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Therefore, the present study aimed to create and evaluate 3D models representing benzodiazepine drugs and their binding sites. We hypothesized that 3D models of benzodiazepines (3D BZDs) could be used effectively as teaching tools, making it possible to learn about the mechanisms of action and their functions during the training of veterinary medicine students. In this study, 52 students from a veterinary medicine course participated and were divided equally into two groups: the 3D group (G3D) comprised students who used 3D BZDs, and the control group (CG) comprised students who used flat schemes for learning. A pre-test, post-test, and satisfaction questionnaire (each comprising 10 questions) were used to assess the student performance in both groups. Between the pre-tests and post-tests, the G3D group showed greater improvements in their scores than the CG group, suggesting that use of 3D BZDs was effective at promoting student learning. The satisfaction evaluation revealed good acceptance of the methodology employed. In conclusion, the use of 3D printed models can contribute to learning pharmacology and anesthesiology.<\/jats:p>","DOI":"10.3138\/jvme-2024-0158","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T16:10:52Z","timestamp":1783959052000},"source":"Crossref","is-referenced-by-count":0,"title":["Creation of Digital and 3D-Printed Models to Teach the Mechanisms of Action of Benzodiazepines (BZDs) to Veterinary Medicine Students"],"prefix":"10.3138","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3609-4710","authenticated-orcid":true,"given":"Alcides Loureiro","family":"Santos","sequence":"first","affiliation":[{"name":"Federal University of Acre, Center for Biological and Natural Sciences, BR-364, Km 04, Industrial District, Rio Branco, Acre, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8842-6684","authenticated-orcid":true,"given":"Regiane Guimar\u00e3es","family":"da Silva","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Center for Biological and Natural Sciences, BR-364, Km 04, Industrial District, Rio Branco, Acre, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5352-405X","authenticated-orcid":true,"given":"Yuri Karaccas","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine of the Federal Fluminense University (UFF) in Niter\u00f3i, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1696","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"issue":"1","key":"e_1_3_6_2_2","first-page":"33","article-title":"Simulation in teaching regional anesthesia: current perspectives","volume":"8","author":"Udani AD","year":"2015","unstructured":"Udani AD, Kim TE, Howard SK, Mariano ER. 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