{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T15:23:53Z","timestamp":1648913033965},"reference-count":0,"publisher":"Nepal Journals Online (JOL)","issue":"2","license":[{"start":{"date-parts":[[2017,3,22]],"date-time":"2017-03-22T00:00:00Z","timestamp":1490140800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nep J Oph"],"abstract":"<jats:p>Background: Keratoconus is a corneal dystrophy characterized by progressive thinning, conical shape of the cornea and irregular astigmatism. It is particularly insidious when it occurs in very young patients. Case: We report the case of a 10-year-old child with an aggressive stage III keratoconus, who was suggested to undergo a Penetrating Keratoplasty. We performed Corneal Collagen Cross-linking with epithelium removal instead, which was successful in arresting the rapid progression of keratoconus. Observations: Eighteen months later, Kmax had decreased by 1.3 D, astigmatism by 0.8 D, thinnest pachimetry had improved by 69 \u03bcm and CDVA was 20\/32. Conclusion: This case confirms that Corneal Collagen Cross-linking is a safe and effective procedure for the treatment of keratoconus even in its aggressive forms. We encourage ophthalmic surgeons to favor conservative treatments when dealing with very young patients.\u00a0<\/jats:p>","DOI":"10.3126\/nepjoph.v8i2.17015","type":"journal-article","created":{"date-parts":[[2017,3,22]],"date-time":"2017-03-22T10:03:44Z","timestamp":1490177024000},"page":"174-177","source":"Crossref","is-referenced-by-count":0,"title":["Corneal cross-linking in a 10-year-old child with stage III keratoconus"],"prefix":"10.3126","volume":"8","author":[{"given":"Marco","family":"Abbondanza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina De","family":"Felice","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Abbondanza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1670","published-online":{"date-parts":[[2017,3,22]]},"container-title":["Nepalese Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/17015\/13823","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/download\/17015\/13823","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T17:00:23Z","timestamp":1546016423000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nepjol.info\/index.php\/NEPJOPH\/article\/view\/17015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,22]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,3,22]]}},"URL":"https:\/\/doi.org\/10.3126\/nepjoph.v8i2.17015","relation":{},"ISSN":["2091-0320","2072-6805"],"issn-type":[{"value":"2091-0320","type":"electronic"},{"value":"2072-6805","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3,22]]}}}