{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:55:30Z","timestamp":1791366930700,"version":"4.3.1"},"reference-count":66,"publisher":"MJS Publishing, Medical Journals Sweden AB","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Oncologica"],"published-print":{"date-parts":[[1991,1]]},"DOI":"10.3109\/02841869109092438","type":"journal-article","created":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T09:15:10Z","timestamp":1373015710000},"page":"668-675","source":"Crossref","is-referenced-by-count":66,"title":["7th Jan Waldenstr\u00f6m Lecture. The Biology of Human Cancer Metastasis"],"prefix":"10.2340","volume":"30","author":[{"given":"Isaiah J.","family":"Fidler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2013,7,5]]},"reference":[{"issue":"137","key":"CIT0001","first-page":"209","volume":"24","author":"Fidler I J, Balch CM.","year":"1987","journal-title":"Cuff Probi Surg"},{"key":"CIT0002","first-page":"6130","volume":"50","author":"Fidler U","year":"1990","journal-title":"H.A. Clowes Memorial Award Lecture. Cancer Res"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1126\/science.7112116","volume":"217","author":"Fidler U","year":"1982","journal-title":"Science"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/BF00047691","volume":"3","author":"Nicolson GL","year":"1984","journal-title":"Cancer Metastasis Rev"},{"key":"CIT0005","first-page":"2259","volume":"44","author":"Heppner G","year":"1984","journal-title":"Cancer Res"},{"key":"CIT0006","first-page":"207","volume":"12","author":"Fidler U","year":"1985","journal-title":"Semin Oncol"},{"key":"CIT0007","first-page":"183","volume":"70","author":"Poste G","year":"1986","journal-title":"Cancer Treat Rep"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/283139a0","volume":"283","author":"Poste G","year":"1979","journal-title":"Nature"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1126\/science.2432664","volume":"235","author":"Folkman J","year":"1987","journal-title":"Science"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-230X(08)60034-2","volume":"46","author":"Liotta LA","year":"1986","journal-title":"Cancer Res"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF00048970","volume":"2","author":"Mareei M","year":"1983","journal-title":"Cancer Metastasis Rev"},{"key":"CIT0014","first-page":"791","volume":"122","author":"Fisher B","year":"1966","journal-title":"Surg Gynecol Obstet"},{"key":"CIT0015","first-page":"773","volume":"45","author":"Fidler IJ","year":"1970","journal-title":"J Nail Cancer Inst"},{"key":"CIT0016","first-page":"175","volume":"948","author":"Nicolson GL","year":"1988","journal-title":"Biochem Biophys Acta"},{"key":"CIT0017","first-page":"1","volume":"3","author":"Weiss L","year":"1986","journal-title":"Cancer Rev"},{"key":"CIT0018","first-page":"4714","volume":"45","author":"Fidler U","year":"1985","journal-title":"Cancer Res"},{"key":"CIT0019","first-page":"593","volume":"27","author":"Talmadge JE","year":"1978","journal-title":"Nature"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/newbio242148a0","volume":"242","author":"Fidler U","year":"1973","journal-title":"Nature (New Biol)"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/BF00048224","volume":"1","author":"Poste G","year":"1982","journal-title":"Cancer Metastasis Rev"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1126\/science.887927","volume":"197","author":"Fidler U","year":"1977","journal-title":"Science"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1093\/genetics\/28.6.491","volume":"28","author":"Luria SE","year":"1943","journal-title":"Genetics"},{"key":"CIT0024","first-page":"541","volume":"63","author":"Kripke ML","year":"1979","journal-title":"Speculation on the role of ultraviolet radiation in the development of malignant melanoma J Natl Cancer Inst"},{"key":"CIT0025","first-page":"947","volume":"67","author":"Fidler U","year":"1981","journal-title":"Demon-stration