{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:13:18Z","timestamp":1794323598908,"version":"4.9.0"},"reference-count":67,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Economics"],"published-print":{"date-parts":[[2016,3,3]]},"DOI":"10.3111\/13696998.2015.1116990","type":"journal-article","created":{"date-parts":[[2015,11,4]],"date-time":"2015-11-04T17:22:01Z","timestamp":1446657721000},"page":"265-276","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":5,"title":["Febuxostat in the management of gout: a cost-effectiveness analysis"],"prefix":"10.3111","volume":"19","author":[{"given":"Lee J.","family":"Smolen","sequence":"first","affiliation":[{"name":"aMedical Decision Modeling Inc., Indianapolis, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Gahn","sequence":"additional","affiliation":[{"name":"aMedical Decision Modeling Inc., Indianapolis, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghaith","family":"Mitri","sequence":"additional","affiliation":[{"name":"bnaviHealth, Inc. Brentwood, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki","family":"Shiozawa","sequence":"additional","affiliation":[{"name":"cTakeda Pharmaceuticals International, Inc., Deerfield, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2015,11,23]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204463"},{"issue":"2","key":"CIT0002","first-page":"ii2","volume":"48","author":"Doherty M","year":"2009","journal-title":"Rheumatology (Oxford)"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1002\/art.30520"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/j.curtheres.2013.04.003"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.75.Suppl_5.S13"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-143-7-200510040-00009"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21772"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0b013e328330d9d0"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-15-122"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-014-1302-4"},{"key":"CIT0011","doi-asserted-by":"crossref","unstructured":"Goicoechea M, Garcia de Vinuesa S, Verdalles U, et al. Allopurinol and progression of ckd and cardiovascular events: long-term follow-up of a randomized clinical trial. Am J Kidney Dis 2015;65:543-9","DOI":"10.1053\/j.ajkd.2014.11.016"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e3282f54d03"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-64-2-229"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2011.05.010"},{"key":"CIT0015","unstructured":"Joseph-Ridge N. A phase 3, randomized, multicenter, allopurinol and placebo-controlled study assessing the safety and efficacy of oral febuxostat in subjects with gout (APEX) data on file. Deerfield, IL: TAP Pharmaceutical Products Inc\/Takeda Pharmaceutical Company Limited, 2004"},{"key":"CIT0016","unstructured":"Joseph-Ridge N. A phase 3, randomized, multicenter study comparing the safety and efficacy of oral febuxostat versus allopurinol in subjects with gout (FACT) data on file. Deerfield, IL: TAP Pharmaceutical Products Inc\/Takeda Pharmaceutical Company Limited, 2004"},{"key":"CIT0017","unstructured":"Lademacher C. A Phase 3, randomized, multicenter, double-blind, allopurinol-controlled study assessing the efficacy and safety of oral febuxostat in subjects with gout (CONFIRMS) data on file. Deerfield, IL: TAP Pharmaceutical Products Inc\/Takeda Pharmaceutical Company Limited, 2008"},{"key":"CIT0018","unstructured":"Watson Laboratories Inc. Allopurinol [Package Insert] [Internet]. Corona, CA: Watson Laboratories Inc., 2006. http:\/\/pi.watson.com\/data_stream.asp?product_group=1197&p=pi&language=E. Accessed March 31, 2014"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.4065\/81.7.925"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050373"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1186\/ar2978"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1002\/art.24209"},{"key":"CIT0023","unstructured":"U.S. Census Bureau. 2010 census data [Internet]. Washington, DC: U.S. Census Bureau, 2011. http:\/\/census.gov\/2010census\/data\/. Accessed March 31, 2014"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.024091"},{"key":"CIT0025","unstructured":"Xiangyang. The evaluation of clinical outcomes associated with the use of febuxostat and allopurinol in the treatment of gout: reanalysis using the GE EMR database version 2.0 data on file. Deerfield, IL: Takeda Pharmaceutical Company Limited, 2012"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken457"},{"key":"CIT0027","unstructured":"Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey 20072008 [Internet]. Hyattsville, MD: National Center for Health Statistics, 2009. http:\/\/www.cdc.gov\/nchs\/nhanes\/search\/nhanes07_08.aspx. Accessed March 31, 2014"},{"key":"CIT0028","unstructured":"Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey 20092010 [Internet]. Hyattsville, MD: National Center for Health Statistics, 2011. http:\/\/www.cdc.gov\/nchs\/nhanes\/search\/nhanes09_10.aspx. Accessed March 31, 2014"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2007.00270.x"},{"key":"CIT0030","volume-title":"Uloric (febuxostat) [Package Insert]","author":"Takeda Pharmaceuticals America, Inc","year":"2009"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90743-5"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-014-0617-1"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4733.1998.120131.x"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.080487"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.3109\/03009742.2010.507218"},{"key":"CIT0036","unstructured":"Centers for Disease Control and Prevention. Incidence of diagnosed diabetes per 1,000 population aged 1879 years, 19802011 [Internet]. Atlanta, GA: Diabetes Public Health Resource, 2012. http:\/\/www.cdc.gov\/diabetes\/statistics\/incidence\/fig3.htm. Accessed March 31, 2014"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.121061"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-0288"},{"key":"CIT0039","first-page":"1","volume":"62","author":"Arias E","year":"2014","journal-title":"National Vital Statistics Report"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21773"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1080\/15257770802136032"},{"key":"CIT0042","first-page":"S672","volume":"58","author":"Khanna D","year":"2008","journal-title":"Arthritis Rheum"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1016\/S1098-3015(10)70824-X"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1002\/art.30655"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-9-400"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041031"},{"key":"CIT0047","unstructured":"Schulman K. Clinical & economic outcomes in patients with a history of chronic kidney disease & gout initiating therapy with allopurinol or febuxostat. Data on file. Deerfield, IL: TAP Pharmaceutical Products Inc\/Takeda Pharmaceutical Company Limited, 2014"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2011.563284"},{"key":"CIT0049","unstructured":"American Medical Association. AMA CodeManager: CPT Code\/Relative Value Search [Internet].Chicago, IL: American Medical Association, 2013. https:\/\/ocm.ama-assn.org\/OCM\/CPTRelativeValue Search.do. Accessed March 31, 2014"},{"key":"CIT0050","unstructured":"Avalere Health LLC. Trendwatch 2013 chartbook: trends affecting hospitals and health systems [Internet]. Chicago, IL: American Hospital Association, 2013. http:\/\/www.aha.org\/research\/reports\/index.shtml. Accessed March 31, 2014"},{"key":"CIT0051","unstructured":"Walk-In Lab. Uric acid serum test [Internet]. Kidney Tests. Mandeville, LA: Walk In Lab, LLC, 2014. http:\/\/www.walkinlab.com\/kidney-tests\/uricacidserumtest.html. Accessed March 31, 2014"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0b013e3181945d2c"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.11.017"},{"key":"CIT0054","volume-title":"USRDS 2011 annual data report: atlas of chronic kidney disease and end-stage renal disease in the United States. Chapter 11 [Internet]","author":"U.S. Renal Data System","year":"2011"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1002\/art.33369"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2015.21.2.165"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1136\/ebmed-2011-100065"},{"key":"CIT0058","unstructured":"Bureau of Labor Statistics. Consumer price index - all urban consumers. Medical Care [Internet]. Washington, DC: Bureau of Labor Statistics, 2014. http:\/\/data.bls.gov\/cgi-bin\/surveymost?cu. Accessed March 31, 2014"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.2165\/11535770-000000000-00000"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.7326\/M14-0227"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2011.09.033"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01580210"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2013.01.2626"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-201676"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1002\/art.30119"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.091462"},{"key":"CIT0067","unstructured":"Truven Health Analytics. RED BOOK Online [Internet]. Ann Arbor, MI: Truven Health Analytics, 2014. http:\/\/www.micromedexsolutions.com. Accessed March 31, 2014"}],"container-title":["Journal of Medical Economics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3111\/13696998.2015.1116990","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,6]],"date-time":"2020-09-06T09:07:05Z","timestamp":1599383225000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3111\/13696998.2015.1116990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,23]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3,3]]}},"alternative-id":["10.3111\/13696998.2015.1116990"],"URL":"https:\/\/doi.org\/10.3111\/13696998.2015.1116990","relation":{},"ISSN":["1369-6998","1941-837X"],"issn-type":[{"value":"1369-6998","type":"print"},{"value":"1941-837X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,23]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ijme20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ijme20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2015-11-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-11-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}