{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T23:02:34Z","timestamp":1775775754273,"version":"3.50.1"},"reference-count":36,"publisher":"University of Toronto Press Inc. (UTPress)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical and Investigative Medicine"],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:sec><jats:title>Purpose:<\/jats:title><jats:p> This study aimed to establish a CT imaging grading system and explore its value in evaluating upper urinary tract calculi associated with kidney infections. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> CT images of 126 patients with kidney infections caused by upper urinary tract calculi were retrospectively analyzed. The CT grading system was developed based on CT images. CT images were classified into 4 grades. General information, symptoms, and clinical findings of patients in different CT grades were analyzed. With the occurrence of systemic inflammatory response syndrome (SIRS) as the endpoint, univariate and multivariate analysis was conducted to analyze the risk factors of SIRS. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Patients with fever or diabetes had higher CT grades, and the following examination data revealed significant differences across the various CT grades ( P &lt; 0.05): the white blood cell count, urine leucocytes count, CT1, CT2, maximum body temperature, duration of disease, the proportion of blood neutrophils, the size of stones, and levels of the C-reactive protein and procalcitonin. Only CT grading was statistically significant after multivariate analysis. According to the values of the partial regression coefficient (B), the higher the CT grade, the greater the risk of SIRS. The risk of SIRS was 4.472 times higher with each increment of the CT grade. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> The CT grade is directly associated with clinical symptoms and the risk of SIRS. <\/jats:p><\/jats:sec>","DOI":"10.3138\/cim-2024-0107","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T16:15:10Z","timestamp":1727367310000},"page":"7-17","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Application of CT Imaging Grading System in Upper Urinary Tract Calculi with Kidney Infection"],"prefix":"10.3138","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6991-1404","authenticated-orcid":false,"given":"Jianping","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Urology, Affiliated Haixia Hospital of Huaqiao University (910th Hospital of PLA), Quanzhou, China"},{"name":"The Graduate School of Fujian Medical University, Fuzhou, China"},{"name":"*These 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