of multiple phenotype diversity in a murine melanoma of recent origin. J Natl Cancer Inst"},{"key":"CIT0026","first-page":"975","volume":"69","author":"Talmadge JE","year":"1982","journal-title":"J Natl Cancer Inst"},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/BF00049529","volume":"5","author":"Fidler U","year":"1986","journal-title":"Cancer Metastasis Rev"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0140-6736(00)49915-0","volume":"1","author":"Paget S","year":"1889","journal-title":"Lancet"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/BF00049477","volume":"1","author":"Hart IR","year":"1982","journal-title":"Cancer Metastasis Rev"},{"key":"CIT0030","first-page":"3584","volume":"44","author":"Tarn D","year":"1984","journal-title":"Cancer Res"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/ijc.2910410419","volume":"41","author":"Schackert G","year":"1988","journal-title":"Int J Cancer"},{"issue":"347","key":"CIT0033","first-page":"8","volume":"48","author":"Schackert G","year":"1988","journal-title":"Cancer Res"},{"key":"CIT0034","first-page":"303","volume":"3","author":"August DA","year":"1984","journal-title":"Clinical perspectives of human colorectal cancer metastasis. Cancer Metastasis Rev"},{"key":"CIT0035","first-page":"137","volume":"69","author":"Pollack VA","year":"1982","journal-title":"J Natl Cancer Inst"},{"key":"CIT0036","first-page":"1928","volume":"46","author":"Giavazzi R","year":"1986","journal-title":"Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into differ-ent sites of nude mice. Cancer Res"},{"key":"CIT0037","first-page":"1303","volume":"77","author":"Giavazzi R","year":"1986","journal-title":"Experimental nude mouse model of human colorectal cancer liver metastasis. J Nail Cancer Inst"},{"key":"CIT0038","first-page":"1943","volume":"48","author":"Morikawa K","year":"1988","journal-title":"Cancer Res"},{"key":"CIT0039","first-page":"6863","volume":"48","author":"Morikawa K","year":"1988","journal-title":"Cancer Res"},{"key":"CIT0040","first-page":"6906","volume":"49","author":"Jessup JM","year":"1989","journal-title":"Cancer Res"},{"key":"CIT0041","first-page":"1689","volume":"48","author":"Jessup JM","year":"1988","journal-title":"Cancer Res"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/ijc.2910390514","volume":"39","author":"Bresalier RS","year":"1987","journal-title":"Int J Cancer"},{"key":"CIT0043","first-page":"291","volume":"74","author":"Sordat B","year":"1984","journal-title":"Behring Inst Mitt"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/ijc.2910440131","volume":"44","author":"Schackert H","year":"1989","journal-title":"Int J Cancer"},{"key":"CIT0045","first-page":"2650","volume":"45","author":"dayman RV, Figenshau RS,","year":"1985","journal-title":"Transplantation of human renal carcinomas into athymic mice. Cancer Res"},{"key":"CIT0046","first-page":"4109","volume":"46","author":"Naito S","year":"1986","journal-title":"Cancer Res"},{"key":"CIT0047","first-page":"377","volume":"78","author":"Naito S","year":"1987","journal-title":"J Natl Cancer Inst"},{"key":"CIT0048","first-page":"149","volume":"9","author":"Fidler U","year":"1990","journal-title":"Orthotopic implantation is essential for the selection, growth and metastasis of human renal cell cancer in nude mice. Cancer Metastasis Rev"},{"key":"CIT0049","first-page":"913","volume":"72","author":"Kozlowski JM","year":"1984","journal-title":"J Natl Cancer Inst"},{"key":"CIT0050","first-page":"93","volume":"72","author":"Kerbel RS","year":"1984","journal-title":"Dexter D. A model of human cancer metastasis: extensive spontaneous and artificial metastasis of a human pigmented melanoma and derived variant sublines in nude mice. J Natl Cancer Inst"},{"issue":"3","key":"CIT0051","first-page":"1","volume":"4","author":"Kerbel RS","year":"1984","journal-title":"Invasion