{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T06:28:59Z","timestamp":1762928939347,"version":"3.40.5"},"reference-count":0,"publisher":"Nepal Journals Online (JOL)","issue":"4","license":[{"start":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T00:00:00Z","timestamp":1640908800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nepal J Epidemiology"],"abstract":"<jats:p>Background:\u00a0 The novel coronavirus disease 2019 (COVID-19) outbreak, caused by the pathogenic severe acute respiratory syndrome-2 (SARS-CoV-2) virus, is exponentially spreading across the globe.\nMethods: The current systematic review was performed utilizing electronic databases i.e. PubMed, MEDLINE and EMBASE. We searched for the keywords \"COVID-19 AND \"pregnancy\" between January 1st, 2020 until December 31, 2020.\nResults: Out of 4005 records which were identified, 36 original studies were included in this systematic review. Pooled prevalence of vertical transmission was 10%, 95% CI: 4-17%. Pooled prevalence of neonatal mortality was 7%, 95% CI: 0-21%.\nConclusion: The contemporary evidence suggests that the incubation period of COVID-19 is 2-14 days, and this infection could be transmitted even from the infected asymptomatic individuals. It is found that the clinical presentation of pregnant women with COVID-19 infection is comparable with the infected non-pregnant females, and the frequent symptoms were fever, cough, myalgia, sore throat and malaise. There are some cases with severe maternal morbidity and perinatal deaths secondary to COVID-19 infection. Under these circumstances, the pregnant women should focus on maintaining personal hygiene, proper nutrition and extreme social distancing to reduce the risk of COVID-19. Therefore, a systematic data reporting for evidence base clinical assessment, management and pregnancy outcomes is essential for prevention of COVID-19 infection among pregnant women.<\/jats:p>","DOI":"10.3126\/nje.v11i4.41911","type":"journal-article","created":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T16:49:41Z","timestamp":1640969381000},"page":"1103-1125","source":"Crossref","is-referenced-by-count":6,"title":["Epidemiologic characteristics, clinical management and Public Health Implications of Coronavirus Disease 2019 (COVID-19) in Pregnancy: A Systematic Review and meta-analysis"],"prefix":"10.3126","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0851-4762","authenticated-orcid":false,"given":"Brijesh","family":"Sathian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2880-4695","authenticated-orcid":false,"given":"Indrajit","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8431-8937","authenticated-orcid":false,"given":"Ahammed A","family":"Mekkodathil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5523-8583","authenticated-orcid":false,"given":"Edwin","family":"Van Teijlingen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4089-454X","authenticated-orcid":false,"given":"Ana Beatriz","family":"Pizarro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9947-8730","authenticated-orcid":false,"given":"Mohammad","family":"Asim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1269-2238","authenticated-orcid":false,"given":"Maraeh Angela","family":"Mancha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9257-2775","authenticated-orcid":false,"given":"Russell","family":"Kabir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5706-6479","authenticated-orcid":false,"given":"Padam","family":"Simkhada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5240-0493","authenticated-orcid":false,"given":"Israel J\u00fanior Borges do","family":"Nascimento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanadi","family":"Al Hamad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1670","published-online":{"date-parts":[[2021,12,31]]},"container-title":["Nepal Journal of Epidemiology"],"original-title":[],"link":[{"URL":"https:\/\/www.nepjol.info\/index.php\/NJE\/article\/download\/41911\/31950","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nepjol.info\/index.php\/NJE\/article\/download\/41911\/31950","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T12:33:59Z","timestamp":1641299639000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nepjol.info\/index.php\/NJE\/article\/view\/41911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,31]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,12,31]]}},"URL":"https:\/\/doi.org\/10.3126\/nje.v11i4.41911","relation":{},"ISSN":["2091-0800"],"issn-type":[{"type":"electronic","value":"2091-0800"}],"subject":[],"published":{"date-parts":[[2021,12,31]]}}}