{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T06:29:08Z","timestamp":1793600948632,"version":"4.5.0"},"reference-count":0,"publisher":"Nepal Journals Online (JOL)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nep J Oph"],"abstract":"<jats:p>Background: Orbital involvement in Wegener\u2019s Granulomatosis (WG) is rare and has an overall good prognosis. Case: A 60-year-old hypertensive Indian female presented with vision loss and painful proptosis of left eye. Orbital incisional biopsy suggested necrotising small vessel inflammation. The saddle nose deformity and pedal nodulo- ulcerative lesions further consolidated the diagnosis of Wegener\u2019s granulomatosis. Systemic immunosuppressant provided remission and the only relapse was managed successfully with intravenous Rituximab. Conclusion: Wegener\u2019s granulomatosis should be kept in the differential diagnosis of painful proptosis with a diffuse orbital mass in an elderly patient presenting with profound vision loss. Newer immune modulating agents are useful adjuncts in preventing relapses of this fatal disease.<\/jats:p>","DOI":"10.3126\/nepjoph.v7i1.13173","type":"journal-article","created":{"date-parts":[[2015,9,17]],"date-time":"2015-09-17T22:20:34Z","timestamp":1442528434000},"page":"65-68","source":"Crossref","is-referenced-by-count":4,"title":["Orbital presentation of systemic vasculitis: a diagnostic and management challenge"],"prefix":"10.3126","volume":"7","author":[{"given":"M","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z","family":"Zadeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1670","published-online":{"date-parts":[[2015,9,17]]},"container-title":["Nepalese Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/13173\/10598","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/13173\/10598","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T06:02:18Z","timestamp":1793599338000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/view\/13173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,17]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,9,17]]}},"URL":"https:\/\/doi.org\/10.3126\/nepjoph.v7i1.13173","relation":{},"ISSN":["2091-0320","2072-6805"],"issn-type":[{"value":"2091-0320","type":"electronic"},{"value":"2072-6805","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9,17]]}}}