/0378-8741(85)90026-1"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1002\/pca.936"},{"key":"CIT0033","first-page":"309","volume":"65","author":"Venkatesan P","year":"2003","journal-title":"Indian J Pharm Sci"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2004.02.007"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/8.2.127"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2010007500132"},{"key":"CIT0037","first-page":"235","volume-title":"The methodology of connective tissue research","author":"Woessner JF","year":"1976"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1021\/cen-v087n045.p048"},{"key":"CIT0039","first-page":"915","volume":"25","author":"Yao HW","year":"2004","journal-title":"Acta Pharmacol Sin"}],"container-title":["Toxicology Mechanisms and Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/15376516.2015.1077361","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T23:29:37Z","timestamp":1598743777000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3109\/15376516.2015.1077361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,31]]},"references-count":39,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,11,22]]}},"alternative-id":["10.3109\/15376516.2015.1077361"],"URL":"https:\/\/doi.org\/10.3109\/15376516.2015.1077361","relation":{},"ISSN":["1537-6516","1537-6524"],"issn-type":[{"value":"1537-6516","type":"print"},{"value":"1537-6524","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,31]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=itxm20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=itxm20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2015-05-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-07-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-08-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}