{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T10:49:19Z","timestamp":1791888559248,"version":"4.3.4"},"reference-count":0,"publisher":"Czech Society of Ophthalmology of the CzMA","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Purpose: To compare safety and efficacy of ophthalmic viscosurgical devices (OVDs) \u2013 OphteisBio 3.0 (Rayner) and Healon Endocoat (J&amp;J Vision) in phacoemulsification cataract removal surgery.\n\nMaterials and Methods: In this prospective subject\/evaluator-masked post-market randomized study patients undergoing phacoemulsification were assigned to receive one of two hyaluronate-based OVDs \u2013 OphteisBio 3.0 and Healon Endocoat. The outcomes were the rate of intraocular pressure (IOP) spikes \u2265 30 mmHg at the 7-day postoperative visit, endothelial cell density changes, the surgeon acceptance rate, IOP change from baseline, rates of inflammation and rates of serious and\/or device-related adverse events.\n\nResults: The study included 293 eyes \u2013 146 in the Ophteis group and 147 in the Healon group. No IOP spikes were noted at the 7-day postoperative visit with mean IOP of 14.5 mmHg for Ophteis group and 14.3 mmHg for the Healon group. The mean endothelial cell density loss after the surgery was 9.8% in the Ophteis group and 10.2% in the Healon group with no statistically significant difference between the two OVD groups (p = 0.6292). At the 7-day visit, anterior chamber flare was absent in 98% and 99% of eyes in the Ophteis and Healon group, respectively. 82% of eyes had no anterior chamber cells at 7-day visit in both groups. No adverse events were recorded during surgery and at 7-day follow up. No clinically relevant differences were found between the two OVDs.\n\nConclusion: Ophteis 3.0 and Healon Endocoat have comparable results following phacoemulsification surgery.<\/jats:p>","DOI":"10.31348\/2026\/29","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T10:15:22Z","timestamp":1791886522000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Safety and Efficacy of Two Dispersive Hyaluronate OVDs Used in Cataract Surgery"],"prefix":"10.31348","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3213-640X","authenticated-orcid":false,"given":"Pavel","family":"Stod\u016flka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Jir\u00e1tkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate\u0159ina","family":"Klime\u0161ov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuzana","family":"Pracha\u0159ov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Tihelkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Uhl\u00e1\u0159ov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2166-4401","authenticated-orcid":false,"given":"Martin","family":"Slov\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Rand\u00e1rov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16213","published-online":{"date-parts":[[2026,8,3]]},"container-title":["Czech and Slovak Ophthalmology"],"original-title":[],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T10:15:22Z","timestamp":1791886522000},"score":1,"resource":{"primary":{"URL":"https:\/\/cs-ophthalmology.cz\/en\/journal\/articles\/571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,3]]},"references-count":0,"URL":"https:\/\/doi.org\/10.31348\/2026\/29","relation":{},"ISSN":["1211-9059","1805-4447"],"issn-type":[{"value":"1211-9059","type":"print"},{"value":"1805-4447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,3]]}}}