{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T06:26:25Z","timestamp":1793600785859,"version":"4.5.0"},"reference-count":0,"publisher":"Nepal Journals Online (JOL)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nep J Oph"],"abstract":"<jats:p>Background: Kissing nevus is a congenital nevus in adjacent parts of the eyelids. Malignant transformation of kissing or divided nevi of the eyelids is rarely described. Objective: To report a very rare case of malignant transformation of kissing nevus with ocular and extraocular spread. Case: A 57- year- old man with 6\/6 visual acuity in both eyes presented with a kissing nevus present since birth in right upper and lower eyelids which had a slow growth phase. The upper lid in the area of the nevus was thickened with a 20x12x15 mm black pigmented crusted hemorrhagic nodular lesions. The lower lid had a 6 mm black pigmented ulcerated lesion over the pre-existing nevus in the lateral third of the lid with full thickness infiltration. Another 5x4 mm pigmented lesion over the lower medial lid margin with a thickness of about 3 mm extended to the conjunctival side of the lower lid. Right sided pre-auricular and submaxillary nodes were palpable. A biopsy of tissue samples from the eyelid and pre-auricular nodes were consistent with malignant melanoma.Conclusion: Malignant transformation of kissing nevus is rare. It can spread to the conjunctiva, pre-auricular and sub-mandibular lymphnodes.DOI:\u00a0http:\/\/dx.doi.org\/10.3126\/nepjoph.v4i2.6555 Nepal J Ophthalmol 2012; 4 (2): 329-332 \u00a0<\/jats:p>","DOI":"10.3126\/nepjoph.v4i2.6555","type":"journal-article","created":{"date-parts":[[2012,7,30]],"date-time":"2012-07-30T05:34:44Z","timestamp":1343626484000},"page":"329-332","source":"Crossref","is-referenced-by-count":9,"title":["Malignant transformation of kissing nevus- a rare entity"],"prefix":"10.3126","volume":"4","author":[{"given":"R Sitaula","family":"Kharel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Bhatta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G B","family":"Shrestha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J K","family":"Shrestha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1670","published-online":{"date-parts":[[2012,7,26]]},"container-title":["Nepalese Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/6555\/5344","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/6555\/5344","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T05:30:51Z","timestamp":1793597451000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/view\/6555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,26]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2012,7,30]]}},"URL":"https:\/\/doi.org\/10.3126\/nepjoph.v4i2.6555","relation":{},"ISSN":["2091-0320","2072-6805"],"issn-type":[{"value":"2091-0320","type":"electronic"},{"value":"2072-6805","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7,26]]}}}