{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:00:29Z","timestamp":1791255629593,"version":"4.1.0"},"reference-count":55,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foot Ankle Int."],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p> Background: Chronic Achilles tendinosis is a relatively common but difficult orthopedic condition to treat. In this study, autologous platelet rich plasma (PRP), a concentrated bioactive blood component rich in cytokines and growth factors, was evaluated to determine its potential long-term efficacy in treating chronic cases of Achilles tendinosis resistant to traditional nonoperative management. Methods: Thirty patients with chronic Achilles tendinosis who did not respond to a minimum of 6 months of traditional nonoperative treatment modalities were treated with a single ultrasound guided injection of PRP. AOFAS scoring was completed for all patients pretreatment and at 0, 1, 2, 3, 6, 12, and 24 months post-treatment. MRI and\/or ultrasound studies were completed for all patients pre-treatment and at 6 months post-treatment. Prior to the PRP treatment all of the patients in this study were considering surgical Achilles repair for their severe symptoms. Results: The average AOFAS score increased from 34 (range, 20 to 60) to 92 (range, 87 to 100) by 3 months after PRP treatment and remained elevated at 88 (range, 76 to 100) at 24 months post-treatment. Pretreatment imaging abnormalities present in the Achilles tendon on MRI and ultrasound studies resolved in 27 of 29 patients at 6 months post-treatment. Clinical success was achieved in 28 of 30 patients. Conclusion: Platelet-rich plasma was used effectively to treat chronic recalcitrant cases of Achilles tendinosis. <\/jats:p><jats:p> Level of Evidence: IV, Case Series <\/jats:p>","DOI":"10.3113\/fai.2012.0379","type":"journal-article","created":{"date-parts":[[2012,7,26]],"date-time":"2012-07-26T16:58:33Z","timestamp":1343321913000},"page":"379-385","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":106,"title":["Platelet Rich Plasma Treatment for Chronic Achilles Tendinosis"],"prefix":"10.1177","volume":"33","author":[{"given":"Raymond Rocco","family":"Monto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,5,1]]},"reference":[{"key":"bibr1-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2007.035543"},{"key":"bibr2-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.22274"},{"key":"bibr3-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1016\/j.orthres.2004.08.015"},{"key":"bibr4-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000255543.43695.1d"},{"key":"bibr5-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1080\/00016470410001708190"},{"key":"bibr6-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199507000-00021"},{"key":"bibr7-FAI.2012.0379","first-page":"37","volume":"17","author":"Barrett S","year":"2004","journal-title":"Podiatry Today."},{"key":"bibr8-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1177\/036354658401200301"},{"key":"bibr9-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2007.040071"},{"key":"bibr10-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1177\/107110070302400306"},{"key":"bibr11-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2010.081554.40"},{"key":"bibr12-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508314430"},{"key":"bibr13-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1986"},{"key":"bibr14-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2010.079822"},{"key":"bibr15-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000138251.07040.51"},{"key":"bibr16-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1159\/000110862"},{"key":"bibr17-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.I.01158"},{"key":"bibr18-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1097\/01.bto.0000261868.03232.dd"},{"key":"bibr19-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2008.06.025"},{"key":"bibr20-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200910000-00002"},{"key":"bibr21-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508330974"},{"key":"bibr22-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21368"},{"key":"bibr23-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.37.2.149"},{"key":"bibr24-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2008.11.026"},{"key":"bibr25-FAI.2012.0379","doi-asserted-by":"publisher","DOI":"10.3113\/FAI.2009.1101"},{"key":"bibr26-FAI.2012.0379","first-page":"2604","volume":"92","author":"Maffulli N","year":"2010","journal-title":"J. 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