{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T08:26:15Z","timestamp":1793607975966,"version":"4.5.0"},"reference-count":0,"publisher":"Nepal Journals Online (JOL)","issue":"35","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nep J Oph"],"abstract":"<jats:p>Introduction: Adult-onset xanthogranuloma (AOX) is a rare, benign inflammatory disorder within the spectrum of non-Langerhans cell histiocytosis, often manifesting as localised skin lesions in middle-aged adults and frequently misdiagnosed due to its nonspecific presentation.\nCase: A 43-year-old woman developed a painless, progressively enlarging mass on her right upper eyelid over four months, with histopathology confirming AOX.\nObservation: Following surgical debulking and adjunctive intralesional corticosteroid (triamcinolone acetonide) injection, the patient exhibited significant clinical improvement and no recurrence at three months. This outcome supports emerging evidence that a combination of surgery and corticosteroid therapy effectively reduces lesion size and recurrence rates in localised AOX.\nConclusion: The multimodal approach combining surgical excision and intralesional corticosteroid injections provides a conservative and effective management strategy for AOX, with favourable outcomes and minimal complications. Further research is warranted to standardise treatment protocols for this rare orbital disease.<\/jats:p>","DOI":"10.3126\/nepjoph.v18i35.85672","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:43:48Z","timestamp":1790603028000},"page":"105-12","source":"Crossref","is-referenced-by-count":0,"title":["Management of Adult-onset Eyelid Xanthogranuloma: Debulking Surgery Coupled with Intralesional Corticosteroids"],"prefix":"10.3126","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4090-4871","authenticated-orcid":false,"given":"Najmatuzzahra","family":"Kamaluddin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0604-1500","authenticated-orcid":false,"given":"Andi","family":"Pratiwi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1670","published-online":{"date-parts":[[2026,4,3]]},"container-title":["Nepalese Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/85672\/74777","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/85672\/74777","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T07:27:53Z","timestamp":1793604473000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/view\/85672"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,3]]},"references-count":0,"journal-issue":{"issue":"35","published-online":{"date-parts":[[2026,8,17]]}},"URL":"https:\/\/doi.org\/10.3126\/nepjoph.v18i35.85672","relation":{},"ISSN":["2091-0320","2072-6805"],"issn-type":[{"value":"2091-0320","type":"electronic"},{"value":"2072-6805","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4,3]]}}}