{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T08:29:34Z","timestamp":1649060974232},"reference-count":0,"publisher":"Nepal Journals Online (JOL)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nep J Oph"],"abstract":"<jats:p>Background: Ocular complications of leprosy can lead to blindness. Objective: To report the pattern and determinants of ocular complications in patients with leprosy from eastern Nepal. Methods: A cross-sectional study was carried out analyzing one hundred and eighty six patients of leprosy presenting between Jan 2002-Nov 2004. All the patients were categorized using WHO and Ridley and Jopling classification. After determining bacillary indices in all of them, a detailed ocular examination was carried out. Independent risk factors were determined for ocular involvement. Results: Ocular complications were found in 30.65 % of the leprosy patients; lagophthalmos (17.74%) was the most frequent followed by uveitis (8.60%). Most of the patients having visual loss had it due to corneal complications and none of the patients with uveitis had vision &lt;6\/18. The patients released from treatment (83.33%) and those currently on treatment (31.63%) had higher occurrence of complications. Risk factors for ocular involvement were higher bacillary index, longer disease duration (p=0.031, RR=1.109, 95% CI=1.009-01.218) and decreased corneal sensation (p=0.001, RR=3.564; 95% CI =2.014-6.306). Higher Schirmer values (p=0.012, RR=0.935, 95% CI=0.888-0.985) were found to be protective for ocular complications. Statistics: SPSS ver 10.0 was used for data analysis. The P value of &lt;0.05 was considered as significant. Conclusions: The prevalence of complications is high in patients released from treatment for leprosy. Cornea-related complications are the most important cause of visual disability and blindness. Risk factors for ocular complications are higher bacillary index, longer disease duration and decreased corneal sensation. Key words: leprosy; Nepal; ocular complications; risk factors DOI: 10.3126\/nepjoph.v1i1.3666 Nep J Oph 2009;1(1):2-8<\/jats:p>","DOI":"10.3126\/nepjoph.v1i1.3666","type":"journal-article","created":{"date-parts":[[2010,9,17]],"date-time":"2010-09-17T13:35:19Z","timestamp":1284730519000},"page":"2-8","source":"Crossref","is-referenced-by-count":0,"title":["Pattern and determinants of ocular complications in leprosy patients in eastern Nepal"],"prefix":"10.3126","volume":"1","author":[{"given":"S","family":"Javvadhi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Das","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Agrawal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1670","published-online":{"date-parts":[[1970,1,1]]},"container-title":["Nepalese Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/3666\/3145","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/3666\/3145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T17:02:02Z","timestamp":1546016522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/view\/3666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,9,16]]}},"URL":"https:\/\/doi.org\/10.3126\/nepjoph.v1i1.3666","relation":{},"ISSN":["2091-0320","2072-6805"],"issn-type":[{"value":"2091-0320","type":"electronic"},{"value":"2072-6805","type":"print"}],"subject":[],"published":{"date-parts":[[1970,1,1]]}}}