Metastasis"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1093\/jnci\/81.12.938","volume":"81","author":"Corail T","year":"1989","journal-title":"J Natl Cancer Inst"},{"key":"CIT0053","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0304-3835(80)90097-X","volume":"11","author":"Shafie SM","year":"1980","journal-title":"Cancer Lett"},{"key":"CIT0054","first-page":"717","volume":"50","author":"Price JE","year":"1990","journal-title":"Cancer Res"},{"key":"CIT0055","first-page":"375","volume":"45","author":"Levy JA","year":"1982","journal-title":"Growth and histology of a human mammary-carcinoma cell line at different sites in the athymic mouse. Br J Cancer"},{"key":"CIT0056","first-page":"617","volume":"43","author":"Ibrahiem EHI","year":"1983","journal-title":"Orthotopic implantation of primary (N44-(5-ni-tro-2-fury1)-2-thiazoly11) formamide-induced bladder cancer in bladder submucosa: an animal model for bladder cancer study. Cancer Res"},{"key":"CIT0057","first-page":"6660","volume":"47","author":"Ahlering TE","year":"1987","journal-title":"A new in vivo model to study invasion and metastasis of human bladder carcinoma. Cancer Res"},{"key":"CIT0058","first-page":"3522","volume":"44","author":"Kozlowski JM","year":"1984","journal-title":"Cancer Res"},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1038\/bjc.1982.310","volume":"46","author":"Kajiji SM","year":"1982","journal-title":"Br J Cancer"},{"key":"CIT0060","first-page":"53","volume":"26","author":"Vezeridis MP","year":"1985","journal-title":"Metastasis of human pancreatic cancer (HPC) to liver in nude mice. Proc Am Assn Cancer Res"},{"key":"CIT0061","first-page":"89","volume":"6","author":"Tan MU","year":"1985","journal-title":"Tumour Biol"},{"key":"CIT0062","first-page":"520","volume":"47","author":"Marineepla FM","year":"1989","journal-title":"The nude mouse as a model for the study of human pancreatic cancer. J Surg Res"},{"key":"CIT0063","first-page":"261","volume":"40","author":"Vezeridis MP","year":"1989","journal-title":"Invasion and metastasis following orthotopic transplantation of human pancreatic cancer in the nude mouse. J Surg Oncol"},{"key":"CIT0064","first-page":"5132","volume":"47","author":"McLemore TL","year":"1987","journal-title":"Cancer Res"},{"key":"CIT0065","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/BF00048482","volume":"2","author":"Meyvisch C","year":"1983","journal-title":"Cancer Metastasis Rev"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/BF00048224","volume":"1","author":"Poste G","year":"1982","journal-title":"Cancer Metastasis Rev"},{"key":"CIT0067","first-page":"220","volume":"1","author":"Miller FR","year":"1981","journal-title":"Invasion Metastasis"},{"key":"CIT0068","first-page":"83","volume":"62","author":"Malave I","year":"1979","journal-title":"Influence of inoculation site on development of the Lewis lung carcinoma and suppressor cell activity in syngeneic mice. J Nail Cancer Inst"},{"key":"CIT0069","first-page":"129","volume":"10","author":"Li L","year":"1990","journal-title":"Intrabronchial implantation of the Lewis lung tumor cell does not favor tumorigenicity and metastasis. Invasion Metastasis"}],"container-title":["Acta Oncologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.3109\/02841869109092438","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:37:28Z","timestamp":1791365848000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicaljournalssweden.se\/actaoncologica\/article\/view\/32480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,1]]},"references-count":66,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2013,7,5]]},"published-print":{"date-parts":[[1991,1]]}},"alternative-id":["10.3109\/02841869109092438"],"URL":"https:\/\/doi.org\/10.3109\/02841869109092438","relation":{},"ISSN":["0284-186X","1651-226X"],"issn-type":[{"value":"0284-186X","type":"print"},{"value":"1651-226X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,1]]}}}